Regulation by long-chain fatty acids of the expression of cholesteryl ester transfer protein in HepG2 cells

Lipids

Volumn 36, Issue 4, 2001, Pages 401-406

  Hirano, Reiko ^a,b   Igarashi, Osamu ^c   Kondo, Kazuo ^c   Itakura, Hiroshige ^b   Matsumoto, Akiyo ^b  

^a NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^b NATIONAL INSTITUTE OF HEALTH AND NUTRITION   (Japan)

^c OCHANOMIZU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHOLESTEROL; FATTY ACIDS; METABOLISM; PROTEINS; RNA;

HIGH DENSITY LIPOPROTEINS (HDL);

LIPIDS;

ARACHIDONIC ACID; CHOLESTEROL ESTER TRANSFER PROTEIN; DOCOSAHEXAENOIC ACID; HIGH DENSITY LIPOPROTEIN; ICOSAPENTAENOIC ACID; LIPOPROTEIN; LONG CHAIN FATTY ACID; MESSENGER RNA; SATURATED FATTY ACID; UNSATURATED FATTY ACID;

ARTICLE; CELL STRAIN HEPG2; CHEMICAL STRUCTURE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LIPOPROTEIN BLOOD LEVEL; PROTEIN SYNTHESIS;

EID: 0035039173     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-001-0735-3     Document Type: Article

References (39)

