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Volumn 16, Issue 5, 2001, Pages 988-996

Altered prostate growth and daily sperm production in male mice exposed prenatally to subclinical doses of 17α-ethinyl oestradiol

Author keywords

Endocrine disruption; Fetus; Oral contraceptive; Prostate; Testes

Indexed keywords

17ALPHA ESTRADIOL; ANDROGEN RECEPTOR; ORAL CONTRACEPTIVE AGENT;

EID: 0035021958     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/16.5.988     Document Type: Article
Times cited : (123)

References (62)
  • 1
    • 0027281816 scopus 로고
    • Contraceptives and congenital anomalies. ACOG committee opinion: Committee on gynecologic practice. Number 124-July 1993
    • American College of Obstetrics and Gynecology (1993) Contraceptives and congenital anomalies. ACOG committee opinion: Committee on gynecologic practice. Number 124-July 1993. Int. J. Gynaecol. Obstet., 42, 316-317.
    • (1993) Int. J. Gynaecol. Obstet. , vol.42 , pp. 316-317
  • 2
    • 0019176336 scopus 로고
    • Assay of ethinyl oestradiol in human serum and its binding to plasma proteins
    • Akpoviroro, J. and Fotherby, K. (1980) Assay of ethinyl oestradiol in human serum and its binding to plasma proteins. J. Steroid Biochem., 13, 773-779.
    • (1980) J. Steroid Biochem. , vol.13 , pp. 773-779
    • Akpoviroro, J.1    Fotherby, K.2
  • 3
    • 0004523610 scopus 로고    scopus 로고
    • Uterine response to estradiol: Low-dose facilitation and high-dose inhibition due to fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice
    • Tulane University, New Orleans, LA
    • Alworth, L., Howdeshell, K., Ruhlen, R. et al. (1999) Uterine response to estradiol: low-dose facilitation and high-dose inhibition due to fetal exposure to diethylstilbestrol and methoxychlor in CD-1 mice. Paper presented at the Environmental Hormones meeting. Tulane University, New Orleans, LA.
    • (1999) Environmental Hormones Meeting
    • Alworth, L.1    Howdeshell, K.2    Ruhlen, R.3
  • 4
    • 0023241015 scopus 로고
    • Long-term alterations in histology and steroid receptor levels of the genital tract and mammary gland following neonatal exposure of female balb/ccrgl mice to various doses of diethylstilbestrol
    • Bern, H.A., Edery, M., Mills, K.T. et al. (1987) Long-term alterations in histology and steroid receptor levels of the genital tract and mammary gland following neonatal exposure of female balb/ccrgl mice to various doses of diethylstilbestrol. Cancer Res., 47, 4165-4172.
    • (1987) Cancer Res. , vol.47 , pp. 4165-4172
    • Bern, H.A.1    Edery, M.2    Mills, K.T.3
  • 5
    • 0025146990 scopus 로고
    • Changing relationships between testis size, Sertoli cell number and spermatogenesis in Sprague-Dawley rats
    • Berndtson, W.E. and Thompson, T.L. (1990) Changing relationships between testis size, Sertoli cell number and spermatogenesis in Sprague-Dawley rats. J Androl., 11, 429-435.
    • (1990) J Androl. , vol.11 , pp. 429-435
    • Berndtson, W.E.1    Thompson, T.L.2
  • 6
    • 0017341010 scopus 로고
    • Follow-up study of male and female offspring of DES-exposed mothers
    • Bibbo, M., Gill, W.B., Azizi, F. et al. (1977) Follow-up study of male and female offspring of DES-exposed mothers. Obstet. Gynecol., 49, 1-8.
    • (1977) Obstet. Gynecol. , vol.49 , pp. 1-8
    • Bibbo, M.1    Gill, W.B.2    Azizi, F.3
  • 7
    • 0027012870 scopus 로고
    • Disease patterns and antibody responses to viral antigens in women exposed in utero to diethylstilbestrol
    • Colborn, T. and Clement, C. (eds), Princeton Scientific Publishing Company, Inc., Princeton
    • Blair, P.B., Noller, K.L., Turiel, J. et al. (1992) Disease patterns and antibody responses to viral antigens in women exposed in utero to diethylstilbestrol. In Colborn, T. and Clement, C. (eds), Chemically-Induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection. Princeton Scientific Publishing Company, Inc., Princeton, pp. 283-288.
