Meal-related stimuli differentially induce c-Fos activation in the nucleus of the solitary tract

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 280, Issue 5 49-5, 2001, Pages

  Emond, Michael ^a,b   Schwartz, Gary J ^a,c   Moran, Timothy H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF REGINA   (Canada)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Brain gut communication; Dorsal hindbrain; Gastrointestinal tract; Satiety

Indexed keywords

PROTEIN C FOS;

ANIMAL EXPERIMENT; ARTICLE; FOOD INTAKE; GENE ACTIVATION; IMMUNOREACTIVITY; MALE; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SOLITARY TRACT NUCLEUS;

EID: 0035026368     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.2001.280.5.r1315     Document Type: Article

References (21)

1. Appia F, Ewart WR, Pittman BS, and Wingate DL. Convergence of sensory information from abdominal viscera in the rat brainstem. Am J Physiol Gastrointest Liver Physiol 251: G169-G175, 1986.
2. Barber WD and Burks TF. Brain stem response to phasic gastric distension. Am J Physiol Gastrointest Liver Physiol 245: G242-G248, 1983.
3. Bonaz B, DeGiorgio R, and Tache Y. Peripheral bombesin induces c-fos protein in the rat brain. Brain Res 600: 353-357, 1993.
4. Emond MH and Weingarten HP. Fos-like immunoreactivity in vagal and hypoglossal nuclei in different feeding states a quantitative study. Physiol Behav 58: 459-465, 1995.
5. Ewart WR and Wingate DL. Central representation of arrival of nutrient in the duodenum. Am J Physiol Gastrointest Liver Physiol 246: G750-G756, 1984.
6. Fraser KA and Davison JS. Cholecystokinin induced c-fos expression in the rat brainstem is influenced by vagal nerve integrity. Exp Physiol 77: 225-228, 1992.
7. Fraser KA and Davison JS. Meal-induced c-fos expression in brain stem is not dependent on cholecystokinin release. Am J Physiol Regulatory Integrative Comp Physiol 265: R235-R239, 1993.
8. Fraser KA, Raizada E, and Davison JS. Oral-pharyngeal-esophageal and gastric cues contribute to meal-induced c-fos expression. Am J Physiol Regulatory Integrative Comp Physiol 268: R223-R230, 1995.
9. Harrer MI and Travers SP. Topographic organization of Fos-like immunoreactivity in the rostral nucleus of the solitary tract evoked by gustatory stimulation with sucrose and quinine. Brain Res 711: 125-137, 1996.
10. Li B-H and Rowland NE. Peripherally and centrally administered bombesin induce c-fos immunoreactivity in different brain regions in rats. Regul Pept 62: 167-172, 1996.
11. Mathis C, Moran TH, and Schwartz GJ. Load-sensitive rat gastric vagal afferents encode volume but not gastric nutrients. Am J Physiol Regulatory Integrative Comp Physiol 274: R280-R286, 1998.
12. Paxinos G and Watson C. The Rat Brain in Stereotaxic Coordinates. San Diego, CA: Academic, 1986.
13. Phifer CB and Berthoud H-R. Duodenal nutrient infusions differentially affect sham feeding and Fos expression in rat brain stem. Am J Physiol Regulatory Integrative Comp Physiol 274: R1725-R1733, 1998.
14. Rinaman L, Baker EA, Hoffman GE, Stricker EM, and Verbalis JG. Medullary c-fos activation in rats after ingestion of a satiating meal. Am J Physiol Regulatory Integrative Comp Physiol 275: R262-R268, 1998.
15. Rinaman L, Verbalis JG, Stricker EM, and Hoffman GE. Distribution and neurochemical phenotypes of caudal medullary neurons activated to express c-Fos following peripheral administration of cholecystokinin. J Comp Neurol 338: 475-490, 1993.
16. Schwartz GJ and Moran TH. Subdiaphragmatic vagal afferent integration of meal-related gastrointestinal signals. Neurosci Biobehav Rev 20: 47-56, 1996.
17. Schwartz GJ and Moran TH. Duodenal nutrient exposure elicits nutrient specific gut motility and vagal afferent signals in rat. Am J Physiol Regulatory Integrative Comp Physiol 274: R1236-R1242, 1998.
18. Traub RJ, Sengupta JN, and Gebhart GF. Differential c-fos expression in the nucleus of the solitary tract and spinal cord following noxious gastric distention in the rat. Neuroscience 74: 873-884, 1966.
19. Wang L, Cardin S, Martinez V, Tache Y, and Lloyd KCK. Duodenal loading with glucose induces Fos expression in rat brain: selective blockade by devazepide. Am J Physiol Regulatory Integrative Comp Physiol 277: R667-R674, 1999.
20. Willing AE and Berthoud H-R. Gastric distension-induced c-fos expression in catecholaminergic neurons of rat dorsal vagal complex. Am J Physiol Regulatory Integrative Comp Physiol 272: R59-R67, 1997.
21. Zittel TT, DeGiorgio R, Sternini C, and Raybould HE. Fos protein expression in the nucleus of the solitary tract in response to intestinal nutrients in awake rats. Brain Res 663: 266-270, 1994.