Zymosan modulates CD44 isoform expression in a murine model of inflammation resembling rheumatoid arthritis synovitis

Journal of Rheumatology

Volumn 28, Issue 5, 2001, Pages 943-949

  Cabrera, P V ^a   Blanco, G ^a   Gravisaco, M J ^a   Alvarez, E ^a   Hajos, S ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Air pouch; Arthritis like inflammation; CD44 isoforms; Zymosan

Indexed keywords

HERMES ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; LEUKOCYTE COUNT; LEUKOCYTE MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD44; ARTHRITIS, RHEUMATOID; BLOTTING, SOUTHERN; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; EXONS; EXUDATES AND TRANSUDATES; FLOW CYTOMETRY; GENE EXPRESSION; ISOMERISM; LEUKOCYTES; MICE; RNA, MESSENGER; SYNOVITIS; TUMOR NECROSIS FACTOR-ALPHA; ZYMOSAN;

EID: 0035023034     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. The formation of a structure with the features of synovial lining by subcutaneous injection of air: In vivo tissue culture system
2. Characterization of zymosan-induced arthritis in the rat: Effects on joint inflammation and cartilage metabolism
3. The effect of leukotriene synthesis inhibitors in models of acute and chronic inflammation
4. Periarthritis promotes gait disturbance in zymosan-induced arthritis in rats
5. Modulation of IL-1 induced neutrophil migration by dexamethasone and lipocortin 1
6. 2 activity in the zymosan rat air pouch model of inflammation
7. 2 production but not antigen presenting functions
8. Stimulation of human monocyte beta-glucan receptors by glucan particles induces production of TNF-alpha and IL-1 beta
9. (1-3)-β-D-glucan stimulates nitric oxide generation and cytokine mRNA expression in macrophages
10. CD44 is the principal cell surface receptor for hyaluronate
11. Hyaluronate can function as cell adhesion molecule and CD44 participates in hyaluronate recognition
12. LFA-3, CD44 and CD45: Physiologic triggers of human monocyte TNF and IL-1 release
13. CD44 and its interactions with extracellular matrix
14. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
15. Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain
16. Identification of hyaluronic acid binding sites in the extracellular domain of CD44
17. Antibodies against the CD44 p80 lymphocyte homing receptor molecule augment human peripheral blood T-cell activation
18. CD44: A molecule involved in leukocyte adherence and T-cell activation
19. CD44 contributes to T cell activation
20. A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family
21. Activation of CD44 and hyaluronan in immunological systems
22. Expression of the Hermes-1 (CD44) and ICAM-1 (CD54) molecule on the surface of thyroid cells from patients with Graves' disease
23. Adhesion molecule expression on cerebrospinal fluid T lymphocytes: Evidence of common recruitment mechanisms in multiple sclerosis, aseptic meningitis and normal controls
24. Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Upregulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis
25. Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis
26. Administration of antibodies to hyaluronan receptor (CD44) delays the start and ameliorates the severity of collagen II arthritis
27. CD44 expression by leukocytes in rheumatoid arthritis and modulation by specific antibody: Implications for lymphocyte adhesion to endothelial cells and synoviocytes in vitro
28. Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA dependent primary adhesion
29. Hyaluronate activation of CD44 induces insulin-like growth factor-1 expression by a tumor necrosis factor-alpha-dependent mechanism in murine macrophages
30. Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages
31. Upregulation of CD44 in the inflamed mouse air pouch injected with synthetic lipid A
32. Nitric-oxide synthase and cyclo-oxygenase pathways in the inflammatory response, induced by zymosan in the rat air pouch
33. Alternative exon-specific PCR method for the analysis of human CD44 isoform expression
34. Cytokine induction of the ability of human monocyte CD44 to bind hyaluronan is mediated primarily by TNF-α and is inhibited by IL-4 and IL-13
35. Expression of CD44 variants in human inflammatory synovitis
36. In vitro culture of human peripheral blood monocytes induces hyaluronan binding and upregulates monocyte variant CD44 isoform expression
37. Activation dependent modulation of hyaluronate-receptor and of hyaluronate avidity by human monocytes