    • (1992) Chemically-induced Alterations in Sexual and Functional Development: The Wildlife/human Connection , pp. 283-288
    • Blair, P.B.1    Noller, K.L.2    Turiel, J.3
  • 8
    • 0023686424 scopus 로고
    • Uterine abnormalities in rats exposed neonatally to diethylstilbestrol, ethynylestradiol, or clomiphene citrate
    • Branham, W.S., Zehr, D.R., Chen, J.J. et al. (1988) Uterine abnormalities in rats exposed neonatally to diethylstilbestrol, ethynylestradiol, or clomiphene citrate. Toxicology, 51, 201-212.
    • (1988) Toxicology , vol.51 , pp. 201-212
    • Branham, W.S.1    Zehr, D.R.2    Chen, J.J.3
  • 9
    • 0024411870 scopus 로고
    • Protein measurement using bicinchoninic acid: Elimination of interfering substances
    • Brown, R.E., Jarvis, K.L. and Hyland, K.J. (1989) Protein measurement using bicinchoninic acid: elimination of interfering substances. Anal. Biochem., 180, 136-139.
    • (1989) Anal. Biochem. , vol.180 , pp. 136-139
    • Brown, R.E.1    Jarvis, K.L.2    Hyland, K.J.3
  • 11
    • 0025916432 scopus 로고
    • Increased sperm production in adult rats after transient neonatal hypothyroidism
    • Cooke, P.S., Hess, R.A., Porcelli, J. et al. (1991) Increased sperm production in adult rats after transient neonatal hypothyroidism. Endocrinology, 129, 244-248.
    • (1991) Endocrinology , vol.129 , pp. 244-248
    • Cooke, P.S.1    Hess, R.A.2    Porcelli, J.3
  • 12
    • 0002140672 scopus 로고    scopus 로고
    • Comparative embryology
    • Hood, R.D. (ed.), CRC Press, New York
    • DeSesso, J.M. (1997) Comparative embryology. In Hood, R.D. (ed.), Handbook of Developmental Toxicology. CRC Press, New York, pp. 111-174.
    • (1997) Handbook of Developmental Toxicology , pp. 111-174
    • Desesso, J.M.1
  • 13
    • 0000527132 scopus 로고
    • Cysts of the epididymis, cancer of the cervix, granular cell myoblastoma, and other lesions after estrogen injection in newborn mice
    • Dunn, T. and Green, A. (1963) Cysts of the epididymis, cancer of the cervix, granular cell myoblastoma, and other lesions after estrogen injection in newborn mice. J. Natl Cancer Inst., 31, 425-438.
    • (1963) J. Natl Cancer Inst. , vol.31 , pp. 425-438
    • Dunn, T.1    Green, A.2
  • 14
    • 0017126528 scopus 로고
    • Structural and functional abnormalities in the sex organs of male offspring of mothers treated with diethylstilbestrol (DES)
    • Gill, W.B., Schumacher, G.F. and Bibbo, M. (1976) Structural and functional abnormalities in the sex organs of male offspring of mothers treated with diethylstilbestrol (DES). J. Reprod. Med., 16, 147-153.
    • (1976) J. Reprod. Med. , vol.16 , pp. 147-153
    • Gill, W.B.1    Schumacher, G.F.2    Bibbo, M.3
  • 15
    • 0029053049 scopus 로고
    • Diethylstilbestrol revisited: A review of the long-term health effects
    • Giusti, R.M., Iwamoto, K. and Hatch, E.E. (1995) Diethylstilbestrol revisited: a review of the long-term health effects. Ann. Intern. Med., 122, 778-788.
    • (1995) Ann. Intern. Med. , vol.122 , pp. 778-788
    • Giusti, R.M.1    Iwamoto, K.2    Hatch, E.E.3
  • 16
    • 0027013380 scopus 로고
    • Chemical-induced alterations of sexual differentiation: A review of effects in humans and rodents
    • Colborn, T. and Clement, C. (eds), Princeton Scientific Publishing Company, Inc., Princeton
    • Gray, L.E. (1992) Chemical-induced alterations of sexual differentiation: A review of effects in humans and rodents. In Colborn, T. and Clement, C. (eds), Chemically-Induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection. Princeton Scientific Publishing Company, Inc., Princeton, pp. 203-230.
