Interaction energies between β-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation

Protein Science

Volumn 10, Issue 6, 2001, Pages 1254-1259

  Beadle, Beth M ^a   Nicholas, Robert A ^b   Shoichet, Brian K ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

lactam; lactamase; Denaturation; Enzyme stability; PBP 5; Penicillin binding protein

Indexed keywords

BETA LACTAM ANTIBIOTIC; PENICILLIN BINDING PROTEIN;

ACYLATION; ARTICLE; BACTERIAL CELL WALL; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; COVALENT BOND; ENZYME STABILITY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN PROTEIN INTERACTION; THERMAL INJURY;

ACYLATION; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMS; CARRIER PROTEINS; CEFOXITIN; CIRCULAR DICHROISM; CLOXACILLIN; ESCHERICHIA COLI; HEXOSYLTRANSFERASES; IMIPENEM; MODELS, CHEMICAL; MOXALACTAM; MURAMOYLPENTAPEPTIDE CARBOXYPEPTIDASE; PENICILLIN-BINDING PROTEINS; PEPTIDYL TRANSFERASES; PROTEIN BINDING; PROTEIN DENATURATION; SPECTROMETRY, FLUORESCENCE; TEMPERATURE; THERMODYNAMICS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0035019658     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.52001     Document Type: Article

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