메뉴 건너뛰기




Volumn 297, Issue 3, 2001, Pages 1193-1200

Pulmonary bioactivation of 1,1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2E1; EPOXIDE; GLUTATHIONE DERIVATIVE; VINYLIDENE CHLORIDE;

EID: 0035017698     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (13)

References (32)
  • 1
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Chem 72:248-254.
    • (1976) Anal Chem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 2
    • 0017741869 scopus 로고
    • Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung
    • Boyd MR (1977) Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung. Nature (Lond) 269:713-715.
    • (1977) Nature (Lond) , vol.269 , pp. 713-715
    • Boyd, M.R.1
  • 3
    • 0018824250 scopus 로고
    • The pulmonary Clara cells as a target for toxic chemicals requiring metabolic activation: Studies with carbon tetrachloride
    • Boyd MR, Statham CN and Longo NS (1980) The pulmonary Clara cells as a target for toxic chemicals requiring metabolic activation: studies with carbon tetrachloride. J Pharmacol Exp Ther 212:109-114.
    • (1980) J Pharmacol Exp Ther , vol.212 , pp. 109-114
    • Boyd, M.R.1    Statham, C.N.2    Longo, N.S.3
  • 5
    • 0021674075 scopus 로고
    • Chlorinated ethylenes: Their metabolism and effect on DNA repair in hepatocytes
    • Costa AK and Invanetich KM (1984) Chlorinated ethylenes: their metabolism and effect on DNA repair in hepatocytes. Carcinogenesis 5:1629-1636.
    • (1984) Carcinogenesis , vol.5 , pp. 1629-1636
    • Costa, A.K.1    Invanetich, K.M.2
  • 6
    • 0028901298 scopus 로고
    • Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene
    • Dowsley TF, Forkert PG, Benesch LA and Bolton JL (1995) Reaction of glutathione with the electrophilic metabolites of 1,1-dichloroethylene. Chem-Biol Interact 95: 227-244.
    • (1995) Chem-biol Interact , vol.95 , pp. 227-244
    • Dowsley, T.F.1    Forkert, P.G.2    Benesch, L.A.3    Bolton, J.L.4
  • 7
    • 0030200743 scopus 로고    scopus 로고
    • CYP2E1-dependent bioactivation of 1,1-dichloroethylene in marine lung: Formation of reactive intermediates and glutathione conjugates
    • Dowsley TF, Ulreich JB, Bolton JL, Park SS and Forkert PG (1996) CYP2E1-dependent bioactivation of 1,1-dichloroethylene in marine lung: formation of reactive intermediates and glutathione conjugates. Toxicol Appl Pharmacol 139:42-48.
    • (1996) Toxicol Appl Pharmacol , vol.139 , pp. 42-48
    • Dowsley, T.F.1    Ulreich, J.B.2    Bolton, J.L.3    Park, S.S.4    Forkert, P.G.5
  • 8
    • 0023079953 scopus 로고
    • High performance liquid chromatography of thiols and disulfides: Dinitrophenol derivatives
    • Fariss MW and Reed DJ (1987) High performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives. Methods Enzymol 143:101-109.
    • (1987) Methods Enzymol , vol.143 , pp. 101-109
    • Fariss, M.W.1    Reed, D.J.2
  • 9
    • 0022402790 scopus 로고
    • Bromobenzene causes Clara cell damage in mice
    • Forkert PG (1985) Bromobenzene causes Clara cell damage in mice. Can J Physiol Pharmacol 63:1480-1484.
    • (1985) Can J Physiol Pharmacol , vol.63 , pp. 1480-1484
    • Forkert, P.G.1
  • 10
    • 0029321404 scopus 로고
    • CYP2E1 is preferentially expressed in clara cells of murine lung: Localization by in situ and immunohistochemical methods
    • Forkert PG (1995) CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ and immunohistochemical methods. Am J Respir Cell Mol Biol 12:589-596.
    • (1995) Am J Respir Cell Mol Biol , vol.12 , pp. 589-596
    • Forkert, P.G.1
  • 11
    • 0033141454 scopus 로고    scopus 로고
    • 1,1-dichloroethylene-induced Clara cell damage is associated with in situ formation of the reactive epoxide
    • Forkert PG (1999) 1,1-Dichloroethylene-induced Clara cell damage is associated with in situ formation of the reactive epoxide. Am J Respir Cell Mol Biol 20:1310-1318.
    • (1999) Am J Respir Cell Mol Biol , vol.20 , pp. 1310-1318
    • Forkert, P.G.1
  • 12
    • 0030976989 scopus 로고    scopus 로고
    • Immunochemical assay for recognition of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1,1-dichloroethylene-epoxide
    • Forkert PG, Collins KS, Dowsley TF and Ross GM (1997) Immunochemical assay for recognition of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1,1-dichloroethylene-epoxide. J Pharmacol Exp Ther 281:1422-1430.
    • (1997) J Pharmacol Exp Ther , vol.281 , pp. 1422-1430
    • Forkert, P.G.1    Collins, K.S.2    Dowsley, T.F.3    Ross, G.M.4