    • (1992) Chemically-induced Alterations in Sexual and Functional Development: The Wildlife/human Connection , pp. 203-230
    • Gray, L.E.1
  • 17
    • 0034106556 scopus 로고    scopus 로고
    • Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals
    • Gupta, C. (2000) Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals. Proc. Soc. Exp. Biol. Med., 224, 61-68.
    • (2000) Proc. Soc. Exp. Biol. Med. , vol.224 , pp. 61-68
    • Gupta, C.1
  • 18
    • 0025906320 scopus 로고
    • Fertility study of oral contraceptives dt-5061 and dt-5062 (1/35) in rats
    • Harada, S., Takayama, S., Shibano, T. et al. (1991a) Fertility study of oral contraceptives dt-5061 and dt-5062 (1/35) in rats. Yakuri To Chiryo, 19, 157-196.
    • (1991) Yakuri To Chiryo , vol.19 , pp. 157-196
    • Harada, S.1    Takayama, S.2    Shibano, T.3
  • 19
    • 0025906322 scopus 로고
    • Teratogenicity study of oral contraceptives dt-5061 and dt-5062 (1/35) in rats
    • Harada, S., Takayama, S., Shibano, T. et al. (1991b) Teratogenicity study of oral contraceptives dt-5061 and dt-5062 (1/35) in rats. Yakuri To Chiryo, 19, 197-231.
    • (1991) Yakuri To Chiryo , vol.19 , pp. 197-231
    • Harada, S.1    Takayama, S.2    Shibano, T.3
  • 20
    • 0019843040 scopus 로고
    • Diethylstilbestrol and other sex hormones during pregnancy
    • Herbst, A.L. (1981) Diethylstilbestrol and other sex hormones during pregnancy. Obstet. Gynecol., 58, 35S-40S.
    • (1981) Obstet. Gynecol. , vol.58
    • Herbst, A.L.1
  • 21
    • 0018751070 scopus 로고
    • Prenatal diethylstilbestrol exposure and human genital tract abnormalities
    • Herbst, A.L., Scully, R.E. and Robboy, S.J. (1979) Prenatal diethylstilbestrol exposure and human genital tract abnormalities. Natl Cancer Inst. Monogr., 25-35.
    • (1979) Natl Cancer Inst. Monogr. , pp. 25-35
    • Herbst, A.L.1    Scully, R.E.2    Robboy, S.J.3
  • 22
    • 0027021743 scopus 로고
    • Surrounded by estrogens? Considerations for neurobehavioral development in human beings
    • Colborn, T. and Clement, C. (eds). Princeton Scientific Publishing Company, Inc., Princeton
    • Hines, M. (1992) Surrounded by estrogens? Considerations for neurobehavioral development in human beings. In Colborn, T. and Clement, C. (eds). Chemically-Induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection. Princeton Scientific Publishing Company, Inc., Princeton, pp. 261-282.
    • (1992) Chemically-induced Alterations in Sexual and Functional Development: The Wildlife/human Connection , pp. 261-282
    • Hines, M.1
  • 23
    • 0033063642 scopus 로고    scopus 로고
    • Large observational trial of a new low-dose oral contraceptive containing 20 micrograms ethinylestradiol and 100 micrograms levonorgestrel (Miranova) in Germany
    • Hite, R.C., Bannemerschult, R., Fox-Kuchenbecker, P. et al. (1999) Large observational trial of a new low-dose oral contraceptive containing 20 micrograms ethinylestradiol and 100 micrograms levonorgestrel (Miranova) in Germany. Eur. J. Contracept. Reprod. Health Care, 4, 7-13.
    • (1999) Eur. J. Contracept. Reprod. Health Care , vol.4 , pp. 7-13
    • Hite, R.C.1    Bannemerschult, R.2    Fox-Kuchenbecker, P.3
  • 24
    • 0027140989 scopus 로고
    • Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse
    • Joyce, K.L., Porcelli, J. and Cooke, P.S. (1993) Neonatal goitrogen treatment increases adult testis size and sperm production in the mouse. J. Androl., 14, 448-455.
