Free-choice alcohol consumption in mice after application of the appetite regulating peptide Leptin

Alcoholism: Clinical and Experimental Research

Volumn 25, Issue 5, 2001, Pages 787-789

  Kiefer, Falk ^a   Jahn, H ^a   Wolf, K ^a   Kampf P ^a   Knaudt, K ^a   Wiedemann, K ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Addiction; Alcoholism; Craving; Leptin; Mice

Indexed keywords

ALCOHOL; LEPTIN; SODIUM CHLORIDE;

ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENERGY EXPENDITURE; FOOD INTAKE; HABITUATION; MALE; MOTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA;

EID: 0035025768     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2001.tb02280.x     Document Type: Article

References (18)

1. Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P (1995) Recombinant mouse ob protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549.
2. Fulton S, Woodside B, Shizgal P (2000) Modulation of brain reward circuitry by leptin. Science 287:125-128.
3. Grant KA (1990) Behavioral animal models in alcohol abuse research. Alc Health Res World 14:187-192.
4. Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM (1995) Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546.
5. Inui A (1999) Feeding and body-weight regulation by hypothalamic neuropeptides - mediation of the actions of leptin. Trends Neurosci 22:62-67.
6. Junghanns K, Veltrup C, Wetterling T (2000) Craving shift in chronic alcoholics. Eur Addict Res 6:64-70.
7. Kiefer F, Jahn H, Kellner M, Naber D, Wiedemann K (2001) Leptin as a possible modulator of craving for alcohol. Arch Gen Psychiat, in press.
8. Maffei M, Halaas J, Ravussin E, Pratley RE, Lee GH, Zhang Y, Fei H, Kim S, Lallone R, Ranganathan S (1995) Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nature Med 1:1155-1161.
9. Mantzoros CS (1999) Leptin and the hypothalamus: Neuroendocrine regulation of food intake. Mol Psychiat 4:8-12.
10. Mizuno TM, Kleopoulos SP, Bergen HT, Roberts JL, Priest CA, Mobbs CV (1998) Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting in ob/ob and db/db mice, but is stimulated by leptin. Diabetes 47:294-297.
11. Morimoto T, Yamamoto Y, Mobarakeh JI, Yanai K, Watanabe T, Yamatodani A (1999) Involvement of the histaminergic system in leptin-induced suppression of food intake. Physiol Behav 67:679-683.
12. Overstreet DA, B.Kampov-Polevoy AB, Rezvani AH, Murelle L, Halikas JA, Janowsky DS (1993) Saccharin intake predicts alcohol intake in genetically heterogenous rats as well as different rat strains. Alcohol Clin Exp Res 17:366-369.
13. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F (1995) Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543.
14. Schwartz MW, Seeley RJ, Woods SC, Weigle DS, Campfield LA, Burn P, Baskin DG (1997) Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus. Diabetes 46:2119-2123.
15. Sinclair JD, Kampov-Polevoy AB, Stewart R, Li T-K (1992) Taste preference in rat lines selected for low and high alcohol consumption. Alcohol 9:155-160.
16. Spanagel R, Holter SM (1999) Long-term alcohol self-administration with repeated alcohol deprivation phases: An animal model of alcoholism? Alcohol Alcohol 34:231-243.
17. Spinedi E, Gaillard RC (1998) Regulatory loop between the hypothalamo-pituitary-adrenal(HPA) axis and circulating leptin: A physiological role of ACTH. Endocrinol 139:1416-1420.
18. Wand GS, Schumann H (1998) Relationship between Plasma Adrenocorticotropin, Hypothalamic Opioid Tone, and Plasma Leptin. J Clin Endocrinol Metabol 83:2138-2142.