-
1
-
-
0342741643
-
Nasal tissue dosimetry -Issues and approaches for "Category I" gases: Areport on a meeting held in Research Triangle Park, NC, February 11-12, 1998
-
in press
-
Andersen, M. E., and Jarabek, A. M. (2000). Nasal tissue dosimetry -Issues and approaches for "Category I" gases: Areport on a meeting held in Research Triangle Park, NC, February 11-12, 1998. Inhal. Toxicol., in press.
-
(2000)
Inhal. Toxicol.
-
-
Andersen, M.E.1
Jarabek, A.M.2
-
2
-
-
0032720992
-
Dosimetric adjustment factors for methylmethacrylate derived from a steady-state analysis of a physiologically based clearance-extraction model
-
Andersen, M. E., Sarangapani, R., Frederick, C. B., and Kimbell, J. S. (1999). Dosimetric adjustment factors for methylmethacrylate derived from a steady-state analysis of a physiologically based clearance-extraction model. Inhal. Toxicol. 11, 899-926.
-
(1999)
Inhal. Toxicol.
, vol.11
, pp. 899-926
-
-
Andersen, M.E.1
Sarangapani, R.2
Frederick, C.B.3
Kimbell, J.S.4
-
3
-
-
0025981543
-
Physiologically based pharmacokinetic modeling with dichloromethane, its metabolite, carbon monoxide, and blood carboxyhemoglobin in rats and humans
-
Andersen, M. E., Clewell, H. J., III, Gargas, M. L., MacNaughton, M. G., Reitz, R. H., Nolan, R., and McKenna, M. (1991). Physiologically based pharmacokinetic modeling with dichloromethane, its metabolite, carbon monoxide, and blood carboxyhemoglobin in rats and humans. Toxicol. Appl. Pharmacol. 108, 14-27.
-
(1991)
Toxicol. Appl. Pharmacol.
, vol.108
, pp. 14-27
-
-
Andersen, M.E.1
Clewell, H.J.2
Gargas, M.L.3
MacNaughton, M.G.4
Reitz, R.H.5
Nolan, R.6
McKenna, M.7
-
4
-
-
0023158895
-
Physiologically-based pharmacokinetics and the risk assessment process for methylene chloride
-
Andersen, M. E., Clewell, H. J., III, Gargas, M. L., Smith, F. A., and Reitz, R. H. (1987). Physiologically-based pharmacokinetics and the risk assessment process for methylene chloride. Toxicol. Appl. Pharmacol. 87, 185-205.
-
(1987)
Toxicol. Appl. Pharmacol.
, vol.87
, pp. 185-205
-
-
Andersen, M.E.1
Clewell, H.J.2
Gargas, M.L.3
Smith, F.A.4
Reitz, R.H.5
-
5
-
-
0024202909
-
Reference dose (RfD): Description and use in health risk assessments
-
Barnes, D. G., and Dourson, M. L. (1988). Reference dose (RfD): Description and use in health risk assessments. Regul. Toxicol. Pharmacol. 8, 471-486.
-
(1988)
Regul. Toxicol. Pharmacol.
, vol.8
, pp. 471-486
-
-
Barnes, D.G.1
Dourson, M.L.2
-
6
-
-
0346453784
-
Harmonization: Developing consistent guidelines for applying mode of action and dosimetry information to cancer and noncancer risk assessment
-
Barton, H. A., Andersen, M. E., and Clewell, H. J., III (1998). Harmonization: Developing consistent guidelines for applying mode of action and dosimetry information to cancer and noncancer risk assessment. Hum. Ecol. Risk Assess. 4, 75-115.
-
(1998)
Hum. Ecol. Risk Assess.
, vol.4
, pp. 75-115
-
-
Barton, H.A.1
Andersen, M.E.2
Clewell, H.J.3
-
7
-
-
0029100441
-
Incorporating biological information in quantitative risk assessment: An example with methylene chloride
-
Clewell, H. J. (1995). Incorporating biological information in quantitative risk assessment: An example with methylene chloride. Toxicology 102, 83-94.
-
(1995)
Toxicology
, vol.102
, pp. 83-94
-
-
Clewell, H.J.1
-
8
-
-
0024951584
-
Choice of dose measure for extrapolating carcinogenic risk from animals to humans: An empirical investigation of 23 chemicals
-
Crump, K., Allen, B., and Shipp, A. (1989). Choice of dose measure for extrapolating carcinogenic risk from animals to humans: An empirical investigation of 23 chemicals. Health Phys. 57, 387-393.
-
(1989)
Health Phys.
