A comparison of the efficacy and safety of a half dose of fluticasone propionate with beclamethasone dipropionate and budesonide in childhood asthma

Journal of Asthma

Volumn 38, Issue 3, 2001, Pages 229-237

  Karakoç, Fazilet ^a,b   Karadag, B ^a   Kut, A ^a   Ersu, R ^a   Bakac S ^a   Cebeci, D ^a   Dagli, E ^a  

^a MARMARA UNIVERSITY   (Turkey)

^b Barbaros Mah Bahar Sitesi ^*  (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE DIPROPIONATE; BUDESONIDE; FLUTICASONE PROPIONATE;

ADOLESCENT; ARTICLE; ASTHMA; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DRUG EFFICACY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HYDROCORTISONE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PEAK EXPIRATORY FLOW; PRESCHOOL CHILD; SCHOOL CHILD; SIDE EFFECT;

ADMINISTRATION, INHALATION; ANDROSTADIENES; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; ASTHMA; BECLOMETHASONE; BUDESONIDE; CHILD; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; RESPIRATORY FUNCTION TESTS; TIME FACTORS;

EID: 0035024660     PISSN: 02770903     EISSN: None     Source Type: Journal    
DOI: 10.1081/JAS-100000110     Document Type: Article

References (38)

1. Guidelines for the Diagnosis and Management of Asthma. Expert Panel Report II, NIH Publication 97-4051; National Institutes of Health, National Heart, Lung, and Blood Institute: Bethesda, MD, 1997.
2. Van Essen-Zandvliet, E.E.; Hughes, M.D.; Waalkens, H.J.; Duiverman, J. Effects of 22 Months of Treatment with Inhaled Corticosteroids and/or Beta-2 Agonists on Lung Function, Airway Responsiveness. and Symptoms in Children with Asthma. Am. Rev. Respir. Dis. 1992, 146, 547.
3. Lipworth, B.J. Systemic Adverse Effects of Inhaled Corticosteroid Therapy: A Systematic Review and Meta-Analysis. Arch. Intern. Med. 1999, 159, 941.
4. Harding, S.M. The Human Pharmacology of Fluticasone Propionate. Respir. Med. 1990, 84, 25.
5. Gustafsson, P.; Tsanakas, J.; Gold, M.; Primhak, R. Fluticasone Propionate 200 μG/Day with Inhaled Beclomethasone Dipropionate 400 μG/Day in Mild and Moderate Asthma. Arch. Dis. Child. 1993, 69, 206.
6. Fitzgerald, D.; Van Asperen, P.; Mellis, C.; Honner, M. Fluticasone Propionate 750 μG/Day Versus Beclomethasone Dipropionate 1500 μG/Day: Comparison of Efficacy and Adrenal Function in Paediatric Asthma. Thorax 1998, 53, 656.
7. Barnes, N.C.; Marone, G.; Di Maria, G.U.; Visser, S. A Comparison of Fluticasone Propionate, I mg Daily, with Beclomethasone Dipropionate, 2 mg Daily, in the Treatment of Severe Asthma. Eur. Respir. J. 1993, 6, 877.
8. Bootsma, G.P.; Dekhuijzen, P.N.R.; Festen, J.; Mulder, P.G.H. Comparison of Fluticasone Propionate and Beclomethasone Dipropionate on Direct and Indirect Measurements of Bronchial Hyperresponsiveness in Patients with Stable Asthma. Thorax 1995, 50, 1044.
9. Raphael, G.D.; Lanier, R.Q.; Baker, J.; Edwards, L. A Comparison of Multiple Doses of Fluticasone Propionate in Subjects with Persistent Asthma. J. Allergy Clin. Immunol. 1999, 103, 796.
10. Langdon, C.G.; Capsey, L.J. Fluticasone Propionate and Budesonide in Adult Asthmatics: A Comparison Using Dry-Powder Inhaler Devices. Br. J. Clin. Res. 1994, 5, 85.
11. Langdon, C.G.; Thompson, J. A Multicentre Study to Compare the Efficacy and Safety of Inhaled Fluticasone Propionate and Budesonide via Metered Dose Inhalers in Adults with Mild-Moderate Asthma. Br. J. Clin. Res. 1994, 5, 73.
12. Ferguson, A.C.; Spier, S.; Manjra, A.; Versteegh, G.A. Efficacy and Safety of High-Dose Inhaled Steroids in Children with Asthma: A Comparison of Fluticasone Propionate with Budesonide. J. Pediatr. 1999, 134, 422.
13. Williams, J.; Richards, K.A. Ease of Handling and Clinical Efficacy of Fluticasone Propionate Accuhaler/Diskus™ Inhaler Compared with the Turbohaler™ Inhaler in Paediatric Patients. Br. J. Clin. Pract. 1997, 51, 147.
14. Hoekx, J.C.M.; Hedlin, G.; Pedersen, W.; Sorva, R. Fluticasone Propionate Compared with Budesonide: A Double-Blind Trial in Asthmatic Children Using Powder Devices at a Dosage of 400 μg. Day. Eur. Respir. J. 1996, 9, 2263.
15. Agertoft, L.; Pedersen, S. A Randomized, Double-Blind Dose Reduction Study to Compare the Minimal Effective Dose of Budesonide Turbohaler and Fluticasone Propionate Diskhaler. J. Allergy Clin. Immunol. 1997, 99, 773.