    • (1993) J. Androl. , vol.14 , pp. 448-455
    • Joyce, K.L.1    Porcelli, J.2    Cooke, P.S.3
  • 25
    • 0025986733 scopus 로고
    • Oral contraceptives in the etiology of isolated hypospadias
    • Kallen, B., Mastroiacovo, P., Lancaster, P.A. et al (1991) Oral contraceptives in the etiology of isolated hypospadias. Contraception, 44, 173-182.
    • (1991) Contraception , vol.44 , pp. 173-182
    • Kallen, B.1    Mastroiacovo, P.2    Lancaster, P.A.3
  • 26
    • 0030499023 scopus 로고    scopus 로고
    • A perspective on the risk assessment process for endocrine-disruptive effects on wildlife and human health
    • Kavlock, R.J. and Ankley, G.T. (1996) A perspective on the risk assessment process for endocrine-disruptive effects on wildlife and human health. Risk Anal, 16, 731-739.
    • (1996) Risk Anal , vol.16 , pp. 731-739
    • Kavlock, R.J.1    Ankley, G.T.2
  • 27
    • 0021345054 scopus 로고
    • Proliferation of spermatogonia and sertoli cells in maturing mice
    • Kluin, P.M., Kramer, M.F. and de Rooij, D.G. (1984) Proliferation of spermatogonia and Sertoli cells in maturing mice. Anat. Embryol., 169, 73-78.
    • (1984) Anat. Embryol. , vol.169 , pp. 73-78
    • Kluin, P.M.1    Kramer, M.F.2    De Rooij, D.G.3
  • 28
    • 0018850985 scopus 로고
    • A simple, rapid, and sensitive DNA assay procedure
    • Labarca, C. and Paigen, K. (1980) A simple, rapid, and sensitive DNA assay procedure. Anal. Biochem., 102, 344-352.
    • (1980) Anal. Biochem. , vol.102 , pp. 344-352
    • Labarca, C.1    Paigen, K.2
  • 29
    • 0031670824 scopus 로고    scopus 로고
    • Reply to 'prenatal exposure to sex hormones: A case-control study' (letter)
    • Li, D.K. (1998) Reply to 'Prenatal exposure to sex hormones: a case-control study' (letter). Teratology, 58, 1.
    • (1998) Teratology , vol.58 , pp. 1
    • Li, D.K.1
  • 30
    • 0028940832 scopus 로고
    • Oral contraceptive use after conception in relation to the risk of congenital urinary tract anomalies
    • Li, D.K., Daling, J.R., Mueller, B.A. et al. (1995) Oral contraceptive use after conception in relation to the risk of congenital urinary tract anomalies. Teratology, 51, 30-36.
    • (1995) Teratology , vol.51 , pp. 30-36
    • Li, D.K.1    Daling, J.R.2    Mueller, B.A.3
  • 32
    • 0019920201 scopus 로고
    • Reduced fertility in female mice exposed transplacentally to diethylstilbestrol (des)
    • McLachlan, J.A., Newbold, R.R., Shah, H.C. et al. (1982) Reduced fertility in female mice exposed transplacentally to diethylstilbestrol (DES). Fertil. Steril., 38, 364-371.
    • (1982) Fertil. Steril. , vol.38 , pp. 364-371
    • McLachlan, J.A.1    Newbold, R.R.2    Shah, H.C.3
  • 33
    • 0029095197 scopus 로고
    • Teratogen update: Carcinogenesis and teratogenesis associated with exposure to diethylstilbestrol (DES) in utero
    • Mittendorf, R. (1995) Teratogen update: carcinogenesis and teratogenesis associated with exposure to diethylstilbestrol (DES) in utero. Teratology, 51, 435-445.
    • (1995) Teratology , vol.51 , pp. 435-445
    • Mittendorf, R.1
  • 34
    • 0031935548 scopus 로고    scopus 로고
    • The effective free fraction of estradiol and xenoestrogens in human serum measured by whole cell uptake assays: Physiology of delivery modifies estrogenic activity
    • Nagel, S.C., vom Saal, F.S. and Welshons, W.V. (1998) The effective free fraction of estradiol and xenoestrogens in human serum measured by whole cell uptake assays: physiology of delivery modifies estrogenic activity. Proc. Soc. Exp. Biol. Med., 217, 300-309.