, vol.57
, pp. 387-393
-
-
Crump, K.1
Allen, B.2
Shipp, A.3
-
10
-
-
0001853113
-
Methods for establishing oral reference doses (RfDs)
-
W. Mertz, C. O. Abernathy, and S. S. Olin, Eds., ILSI Press, Washington, DC
-
Dourson, M. L. (1994). Methods for establishing oral reference doses (RfDs). In Risk Assessment of Essential Elements. (W. Mertz, C. O. Abernathy, and S. S. Olin, Eds.), pp. 51-61. ILSI Press, Washington, DC.
-
(1994)
Risk Assessment of Essential Elements
, pp. 51-61
-
-
Dourson, M.L.1
-
11
-
-
0029803289
-
Evolution of science-based uncertainty factors in noncancer risk assessment
-
Dourson, M. L., Felter, S. P., and Robinson, D. (1996). Evolution of science-based uncertainty factors in noncancer risk assessment. Regul. Toxicol. Pharmacol. 24, 108-120.
-
(1996)
Regul. Toxicol. Pharmacol.
, vol.24
, pp. 108-120
-
-
Dourson, M.L.1
Felter, S.P.2
Robinson, D.3
-
12
-
-
0032447730
-
Boron tolerable intake: Re-evaluation of toxicokinetics for data-derived uncertainty factors
-
Dourson, M. L., Meier, A., Meek, B., Renwick, A., Ohanian, E., and Poirier, K. (1998). Boron tolerable intake: Re-evaluation of toxicokinetics for data-derived uncertainty factors. Biol. Trace Elem. Res. 66(1-3), 453-463.
-
(1998)
Biol. Trace Elem. Res.
, vol.66
, Issue.1-3
, pp. 453-463
-
-
Dourson, M.L.1
Meier, A.2
Meek, B.3
Renwick, A.4
Ohanian, E.5
Poirier, K.6
-
17
-
-
0003651643
-
-
See listing for individual chemicals and the glossary for risk assessment terms
-
EPA (Environmental Protection Agency) (2000b). Integrated Risk Information System (IRIS). National Center for Environmental Assessment. See listing for individual chemicals and the glossary for risk assessment terms. Available online at http://wwrw.epa.gov/iris.
-
(2000)
Integrated Risk Information System (IRIS). National Center for Environmental Assessment
-
-
-
18
-
-
22044438042
-
The inexact science of risk assessment (and implications for risk management)
-
Felter, S. F., and Dourson, M. L. (1998). The inexact science of risk assessment (and implications for risk management). Human Ecol. Risk Assess 2, 245-251.
-
(1998)
Human Ecol. Risk Assess
, vol.2
, pp. 245-251
-
-
Felter, S.F.1
Dourson, M.L.2
-
19
-
-
0031737679
-
Application of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry extrapolation of acidic vapors in the upper airways
-
Frederick, C., Bush, M. L., Subramaniam, R. P., Black, K. A., Finch, L., Kimbell, J. S., Morgan, K. T., Morris, J. B., and Ultman, J. S. (1998). Application of a hybrid computational fluid dynamics and physiologically based inhalation model for interspecies dosimetry extrapolation of acidic vapors in the upper airways. Toxicol. Appl. Pharmacol. 152, 211-231.
-
(1998)
Toxicol. Appl. Pharmacol.
, vol.152
, pp. 211-231
-
-
Frederick, C.1
Bush, M.L.2
Subramaniam, R.P.3
Black, K.A.4
Finch, L.5
Kimbell, J.S.6
Morgan, K.T.7
Morris, J.B.8
Ultman, J.S.9
-
21
-
-
0025604621
-
A physiologically based model for in vivo inhibition of acetylcholinesterase by diisopropyl fluorophosphate
-
Gearhart, J. M., Jepson, G. W., Clewell, H. J., III, Andersen, M. E., and Conolly, R. B. (1990). A physiologically based model for in vivo inhibition of acetylcholinesterase by diisopropyl fluorophosphate. Toxicol. Appl. Pharmacol. 106, 295-310.
-
(1990)
Toxicol. Appl. Pharmacol.
, vol.106
, pp. 295-310
-
-
Gearhart, J.M.1
Jepson, G.W.2
Clewell, H.J.3
Andersen, M.E.4
Conolly, R.B.5
-
22
-
-
0020963903
-
Physiologically based pharmacokinetic modeling: Principles and applications
-
Gerlowski, L. E., and Jain, R. K. (1983). Physiologically based pharmacokinetic modeling: Principles and applications. J. Pharm. Sci. 72, 103-1127.
