Establishment of an oral squamous cell carcinoma cell line(NOS-1) exhibiting amplification of the erbB-1 oncogene and point mutation of p53 tumor suppressor gene: Its biological characteristics and animal model of local invasion by orthotopic transplantation of the cell line

Oral Oncology

Volumn 37, Issue 4, 2001, Pages 386-392

  Ji, Z W ^a   Oku, N ^a   Umeda, M ^a   Komori, T ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

ErbB 1 oncogene; Human squamous cell carcinoma cell line; Mouth neoplasms; p53 tumor suppressor gene; Xenograft tumors

Indexed keywords

ANTIBIOTIC G 418; EPIDERMAL GROWTH FACTOR RECEPTOR; MUTANT PROTEIN; PROTEIN ERB B1; PROTEIN P53; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CANCER TRANSPLANTATION; CASE REPORT; CELL STRUCTURE; CODON; CONTROLLED STUDY; ELECTRON MICROSCOPY; FIBROBLAST; GENE AMPLIFICATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MOUTH CARCINOMA; NONHUMAN; NUDE MOUSE; ONCOGENE; POINT MUTATION; PRIORITY JOURNAL; RECEPTOR GENE; SQUAMOUS CELL CARCINOMA; TONGUE; TUMOR SUPPRESSOR GENE;

ANIMALS; BLOTTING, SOUTHERN; CARCINOMA, SQUAMOUS CELL; GENE AMPLIFICATION; GENES, ERBB-1; GENES, ERBB-2; GENES, P53; HUMANS; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-MYC; SEQUENCE ANALYSIS, DNA; TUMOR CELLS, CULTURED;

EID: 0035033076     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1368-8375(00)00088-9     Document Type: Article

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