Detection of 14-3-3 brain protein in the cerebrospinal fluid of patients with paraneoplastic neurological disorders

Annals of Neurology

Volumn 46, Issue 5, 1999, Pages 774-777

  Saiz, Albert ^a   Graus, Francesc ^a   Dalmau, Josep ^c   Pifarré, Alex ^a   Marín, Concepció ^a,b   Tolosa, Eduardo ^a,b  

^a HOSPITAL CLÍNIC   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN PROTEIN;

ADULT; AGED; ARTICLE; CEREBROSPINAL FLUID ANALYSIS; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; ENCEPHALITIS; FEMALE; HUMAN; IMMUNOBLOTTING; MAJOR CLINICAL STUDY; MALE; PARANEOPLASTIC SYNDROME; PRIORITY JOURNAL; PROTEIN DETERMINATION;

14-3-3 PROTEINS; AGED; BRAIN; CREUTZFELDT-JAKOB SYNDROME; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; IMMUNOBLOTTING; LIMBIC ENCEPHALITIS; MALE; MIDDLE AGED; PARANEOPLASTIC CEREBELLAR DEGENERATION; PARANEOPLASTIC SYNDROMES, NERVOUS SYSTEM; PREDICTIVE VALUE OF TESTS; PROTEINS; TYROSINE 3-MONOOXYGENASE;

EID: 0032703952     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(199911)46:5<774::AID-ANA14>3.0.CO;2-N     Document Type: Article

References (15)

1. Zerr I, Bodemer M, Gefeller O, et al. Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease. Ann Neurol 1998;43:32-40
2. Hsich G, Kenney K, Gibbs CJ, et al. The 14-3-3 brain protein in cerebrospinal fluid as marker for transmissible spongiform encephalopathies. N Engl J Med 1996;335:924-930
3. Dalmau J, Graus F. Paraneoplastic syndromes. In: Samuels MA, Feste S, eds. Office practice of neurology. New York: Churchill Livingstone, 1996:925-934
4. Stewart BJ, Lennon VA, Macauley RJB, Donat JR. Adenocarcinoma of the lung and ANNA-1 seropositivity presenting as rapidly progressive dementia and myoclonus. Neurology 1998; 50:A383 (Abstract)
5. Brown P, Carhala F, Castaigne P, Gajdusek DC, Creutzfeldt-Jakob disease: clinical analysis of a consecutive series of 230 neuropathologically verified cases. Ann Neurol 1986;20:597-602
6. Parchi P, Castellani R, Capellari S, et al. Molecular basis of phenorypic variability in sporadic Creutzfeldt-Jakob disease. Ann Neurol 1996;39:767-778
7. Report of a WHO consultation. Global surveillance, diagnosis and therapy of human transmissible spongiform encephalopathies. WHO/EMC/ZDI/98.9. World Health Organization: Geneva, 1998
8. Kreczschmar HA, Ironside J, DeArmond S, Tatcishi J. Diagnostic criteria for sporadic Creutzfeldt-Jakob disease. Arch Neurol 1996;35:385-395
9. Masters CL, Harris JO, Gajdusek DC, et al. Creutzfeldt-Jakob disease: patterns of worldwide occurrence and the significance of familial and sporadic clustering. Ann Neurol 1979;5:177-188
10. Saiz A, Arpa J, Sagasta A, et al. Autoantibodies to glutamic acid decarboxylase in three patients with cerebellar ataxia, late-onset insulin-dependent diabetes mellitus, and polyendocrine autoimmunity. Neurology 1997;49:1026-1030
11. Greenberg SM, Vonsattel JPG, Stakes JW, et al. The clinical spectrum of cerebral amyloid angiopathy: presentations without lobar hemorrhage. Neurology 1993;43:2073-2079
12. Alamowitch S, Graus F, Uchuya M, et al. Limbic encephalitis and small cell lung cancer: clinical and immunological features. Brain 1997;120:923-928
13. Voltz R, Gultekin SH, Rosenfeld MR, et al. A serologic marker of paraneoplastic limbic and brain-stem encephalitis in patients with testicular cancer. N Engl J Med 1999;340:1788-1795
14. Mason WP, Graus F, Lang B, et al. Small-cell lung cancer, paraneoplastic cerebellar degeneration and the Lambert-Eaton myasthenic syndrome. Brain 1997;120:1279-1300
15. Hammak JE, Kotanides H, Rosenblum MK, Posner JB. Paraneoplastic cerebellar degeneration, II. Clinical and immunologic findings in 21 patients with Hodgkin's disease. Neurology 1992;42:1938-1943