16. Laird, N.M.; Ware, J.H. Random Effects Models for Longitudinal Data. Biometrika 1982, 51, 313.
17. Fabbri, L.; Burge, P.S.; Croonenborgh, L.; Warlies, F. Comparison of Fluticasone Propionate with Beclomethasone Dipropionate in Moderate to Severe Asthma Treated for One Year. Thorax 1993, 48, 817.
18. Barnes, N.C.; Hallett, C.; Harris, T.A.J. Clinical Experience with Fluticasone Propionate in Asthma: A Meta-Analysis of Efficacy and Systemic Activity Compared with Budesonide and Beclomethasone Dipropionate at Half the Microgram Dose or Less. Respir. Med. 1998, 92, 95.
19. Osmanliev, D.; Bowley, N.; Hunter, DM.; Pride, NB. Relation Between Tracheal Size and Forced Expiratory Volume in One Second in Young Men. Am. Rev. Respir. Dis. 1982, 126, 179.
20. Ferguson, A.C. Persisting Airway Obstruction in Asymptomatic Children with Asthma with Normal Peak Expiratory Flow Rates. J. Allergy Clin. Immunol. 1988, 82, 19.
21. Hyland, M.E.; Kenyon, C.A.P.; Allen, R. Diary Keeping in Asthma: Comparison of Written and Electronic Methods. Br. Med. J. 1993, 306, 487.
22. Lipworth, B.J.; Clark, D.J.; McFarlane, L.C. Adrenocortical Activity with Repeated Twice Daily Dosing of Fluticasone Propionate and Budesonide Given via a Large Volume Spacer to Asthmatic School Children. Thorax 1997, 52, 686.
23. Iolo, J.; Doull, M.; Nicholas, J.; Holgate, S.T. Growth of Prepubertal Children with Mild Asthma Treated with Inhaled Beclomethasone Dipropionate. Am. J. Respir. Crit. Care Med. 1995, 151, 1715.
24. Agertoft, L.; Pedersen, S. Short-Term Knemometry and Urine Cortisol Excretion in Children Treated with Fluticasone Propionate and Budesonide: A Dose Response Study. Eur. Respir. J. 1997, 10, 1507.
25. Nicolaizik, W.H.; Marchant, J.L.; Preece, M.A.; Warner, J.O. Endocrine and Lung Function in Asthmatic Children on Inhaled Corticosteroids. Am. J. Respir. Crit. Care Med. 1994, 150, 624.
26. Zimmerman, B.; Gold, M.; Wherrett, D.; Hanna, A.K. Adrenal Suppression in Two Patients with Asthma Treated with Low Doses of the Inhaled Steroid Fluticasone Propionate. J. Allergy Clin. Immunol. 1998, 101, 425.
27. Goldberg, S.; Algur, N.; Levi, M.; Brukheimer, E. Adrenal Supression Among Asthmatic Children Receiving Chronic Therapy with Inhaled Corticosteroid with and Without Spacer Device. Ann. Allergy Asthma Immunol. 1996, 76, 234.
28. Kargül, B.; Tanboǧa, I.; Ergeneli, S.; Karakoç, F.; Daǧli, E. Inhaler Medicament Effects on Saliva and Plaque pH in Asthmatic Children. J. Clin. Pediatr. Dent. 1998, 22, 137.
29. Risteli, L.; Risteli, J. Biochemical Markers of Bone Metabolism. Ann. Med. 1993, 25, 385.
30. Toogood, J.H.; Jennings, B.; Hodsman, A.B.; Baskerville, J. Effects of Dose and Dosing Schedule of Inhaled Budesonide on Bone Turnover. J. Allergy Clin. Immunol. 1991, 88, 572.
31. Pouw, E.M.; Prummel, M.F.; Oosting, H.; Roos, C.M. Beclomethasone Inhalation Decreases Serum Osteocalcin Concentrations. Br. Med. J. 1991, 16, 627.
32. Teelucksingh, S.; Padfield, PL.; Tibi, L.; Gough, K. Inhaled Corticosteroids, Bone Formation, and Osteocalcin. J. Allergy Clin. Immunol. 1991, 88, 572.
33. Wisniewski, A.F.; Lewis, S.A.; Green, D.J.; Maslanka, W. Cross Sectional Investigation of the Effects of Inhaled Corticosteroids on Bone Density and Bone Metabolism in Patients with Asthma. Thorax 1997, 52, 853.
34. Sorva, R.; Turpeinen, M.; Juntunen-Backman, K.; Karonen, S. Effects of Inhaled Budesonide on Serum Markers of Bone Metabolism in Children with Asthma. J. Allergy Clin. Immunol. 1992, 90, 808.
35. Hanania, N.; Kenneth, R.; Chapman, M.D.; William, C. Dose Related Decrease in Bone Density Among Asthmatic Patients Treated with Inhaled Corticosteroids. J. Allergy Clin. Immunol. 1995, 96, 571.
36. Bootsma, G.P.; Dekhujzen, P.N.R.; Festen, J.; Muldre, P.G.H. Fluticasone Propionate Does Not Influence Bone Metabolism in Contrast to Beclomethasone Dipropionate. Am. J. Respir. Crit. Care Med. 1996, 153, 924.
37. Ali, N.J.; Capewell, S.; Ward, M.J. Bone Turnover During High Dose Inhaled Corticosteroid Treatment. Thorax 1991, 46, 160.
38. Hughes, J.A.; Conry, B.G.; Male, S.M.; Eastell, R. One Year Prospective Open Study of the Effect of High Dose Inhaled Steroids, Fluticasone Propionate, and Budesonide on Bone Markers and Bone Mineral Density. Thorax 1999, 54, 223.