1. Barter, P.J., Gorjatschko, L., and Calvert, G.D. (1980) Net Mass Transfer of Esterified Cholesterol from Human Low Density Lipoproteins to Very Low Density Lipoproteins Incubated in vitro, Biochim. Biophys. Acta 619, 436-439.
2. Inazu, A., Brown, M.L., Hesler, C.B., Agellon, L.B., Koizumi, J., Takata, K., Maruhama, Y., Mabuchi, H., and Tall, A.R. (1990) Increased High-Density Lipoprotein Levels Caused by a Common Cholesteryl-Ester Transfer Protein Gene Mutation, N. Engl. J. Med. 323, 1234-1238.
3. Marcel, Y.L., McPherson, R., Hogue, M., Czarnecka, H., Zawadzki, Z., Weech, P.K., Whitlock, M.E., Tall, A.R., and Milne, R.W. (1990) Distribution and Concentration of Cholesteryl Ester Transfer Protein in Plasma of Normolipemic Subjects, J. Clin. Invest. 85, 10-17.
4. Ritsch, A., Auer, B., Foger, B., Schwarz, S., and Patsch, J.R. (1993) Polyclonal Antibody-Based Immunoradiometric Assay for Quantification of Cholesteryl Ester Transfer Protein, J. Lipid Res. 34, 673-679.
5. Drayna, D., Jarnagin, A.S., McLean, J., Henzel, W., Kohr, W., Fielding, C., and Lawn, R. (1987) Cloning and Sequencing of Human Cholesteryl Ester Transfer Protein cDNA, Nature 327, 631-634.
6. Jiang, X.C., Moulin, P., Quinet, E., Goldberg, I.J., Yacoub, L.K., Agellon, L.B., Compton, D., Schnitzer-Polokoff, R., and Tall, A.R. (1991) Mammalian Adipose Tissue and Muscle Are Major Sources of Lipid Transfer Protein mRNA, J. Biol. Chem. 266, 4631-4639.
7. Nagashima, M., McLean, J.W., and Lawn, R.M. (1988) Cloning and mRNA Tissue Distribution of Rabbit Cholesteryl Ester Transfer Protein, J. Lipid Res. 29, 1643-1649.
8. Pape, M.E., Rehberg, E.F., Marotti, K.R., and Melchior, G.W. (1991) Molecular Cloning, Sequence, and Expression of Cynomolgus Monkey Cholesteryl Ester Transfer Protein. Inverse Correlation Between Hepatic Cholesteryl Ester Transfer Protein mRNA Levels and Plasma High Density Lipoprotein Levels, Arterioscler. Thromb. 11, 1759-1771.
9. Tall, A.R. (1993) Plasma Cholesteryl Ester Transfer Protein, J. Lipid Res. 34, 1255-1274.
10. Lagrost, L. (1994) Regulation of Cholesteryl Ester Transfer Protein (CETP) Activity: Review of in vitro and in vivo Studies, Biochim. Biophvs. Acta 1215, 209-236.
11. Quinet, E.M., Agellon, L.B., Kroon, P.A., Marcel, Y.L., Lee, Y.C., Whitlock, M.E., and Tall, A.R. (1990) Atherogenic Diet Increases Cholesteryl Ester Transfer Protein Messenger RNA Levels in Rabbit Liver, J. Clin. Invest. 85, 357-363.
12. Leaf, A., and Weber, P.C. (1988) Cardiovascular Effects of n-3 Fatty Acids, N. Engl. J. Med. 318, 549-557.
13. Bagdade, J.D., Ritter, M.C., Davidson, M., and Subbaiah, P.V. (1992) Effect of Marine Lipids on Cholesteryl Ester Transfer and Lipoprotein Composition in Patients with Hypercholesterolemia, Arterioscler. Thromb. 12, 1146-1152.
14. Schwab, U.S., Maliranta, H.M., Sarkkinen, E.S., Savolainen, M.J., Kesaniemi, Y.A., and Uusitupa, M.I. (1996) Different Effects of Palmitic and Stearic Acid-Enriched Diets on Serum Lipids and Lipoproteins and Plasma Cholesteryl Ester Transfer Protein Activity in Healthy Young Women, Metabolism 45, 143-149.
15. van Tol, A., Zock, P.L., van Gent, T., Scheek, L.M., and Katan, M.B. (1995) Dietary trans Fatty Acids Increase Serum Cholesterylester Transfer Protein Activity in Man, Atherosclerosis 115, 129-134.
16. Khosla, P., Hajri, T., Pronczuk, A., and Hayes, K.C. (1997) Replacing Dietary Palmitic Acid with Elaidic Acid (t-C 18:1 Δ9) Depresses HDL and Increases CETP Activity in Cebus Monkeys, J. Nutr. 127, 531S-536S.
17. Faust, R.A., and Albers, J.J. (1988) Regulated Vectorial Secretion of Cholesteryl Ester Transfer Protein (LTP-I) by the CaCo-2 Model of Human Enterocyte Epithelium, J. Biol. Chem. 263, 8786-8789.
18. Sperker, B., Mark, M., and Budzinski, R.M. (1993) The Expression of Human Plasma Cholesteryl-Ester-Transfer Protein in HepG2 Cells Is Induced by Sodium Butyrate. Quantification of Low mRNA Levels by Polymerase Chain Reaction, Eur. J. Biochem. 218, 945-950.
19. Lagrost, L., and Barter, P.J. (1991) Effects of Various Non-esterified Fatty Acids on the Particle Size Redistribution of High Density Lipoproteins Induced by the Human Cholesteryl Ester Transfer Protein, Biochim. Biophys. Acta 1082, 204-210.
20. Lagrost, L., and Barter, P.J. (1991) Effects of Various Non-esterified Fatty Acids on the Transfer of Cholesteryl Esters from HDL to LDL Induced by the Cholesteryl Ester Transfer Protein, Biochim. Biophys. Acta 1085, 209-216.