    • (1998) Proc. Soc. Exp. Biol. Med. , vol.217 , pp. 300-309
    • Nagel, S.C.1    Vom Saal, F.S.2    Welshons, W.V.3
  • 35
    • 0003637272 scopus 로고    scopus 로고
    • National Academy Press, Washington, DC
    • National Research Council (1999) Hormonally active agents in the environment. National Academy Press, Washington, DC.
    • (1999) Hormonally Active Agents in the Environment
  • 36
    • 0028822138 scopus 로고
    • Cellular and molecular effects of developmental exposure to diethylstilbestrol: Implications for other environmental estrogens
    • Newbold, R. (1995) Cellular and molecular effects of developmental exposure to diethylstilbestrol: implications for other environmental estrogens. Environ. Health Perspect., 103, 83-87.
    • (1995) Environ. Health Perspect. , vol.103 , pp. 83-87
    • Newbold, R.1
  • 38
    • 0026739325 scopus 로고
    • Intrauterine position effects on steroid metabolism and steroid receptors of reproductive organs in male mice
    • Nonneman, D.J., Ganjam, V.K., Welshons, W.V. et al. (1992) Intrauterine position effects on steroid metabolism and steroid receptors of reproductive organs in male mice. Biol. Reprod., 47, 723-729.
    • (1992) Biol. Reprod. , vol.47 , pp. 723-729
    • Nonneman, D.J.1    Ganjam, V.K.2    Welshons, W.V.3
  • 39
    • 0032945377 scopus 로고    scopus 로고
    • International trends in rates of hypospadias and cryptorchidism
    • Paulozzi, L.J. (1999) International trends in rates of hypospadias and cryptorchidism. Environ. Health Perspect., 107, 297-302.
    • (1999) Environ. Health Perspect. , vol.107 , pp. 297-302
    • Paulozzi, L.J.1
  • 41
    • 26844495001 scopus 로고    scopus 로고
    • Survey and assessment of mammalian estrogen biological assays for hazard characterization
    • Reel, J.R., Lamb, I.J. and Neal, B.H. (1996) Survey and assessment of mammalian estrogen biological assays for hazard characterization. Fundam. Appl. Toxicol., 34, 288-305.
    • (1996) Fundam. Appl. Toxicol. , vol.34 , pp. 288-305
    • Reel, J.R.1    Lamb, I.J.2    Neal, B.H.3
  • 42
    • 0018088898 scopus 로고
    • Daily sperm production and epididymal sperm reserves of pubertal and adult rats
    • Robb, G.W., Amann, R.P. and Killian, G.J. (1978) Daily sperm production and epididymal sperm reserves of pubertal and adult rats. J. Reprod. Fertil., 54, 103-107.
    • (1978) J. Reprod. Fertil. , vol.54 , pp. 103-107
    • Robb, G.W.1    Amann, R.P.2    Killian, G.J.3
  • 43
    • 0017064982 scopus 로고
    • The fate of diethylstilbestrol in the pregnant mouse
    • Shah, H.C. and McLachlan, J.A. (1976) The fate of diethylstilbestrol in the pregnant mouse. J Pharmacol. Exp. Ther., 197, 687-696.
    • (1976) J Pharmacol. Exp. Ther. , vol.197 , pp. 687-696
    • Shah, H.C.1    McLachlan, J.A.2
  • 44
    • 0027232797 scopus 로고
    • Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract?
    • Sharpe, R.M. and Skakkebaek, N.E. (1993) Are oestrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet, 341, 1392-1395.
    • (1993) Lancet , vol.341 , pp. 1392-1395
    • Sharpe, R.M.1    Skakkebaek, N.E.2
  • 45
    • 0019916124 scopus 로고
    • Placental transfer and metabolism of 17 alpha-ethynylestradiol-17 beta and estradiol-17 beta in the rhesus monkey
    • Slikker, W., Jr., Bailey, J.R., Newport, D. et al. (1982) Placental transfer and metabolism of 17 alpha-ethynylestradiol-17 beta and estradiol-17 beta in the rhesus monkey. J. Pharmacol. Exp. Ther., 223, 483-489.
    • (1982) J. Pharmacol. Exp. Ther. , vol.223 , pp. 483-489
    • Slikker W., Jr.1    Bailey, J.R.2    Newport, D.3
  • 46
    • 0019519155 scopus 로고
    • Oral contraceptives and birth defects
    • Smithells, R.W. (1981) Oral contraceptives and birth defects. Dev. Med. Child Neurol., 23, 369-372.