-
(1983)
J. Pharm. Sci.
, vol.72
, pp. 103-1127
-
-
Gerlowski, L.E.1
Jain, R.K.2
-
23
-
-
0030891645
-
The relative susceptibility of animals and humans to the carcinogenic hazard posed by exposure to 2,3,7,8-TCDD: An analysis using standard and internal measures of dose
-
Hays, S., Aylward, L., Karch, N., and Paustenbach, D. (1997). The relative susceptibility of animals and humans to the carcinogenic hazard posed by exposure to 2,3,7,8-TCDD: An analysis using standard and internal measures of dose. Chemosphere 34(5-7), 1507-1522.
-
(1997)
Chemosphere
, vol.34
, Issue.5-7
, pp. 1507-1522
-
-
Hays, S.1
Aylward, L.2
Karch, N.3
Paustenbach, D.4
-
25
-
-
0343611605
-
Derivation of guidance values for health-based exposure limits
-
World Health Organization, Geneva
-
IPCS (International Programme on Chemical Safety) (1994). Derivation of guidance values for health-based exposure limits. Environmental Health Criteria No. 170: Assessing Human Health Risks of Chemicals. World Health Organization, Geneva.
-
(1994)
Environmental Health Criteria No. 170: Assessing Human Health Risks of Chemicals
-
-
-
26
-
-
0000406564
-
Inhalation RfC methodology: Dosimetric adjustments and dose-response estimation of noncancer toxicity in the upper respiratory tract
-
Jarabek, A. M. (1994). Inhalation RfC methodology: Dosimetric adjustments and dose-response estimation of noncancer toxicity in the upper respiratory tract. Inhal. Toxicol. 6(Suppl.), 301-325.
-
(1994)
Inhal. Toxicol.
, vol.6
, pp. 301-325
-
-
Jarabek, A.M.1
-
27
-
-
0029085471
-
The application of dosimetry models to identify key processes and parameters for default dose-response assessment approaches
-
Jarabek, A. M. (1995). The application of dosimetry models to identify key processes and parameters for default dose-response assessment approaches. Toxicol. Lett. 79, 171-184.
-
(1995)
Toxicol. Lett.
, vol.79
, pp. 171-184
-
-
Jarabek, A.M.1
-
29
-
-
0343176115
-
In vitro Human tissue models in risk assessment: Report of a consensus-building workshop in vitro human tissue models in risk assessment
-
in press
-
MacGregor, J. T., Collins, J. M., Sugiyama, Y., Tyson, C. A., Dean, J., Smith, L., Andersen, M., Curren, R., Houston, J. B., Kadlubar, F. K., Kedderis, G. L., Krishnan, K., Li, A., Parchment, R. E., Thummel, K., Tomaszewski, J. E., Ulrich, R., Vickers, A. E. M., and Wrighton, S. A. (2000). In vitro Human tissue models in risk assessment: Report of a consensus-building workshop In vitro human tissue models in risk assessment. Toxicol. Sci., in press.
-
(2000)
Toxicol. Sci.
-
-
MacGregor, J.T.1
Collins, J.M.2
Sugiyama, Y.3
Tyson, C.A.4
Dean, J.5
Smith, L.6
Andersen, M.7
Curren, R.8
Houston, J.B.9
Kadlubar, F.K.10
Kedderis, G.L.11
Krishnan, K.12
Li, A.13
Parchment, R.E.14
Thummel, K.15
Tomaszewski, J.E.16
Ulrich, R.17
Vickers, A.E.M.18
Wrighton, S.A.19
-
30
-
-
0028077675
-
Approach to assessment of risk to human health for priority substances under the Canadian Environmental Protection Act
-
Meek, M. E., Newhook, R., Liteplo, R. G., and V. C. Armstrong. (1994). Approach to assessment of risk to human health for priority substances under the Canadian Environmental Protection Act. Environ. Carcinogen. Ecotoxicol. Rev. C12(2), 105-134.
-
(1994)
Environ. Carcinogen. Ecotoxicol. Rev.
, vol.C12
, Issue.2
, pp. 105-134
-
-
Meek, M.E.1
Newhook, R.2
Liteplo, R.G.3
Armstrong, V.C.4
-
31
-
-
0343611604
-
-
In press
-
Meek, B., Renwick, A., Ohanian, E., Dourson, M., Lake, B., Naumann, B., and Vu, V. (2001). Guidelines for application of compound specific adjustment factors (CSAF) in dose/concentration response assessment. In press.
-
(2001)
Guidelines for Application of Compound Specific Adjustment Factors (CSAF) in Dose/concentration Response Assessment
-
-
Meek, B.1
Renwick, A.2
Ohanian, E.3
Dourson, M.4
Lake, B.5
Naumann, B.6
Vu, V.7
-
32
-
-
85213594623
-
Data-derived uncertainty factors: Boric acid (BA) as a case study
-
in press
-
Murray, F. J., and Andersen, M. E. (2000). Data-derived uncertainty factors: Boric acid (BA) as a case study. Hum. Ecol. Risk Assess., in press.
