Prostate-specific antigen and human glandular kallikrein 2 are markedly elevated in urine of patients with polycystic ovary syndrome

Journal of Clinical Endocrinology and Metabolism

Volumn 86, Issue 4, 2001, Pages 1558-1561

  Obiezu, Chrisitna V ^a,b   Scorilas, Andreas ^a,b   Magklara, Angeliki ^a,b   Thornton, Melvin H ^c   Wang, Chun Y ^c   Stanczyk, Frank Z ^c   Diamandis, Eleftherios P ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANEDIOL; KALLIKREIN; PROSTATE SPECIFIC ANTIGEN; SERINE PROTEINASE; TUMOR MARKER;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; FEMALE; HUMAN; HYPERANDROGENISM; IMMUNOASSAY; OVARY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; URINALYSIS;

EID: 0035031409     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.86.4.7378     Document Type: Article

References (36)

1. Polycystic ovary syndrome
2. Polycystic ovaries - A common finding in normal women
3. Insulin and the polycystic ovary syndrome
4. Circulating ovarian IGF binding proteins: Potential roles in normo-ovulatory cycles and in polycystic ovary syndrome
5. Observation in favor of normal early follicle development and disturbed dominant follicle selection in polycystic ovary syndrome
6. Regulation of androgen production in cultured human theca cells by insulin-like growth factor I and insulin
7. Insulin-like growth factors, insulin-like factor binding proteins and ovarian androgen production
8. Elevated serum levels of free insulin-like growth factor I in polycystic ovary syndrome
9. Role of hyperinsulinemia in the pathogenesis of the polycystic ovary syndrome and clinical implications
10. Insulin resistance and the polycystic ovary syndrome: Mechanism and implications in pathogenesis
11. 17β-oestradiol, androstenedione and inhibin levels in fluid from individual follicles of normal and polycystic ovaries, and in ovaries from androgen treated female to male transsexuals
12. A prostate antigen in sera of prostate cancer patients
13. Prostate-specific antigen: A critical assessment of the most useful tumor marker for adenocarcinoma of the prostate
14. New biological functions of prostate-specific antigen?
15. Nonprostatic sources of prostate-specific antigen
16. Prostate-specific antigen in the breast
17. Prostate-specific antigen in breast cancer, benign breast disease and normal breast tissue
18. Prognostic value of plasma prostate-specific antigen after megestrol acetate treatment in patients with metastatic breast carcinoma
19. In prostatism patients the ratio of human glandulary kallikrein to free PSA improves the discrimination between prostate cancer and benign hyperplasia within the diagnostic "gray zone" of total PSA 4 to 10 ng/mL
20. Human glandular kallikrein in breast milk, amniotic fluid, and breast cyst fluid
21. Steroid hormone regulation of prostate-specific antigen gene expression in breast cancer
22. Prostate-specific antigen production by breast tumors after induction with oral contraceptives
23. Breast tissues in transsexual women - A nonprostatic source of androgen up-regulated production of prostate-specific androgen
24. Serum and urinary prostate-specific antigen and urinary human glandular kallikrein concentration are significantly increased after testosterone administration in female-to-male transsexuals
25. Prostate-specific antigen in female serum, a potential new marker of androgen excess
26. The increased circulating prostate-specific antigen concentrations in women with hirsutism do not respond to acute changes in adrenal or ovarian function
27. Extraprostatic production of prostate-specific antigen is trader hormonal control
28. Homology between the female paraurethral Skene's gland and the prostate: Immunohistochemical demonstration
29. The "female prostate." Location, morphology, immunohistochemical characteristics and significance
30. Hirsutism: Implications, etiology and management
31. Ultrasensitive detection of prostate-specific antigen by a time-resolved immunofluorometric assay and the Immulite® Immunochemiluminescent third generation assay: Potential applications in prostate and breast cancers
32. Development of an ultrasensitive immunoassay for human glandular kallikrein with no cross reactivity from prostate-specific antigen
33. Differential steroid hormone regulation of human glandular kallikrein (hΚ2) and prostate-specific antigen (PSA) in breast cancer cell lines
34. Do hyperandrogenic women with normal menses have polycystic ovary syndrome?
35. Serum levels of 3α-androstanediol glucuronide in hirsute and non-hirsute women
36. Polycystic ovary syndrome: The spectrum of the disorder in 1741 patients