    • (1981) Dev. Med. Child Neurol. , vol.23 , pp. 369-372
    • Smithells, R.W.1
  • 47
    • 0020055365 scopus 로고
    • In utero exposure to diethylstilbestrol: Adverse effects on the reproductive tract and reproductive performance and male and female offspring
    • Stillman, R.J. (1982) In utero exposure to diethylstilbestrol: adverse effects on the reproductive tract and reproductive performance and male and female offspring. Am. J. Obstel. Gynecol., 142, 905-921.
    • (1982) Am. J. Obstel. Gynecol. , vol.142 , pp. 905-921
    • Stillman, R.J.1
  • 48
    • 0031455688 scopus 로고    scopus 로고
    • Have sperm densities declined? A reanalysis of global trend data
    • Swan, S.H., Elkin, E.P. and Fenster, L. (1997) Have sperm densities declined? A reanalysis of global trend data. Environ. Health Perspect., 105, 1228-1232.
    • (1997) Environ. Health Perspect. , vol.105 , pp. 1228-1232
    • Swan, S.H.1    Elkin, E.P.2    Fenster, L.3
  • 49
    • 0003287788 scopus 로고    scopus 로고
    • Alterations in male reproductive development: The role of endocrine disrupting chemicals
    • Metzler, M. (ed.), Springer-Verlag, Heidelberg (in press)
    • Swan, S.H. and vom Saal, F.S. (2001) Alterations in male reproductive development: the role of endocrine disrupting chemicals. In Metzler, M. (ed.), Endocrine Disruptors in the Environment. Springer-Verlag, Heidelberg (in press).
    • (2001) Endocrine Disruptors in the Environment
    • Swan, S.H.1    Vom Saal, F.S.2
  • 50
    • 0000260769 scopus 로고
    • Tissue changes in mice with persistent vaginal cornification induced by early postnatal treatment with estrogen
    • Takasugi, N. and Bern, H. (1964) Tissue changes in mice with persistent vaginal cornification induced by early postnatal treatment with estrogen. J. Natl Cancer Inst., 33, 855-865.
    • (1964) J. Natl Cancer Inst. , vol.33 , pp. 855-865
    • Takasugi, N.1    Bern, H.2
  • 51
    • 0028906048 scopus 로고
    • Relationship of growth stimulated by lithium, estradiol and EGF to phospholipase C activity in MCF-7 human breast cancer cells
    • Taylor, J.A., Grady, L.H., Engler, K.S. and Welshons, W.V. (1995) Relationship of growth stimulated by lithium, estradiol and EGF to phospholipase C activity in MCF-7 human breast cancer cells. Breast Cancer Res. Treat., 34, 265-277.
    • (1995) Breast Cancer Res. Treat. , vol.34 , pp. 265-277
    • Taylor, J.A.1    Grady, L.H.2    Engler, K.S.W.3
  • 52
    • 1842309752 scopus 로고    scopus 로고
    • Male reproductive health and environmental xenoestrogens
    • Toppari, J., Larsen, J.C., Christiansen, P. et at. (1996) Male reproductive health and environmental xenoestrogens. Environ. Health Perspect., 104 (Suppl. 4), 741-803.
    • (1996) Environ. Health Perspect. , vol.104 , Issue.SUPPL. 4 , pp. 741-803
    • Toppari, J.1    Larsen, J.C.2    Christiansen, P.3
  • 53
    • 0025884678 scopus 로고
    • Proliferative activity of gonocytes, sertoli cells and interstitial cells during testicular development in mice
    • Vergouwen, R.P., Jacobs, S.G., Huiskamp, R. et al. (1991) Proliferative activity of gonocytes, Sertoli cells and interstitial cells during testicular development in mice. J. Reprod. Fertil., 93, 233-243.