-
(2000)
Hum. Ecol. Risk Assess.
-
-
Murray, F.J.1
Andersen, M.E.2
-
34
-
-
0004158548
-
-
National Academy Press, Washington, DC
-
NAS (National Academy of Sciences) (1994). Science and Judgment in Risk Assessment, National Academy Press, Washington, DC.
-
(1994)
Science and Judgment in Risk Assessment
-
-
-
37
-
-
0002042336
-
Subchronic toxicity study of sodium arsenite in methyl-deficient male C57BL/6 mice
-
W. Chappell, C. Abernathy, and R. Calderon, Eds., Elsevier, Amsterdam, The Netherland
-
Okoji, R., Leininger, J., and Froines, J. (1999). Subchronic toxicity study of sodium arsenite in methyl-deficient male C57BL/6 mice. In: Arsenic Exposure and Health Effects (W. Chappell, C. Abernathy, and R. Calderon, Eds.), pp. 225-232. Elsevier, Amsterdam, The Netherland.
-
(1999)
Arsenic Exposure and Health Effects
, pp. 225-232
-
-
Okoji, R.1
Leininger, J.2
Froines, J.3
-
38
-
-
0033771951
-
Concordance of the toxicity of pharmaceuticals in humans and in animals
-
Olson, H., Betton, G., Robinson, D., et al. (2000). Concordance of the toxicity of pharmaceuticals in humans and in animals. Regul. Toxicol. Pharmacol. 32, 56-67.
-
(2000)
Regul. Toxicol. Pharmacol.
, vol.32
, pp. 56-67
-
-
Olson, H.1
Betton, G.2
Robinson, D.3
-
39
-
-
0031062288
-
Physiologically-based modeling of vinyl acetate uptake, metabolism and intracellular pH changes in the rat nasal cavity
-
Plowchalk, D. R., Andersen, M. E., and Bogdanffy, M. S. (1997). Physiologically-based modeling of vinyl acetate uptake, metabolism and intracellular pH changes in the rat nasal cavity. Toxicol. Appl. Pharmacol. 142, 386-400.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.142
, pp. 386-400
-
-
Plowchalk, D.R.1
Andersen, M.E.2
Bogdanffy, M.S.3
-
40
-
-
0024515167
-
In vitro metabolism of methylene chloride in human and animal tissues: Use in physiologically based pharmacokinetic models
-
Reitz, R. H., Mendrela, A. L., and Guengerich, F. P. (1989). In vitro metabolism of methylene chloride in human and animal tissues: Use in physiologically based pharmacokinetic models. Toxicol. Appl. Pharmacol. 97, 230-246.
-
(1989)
Toxicol. Appl. Pharmacol.
, vol.97
, pp. 230-246
-
-
Reitz, R.H.1
Mendrela, A.L.2
Guengerich, F.P.3
-
41
-
-
0027171701
-
Data derived safety factors for the evaluation of food additives and environmental contaminants
-
Renwick, A. G. (1993). Data derived safety factors for the evaluation of food additives and environmental contaminants. Food Addit. Contam. 10(3), 275-305.
-
(1993)
Food Addit. Contam.
, vol.10
, Issue.3
, pp. 275-305
-
-
Renwick, A.G.1
-
42
-
-
0031809917
-
Human variability and noncancer risk assessment-An analysis of the default uncertainty factor
-
Renwick, A., and Lazarus, N. R. (1998). Human variability and noncancer risk assessment-An analysis of the default uncertainty factor. Regul. Toxicol. Pharmacol. 27, 3-20.
-
(1998)
Regul. Toxicol. Pharmacol.
, vol.27
, pp. 3-20
-
-
Renwick, A.1
Lazarus, N.R.2
-
43
-
-
0342306569
-
Monitoring human subjects and clinical trials
-
Russo, E. (2000). Monitoring human subjects and clinical trials. Scientist May 15, p. 6.
-
(2000)
Scientist May
, vol.15
, pp. 6
-
-
Russo, E.1
-
46
-
-
0030069951
-
Variability in biological exposure indices using physiologically based pharmacokinetic modeling and Monte Carlo simulation
-
Thomas, R. S., Bigelow, P. L., Keefe, T. J., and Yang, R. S. H. (1996). Variability in biological exposure indices using physiologically based pharmacokinetic modeling and Monte Carlo simulation. Amer. Ind. Hyg. Assoc. J. 57, 23-32.
-
(1996)
Amer. Ind. Hyg. Assoc. J.
, vol.57
, pp. 23-32
-
-
Thomas, R.S.1
Bigelow, P.L.2
Keefe, T.J.3
Yang, R.S.H.4
|