21. Chomczynski, P., and Sacchi, N. (1987) Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction, Anal. Biochem. 162, 156-159.
22. Kiyohara, T., Kiriyama, R., Zamma, S., Inazu, A., Koizumi, J., Mabuchi, H., and Chichibu, K. (1998) Enzyme Immunoassay for Cholesteryl Ester Transfer Protein in Human Serum, Clin. Chim. Acta 271, 109-118.
23. Folch, J., Lees, M., and Sloane Stanley, G.H. (1957) A Simple Method for the Isolation and Purification of Total Lipids from Animal Tissues, J. Biol. Chem. 226, 497-509.
24. Fujiyama-Fujiwara, Y., Ohmori, C., and Igarashi, O. (1989) Metabolism of γ-Linolenic Acid in Primary Cultures of Rat Hepatocytes and in Hep G2 Cells, J. Nutr. Sci. Vitaminol. 35, 597-611.
25. Faust, R.A., and Albers, J.J. (1987) Synthesis and Secretion of Plasma Cholesteryl Ester Transfer Protein by Human Hepatocarcinoma Cell Line, HepG2, Arteriosclerosis 7, 267-275.
26. Agellon, L.B., Zhang, P., Jiang, X.C., Mendelsohn, L., and Tall, A.R. (1992) The CCAAT/Enhancer-Binding Protein Transactivates the Human Cholesteryl Ester Transfer Protein Gene Promoter, J. Biol. Chem. 267, 22336-22339.
27. Raclot, T., Groscolas, R., Langin, D., and Ferre, P. (1997) Site-Specific Regulation of Gene Expression by n-3 Polyunsaturated Fatty Acids in Rat White Adipose Tissues, J. Lipid Res. 38, 1963-1972.
28. Auwerx, J., Schoonjans, K., Fruchart, J.C., and Staels, B. (1996) Transcriptional Control of Triglyceride Metabolism: Fibrates and Fatty Acids Change the Expression of the LPL and Apo C-III Genes by Activating the Nuclear Receptor PPAR, Atherosclerosis 124 (Suppl.), S29-S37.
29. Amri, E.Z., Teboul, L., Vannier, C., Grimaldi, P.A., and Ailhaud, G. (1996) Fatty Acids Regulate the Expression of Lipoprotein Lipase Gene and Activity in Preadipose and Adipose Cells, Biochem. J. 314, 541-546.
30. Skretting, G., Gjernes, E., and Prydz, H. (1997) Sodium Butyrate Inhibits the Expression of the Human Lecithin:Cholesterol Acyltransferase Gene in HepG2 Cells by a Post-Transcriptional Mechanism, FEBS Lett. 404, 105-110.
31. Subbaiah, P.V., Subramanian, V.S., and Liu, M. (1998) Trans Unsaturated Fatty Acids Inhibit Lecithin:Cholesterol Acyltransferase and Alter Its Positional Specificity, J. Lipid Res. 39, 1438-1447.
32. Ritsch, A., Doppler, W., Pfeifhofer, C., Sandhofer, A., Bodner, J., and Patsch, J.R. (1999) Cholesteryl Ester Transfer Protein Gene Expression Is Not Specifically Regulated by CCAAT/Enhancer-Binding Protein in HepG2-cells, Atherosclerosis 146, 11-18.
33. Gaudet, F., and Ginsburg, G.S. (1995) Transcriptional Regulation of the Cholesteryl Ester Transfer Protein Gene by the Orphan Nuclear Hormone Receptor Apolipoprotein AI Regulatory Protein-1, J. Biol. Chem. 270, 29916-29922.
34. Chouinard, R.A., Jr., Luo, Y., Osborne, T.F., Walsh, A., and Tall, A.R. (1998) Sterol Regulatory Element Binding Protein-1 Activates the Cholesteryl Ester Transfer Protein Gene in vivo but Is Not Required for Sterol Up-regulation of Gene Expression, J. Biol. Chem. 273, 22409-22414.
35. Gauthier, B., Robb, M., Gaudet, F., Ginsburg, G.S., and McPherson, R. (1999) Characterization of a Cholesterol Response Element (CRE) in the Promoter of the Cholesteryl Ester Transfer Protein Gene: Functional Role of the Transcription Factors SREBP-1a, -2, and YY1, J. Lipid Res. 40, 1284-1293.
36. Kim, H.J., Takahashi, M., and Ezaki, O. (1999) Fish Oil Feeding Decreases Mature Sterol Regulatory Element-Binding Protein 1 (SREBP-1) by Down-Regulation of SREBP-1c mRNA in Mouse Liver. A Possible Mechanism for Down-Regulation of Lipogenic Enzyme mRNAs, J. Biol. Chem. 274, 25892-25898.
37. Yahagi, N., Shimano, H., Hasty, A.H., Amemiya-Kudo, M., Okazaki, H., Tamura, Y., Iizuka, Y., Shionoiri, F., Ohashi, K., Osuga, J., et al. (1999) A Crucial Role of Sterol Regulatory Element-Binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids, J. Biol. Chem. 274, 35840-35844.
38. Sammett, D., and Tall, A.R. (1985) Mechanisms of Enhancement of Cholesteryl Ester Transfer Protein Activity by Lipolysis, J. Biol. Chem. 260, 6687-6697.
39. Nishida, H.I., Arai, H., and Nishida, T. (1993) Cholesterol Ester Transfer Mediated by Lipid Transfer Protein as Influenced by Changes in the Charge Characteristics of Plasma Lipoproteins, J. Biol. Chem. 268, 16352-16360.