    • (1991) J. Reprod. Fertil. , vol.93 , pp. 233-243
    • Vergouwen, R.P.1    Jacobs, S.G.2    Huiskamp, R.3
  • 54
    • 12644300617 scopus 로고    scopus 로고
    • Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses
    • vom Saal, F.S., Timms, B.G., Montano, M.M. et al. (1997) Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses. Proc. Natl Acad. Sci. USA, 94, 2056-2061.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 2056-2061
    • Vom Saal, F.S.1    Timms, B.G.2    Montano, M.M.3
  • 55
    • 0025066375 scopus 로고
    • The effect of in utero ethinyl oestradiol exposure on the risk of cryptorchid testis and testicular teratoma in mice
    • Walker, A.H., Bernstein, L., Warren, D.W. et al. (1990) The effect of in utero ethinyl oestradiol exposure on the risk of cryptorchid testis and testicular teratoma in mice. Br. J. Cancer, 62, 599-602.
    • (1990) Br. J. Cancer , vol.62 , pp. 599-602
    • Walker, A.H.1    Bernstein, L.2    Warren, D.W.3
  • 56
    • 0029072236 scopus 로고
    • Fertility in men exposed prenatally to diethylstilbestrol
    • Wilcox, A.J., Baird, D.D., Weinberg, C.R. et al. (1995) Fertility in men exposed prenatally to diethylstilbestrol. N. Engl. J. Med., 332, 1411-1416.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1411-1416
    • Wilcox, A.J.1    Baird, D.D.2    Weinberg, C.R.3
  • 57
    • 0021891678 scopus 로고
    • Effect of ethinyl estradiol on the differentiation of mouse fetal testis
    • Yasuda, Y., Kihara, T. and Tanimura, T. (1985a) Effect of ethinyl estradiol on the differentiation of mouse fetal testis. Teratology, 32, 113-118.
    • (1985) Teratology , vol.32 , pp. 113-118
    • Yasuda, Y.1    Kihara, T.2    Tanimura, T.3
  • 58
    • 0021931189 scopus 로고
    • Gonadal dysgenesis induced by prenatal exposure to ethinyl estradiol in mice
    • Yasuda, Y., Kihara, T., Tanimura, T. et al. (1985b) Gonadal dysgenesis induced by prenatal exposure to ethinyl estradiol in mice. Teratology, 32, 219-227.
    • (1985) Teratology , vol.32 , pp. 219-227
    • Yasuda, Y.1    Kihara, T.2    Tanimura, T.3
  • 59
    • 0022472779 scopus 로고
    • Accelerated differentiation in seminiferous tubules of fetal mice prenatally exposed to ethinyl estradiol
    • Yasuda, Y., Konishi, H., Matuso, T. et al. (1986a) Accelerated differentiation in seminiferous tubules of fetal mice prenatally exposed to ethinyl estradiol. Anat. Embryol., 174, 289-299.
    • (1986) Anat. Embryol. , vol.174 , pp. 289-299
    • Yasuda, Y.1    Konishi, H.2    Matuso, T.3
  • 60
    • 0022460332 scopus 로고
    • Leydig cell hyperplasia in fetal mice treated transplacentally with ethinyl estradiol
    • Yasuda, Y., Konishi, H. and Tanimura, T. (1986b) Leydig cell hyperplasia in fetal mice treated transplacentally with ethinyl estradiol. Teratology, 33, 281-288.
    • (1986) Teratology , vol.33 , pp. 281-288
    • Yasuda, Y.1    Konishi, H.2    Tanimura, T.3
  • 61
    • 0023620034 scopus 로고
    • Ovarian follicular cell hyperplasia in fetal mice treated transplacenlally with ethinyl estradiol
    • Yasuda, Y., Konish, H. and Tanimura, T. (1987) Ovarian follicular cell hyperplasia in fetal mice treated transplacenlally with ethinyl estradiol. Teratology, 36, 35-43.
    • (1987) Teratology , vol.36 , pp. 35-43
    • Yasuda, Y.1    Konish, H.2    Tanimura, T.3
  • 62
    • 0024261643 scopus 로고
    • Long-term effects on male reproductive organs of prenatal exposure to ethinyl estradiol
    • Yasuda, Y., Ohara, I., Konishi, H. et al. (1988) Long-term effects on male reproductive organs of prenatal exposure to ethinyl estradiol. Am. J. Obstet. Gynecol., 159, 1246-1250.
    • (1988) Am. J. Obstet. Gynecol. , vol.159 , pp. 1246-1250
    • Yasuda, Y.1    Ohara, I.2    Konishi, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.