Ebola virus glycoprotein demonstrates differential cellular localization in infected cell types of nonhuman primates and guinea pigs

Archives of Pathology and Laboratory Medicine

Volumn 125, Issue 5, 2001, Pages 625-630

  Steele, Keith ^a,b   Crise, Bruce ^a,c   Kuehne, Ana ^a   Kell, Wayne ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^c SAIC FREDERICK INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS GLYCOPROTEIN; VIRUS PROTEIN; VIRUS RNA;

ADRENAL CORTEX CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TYPE; CELLULAR DISTRIBUTION; EBOLA VIRUS; EPITHELIUM CELL; FIBROBLAST; GENE PROBE; GUINEA PIG; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIVER CELL; MACROPHAGE; MONOCYTE; NONHUMAN; PRIMATE; PROTEIN LOCALIZATION; RETICULUM CELL; THECA CELL; VERO CELL; VIRUS HEMORRHAGIC FEVER;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; GUINEA PIGS; HEMORRHAGIC FEVER, EBOLA; IN SITU HYBRIDIZATION; MACACA MULATTA; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MONOCYTES; NUCLEOPROTEINS; RNA, MESSENGER; TISSUE DISTRIBUTION; VERO CELLS; VIRAL CORE PROTEINS; VIRAL MATRIX PROTEINS;

EID: 0035024976     PISSN: 00039985     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Centers for Disease Control and Prevention. Update: outbreak of Ebola viral hemorrhagic fever - Zaire, 1995. MMWR Morb Mortal Wkly Rep. 1995;44:468-469,475.
2. Bres P. The epidemic of Ebola haemorrhagic fever in Sudan and Zaire, 1976: introductory note. Bull World Health Organ. 1978;56:245.
3. Peters C, Sanchez A, Rollin P, Ksiazek T, Murphy F. Filoviridae: Marburg and Ebola viruses. In: Fields B, Knipe D, Howley P, eds. Fields Virology. 3rd ed. Philadelphia, Pa: Lippincott-Raven; 1996:1161-1177.
4. Jahrling PB, Geisbert TW, Dalgard DW, et al. Preliminary report: isolation of Ebola virus from monkeys imported to USA. Lancet. 1990;335:502-505.
5. Geisbert TW, Jahrling PB, Hanes MA, Zack PM. Association of Ebola-related Reston virus particles and antigen with tissue lesions of monkeys imported to the United States. J Comp Pathol. 1992;106:137-152.
6. Le Guenno B, Formentry P, Wyers M, Gounon P, Walker F, Boesch C. Isolation and partial characterisation of a new strain of Ebola virus. Lancet. 1995; 345:1271-1274.
7. Connolly BM, Steele KE, Davis KJ, et al. Pathogenesis of experimental Ebola virus infection in guinea pigs. J Infect Dis. 1999;179(suppl 1):S203-S217.
8. Bray M, Davis K, Geisbert T, Schmaljohn C, Huggins J. A mouse model for evaluation of prophylaxis and therapy of Ebola hemorrhagic fever. J Infect Dis. 1998;178:651-661.
9. Vogel P, Connolly B, Abplanalp D, et al. Pathology of experimental EbolaZaire (Mayinga) virus infection transmitted to guinea pigs by oral, conjunctival and tonsillar routes. Cell Vision. 1997;4:298-307.
10. Ryabchikova E, Kolesnikova L, Smolina M, et al. Ebola virus infection in guinea pigs: presumable role of granulomatous inflammation in pathogenesis. Arch Virol. 1996;141:909-921.
11. Jaax NK, Davis KJ, Geisbert TJ, et al. Lethal experimental infection of rhesus monkeys with Ebola-Zaire (Mayinga) virus by the oral and conjunctiva route of exposure. Arch Pathol Lab Mod. 1996;120:140-155.
12. Davis KJ, Anderson AO, Geisbert TW, et al. Pathology of experimental Ebola virus infection in African green monkeys. Involvement of fibroblastic reticular cells. Arch Pathol Lab Mod. 1997;121:805-819.
13. Baskerville A, Fisher-Hoch SP, Neild GH, Dowsett AB. Ultrastructural pathology of experimental Ebola haemorrhagic fever virus infection. J Pathol. 1985; 147:199-209.
14. Sanchez A, Kiley MP, Holloway BP, Auperin DD. Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus. Virus Res. 1993;29:215-240.
15. Sanchez A, Trappier SG, Mahy BW, Peters CJ, Nichol ST. The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing. Proc Natl Acad Sci U S A. 1996;93:3602-3607.
16. Sanchez A, Yang ZY, Xu L, Nabel GJ, Crews T, Peters CJ. Biochemical analysis of the secreted and virion glycoproteins of Ebola virus. J Virol. 1998;72: 6442-6447.
17. Takada A, Robison C, Goto H, et al. A system for functional analysis of Ebola virus glycoprotein. Proc Natl Acad Sci U S A. 1997;94:14764-14769.
18. Wool-Lewis RJ, Bates P. Characterization of Ebola virus entry by using pseudotyped viruses: identification of receptor-deficient cell lines. J Virol. 1998; 72:3155-3160.
19. Volchkov VE, Volchkova VA, Slenczka W, Klenk HD, Feldmann H. Release of viral glycoproteins during Ebola virus infection. Virology. 1998;245:110-119.
20. Tilson MD, Ozsvath KJ, Hirose H, Xia S, Lahita R. A novel hypothesis to explain the hemorrhagic and connective tissue manifestations of Ebola virus infection. Clin Immunol Immunopathol. 1996;81:303-306.
21. Kadota JL, Cianciolo GJ, Snyderman R. A synthetic peptide homologous to retroviral transmembrane envelope proteins depresses protein kinase C mediated lymphocyte proliferation and directly inactivated protein kinase C: a potential mechanism for immunosuppression. Microbiol Immunol. 1991;35:443-459.
22. Volchkov VE, Becker S, Volchkova VA, et al. GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases. Virology. 1995;214:421-430.
23. Kell WM, Sheridan-Cuddy LC, Vogel P. A nonisotopic in situ hybridization assay with digoxigenin-labeled DNA probes to detect viral RNA in paraffin-embedded tissues. Cell Vision. 1997;4:339-346.