  • 13
    • 0030425572 scopus 로고    scopus 로고
    • Differential formation of 1,1-dichloroethylene-metabolites in the lungs of adult and weanling male and female mice: Correlation with severities of bronchiolar cytotoxicity
    • Forkert PG, Dowsley TF, Lee RP, Hong J-Y and Ulreich JB (1996a) Differential formation of 1,1-dichloroethylene-metabolites in the lungs of adult and weanling male and female mice: correlation with severities of bronchiolar cytotoxicity. J Pharmacol Exp Ther 279:1484-1490.
    • (1996) J Pharmacol Exp Ther , vol.279 , pp. 1484-1490
    • Forkert, P.G.1    Dowsley, T.F.2    Lee, R.P.3    Hong, J.-Y.4    Ulreich, J.B.5
  • 14
    • 0025354245 scopus 로고
    • Morphologic changes and covalent binding of 1,1-dichloroethylene in Clara and alveolar type II cells isolated from lungs of mice following in vivo administration
    • Forkert PG, Geddes BA, Birch DW and Massey TE (1990) Morphologic changes and covalent binding of 1,1-dichloroethylene in Clara and alveolar type II cells isolated from lungs of mice following in vivo administration. Drug Metab Dispos 18:534-539.
    • (1990) Drug Metab Dispos , vol.18 , pp. 534-539
    • Forkert, P.G.1    Geddes, B.A.2    Birch, D.W.3    Massey, T.E.4
  • 15
    • 0023205998 scopus 로고
    • Metabolic activation of 1,1-dichloroethylene by mouse lung and liver microsomes
    • Forkert PG, Hofley M and Racz WJ (1987) Metabolic activation of 1,1-dichloroethylene by mouse lung and liver microsomes. Can J Physiol Pharmacol 65:1496-1499.
    • (1987) Can J Physiol Pharmacol , vol.65 , pp. 1496-1499
    • Forkert, P.G.1    Hofley, M.2    Racz, W.J.3
  • 16
    • 0030434541 scopus 로고    scopus 로고
    • Protection from 1,1-dichloroethylene-induced Clara cell injury by diallyl sulfone, a derivative of garlic
    • Forkert PG, Lee RP, Dowsley TF, Hong J-Y and Ulreich JB (1996b) Protection from 1,1-dichloroethylene-induced Clara cell injury by diallyl sulfone, a derivative of garlic. J Pharmacol Exp Ther 277:1665-1671.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 1665-1671
    • Forkert, P.G.1    Lee, R.P.2    Dowsley, T.F.3    Hong, J.-Y.4    Ulreich, J.B.5
  • 18
    • 0028222128 scopus 로고
    • Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration
    • Forkert PG, Redza ZM, Mangos S, Park SS and Tam S-P (1994) Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration. Drug Metab Dispos 22:248-253.
    • (1994) Drug Metab Dispos , vol.22 , pp. 248-253
    • Forkert, P.G.1    Redza, Z.M.2    Mangos, S.3    Park, S.S.4    Tam, S.-P.5
  • 19
    • 0020062154 scopus 로고
    • 1,1-dichloroethylene-induced pulmonary injury
    • Forkert PG and Reynolds ES (1982) 1,1-Dichloroethylene-induced pulmonary injury. Exp Lung Res 3:57-68.
    • (1982) Exp Lung Res , vol.3 , pp. 57-68
    • Forkert, P.G.1    Reynolds, E.S.2
  • 21
    • 0023201483 scopus 로고
    • Inhibition and induction of rabbit liver microsomal cytochrome P-450 by pyridine
    • Kaul KL and Novak RF (1987) Inhibition and induction of rabbit liver microsomal cytochrome P-450 by pyridine. J Pharmacol Exp Ther 243:384-390.
    • (1987) J Pharmacol Exp Ther , vol.243 , pp. 384-390
    • Kaul, K.L.1    Novak, R.F.2
  • 22
    • 0022494453 scopus 로고
    • Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a
    • Koop DR (1986) Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a. Mol Pharmacol 29:399-404.
    • (1986) Mol Pharmacol , vol.29 , pp. 399-404
    • Koop, D.R.1
  • 23
    • 0028926741 scopus 로고
    • Pulmonary CYP2E1 bioactivates 1,1-dichloroethylene in male and female mice
    • Lee RP and Forkert PG (1995) Pulmonary CYP2E1 bioactivates 1,1-dichloroethylene in male and female mice. J Pharmcol Exp Ther 273:561-567.
    • (1995) J Pharmcol Exp Ther , vol.273 , pp. 561-567
    • Lee, R.P.1    Forkert, P.G.2
  • 24
    • 0021047310 scopus 로고
    • Olefin oxidation by cytochrome P-450: Evidence for group migration in catalytic intermediates formed with vinylidene chloride and trans-1-phenyl-1-butene
    • Liebler DC and Guengerich FP (1983) Olefin oxidation by cytochrome P-450: evidence for group migration in catalytic intermediates formed with vinylidene chloride and trans-1-phenyl-1-butene. Biochemistry 22:5482-5489.
    • (1983) Biochemistry , vol.22 , pp. 5482-5489
    • Liebler, D.C.1    Guengerich, F.P.2
  • 25
    • 0023911064 scopus 로고
    • S(2-chloroacetyl)glutathione, a glutathione thiol ester and putative metabolite of 1,1-dichloroethylene
    • Liebler DC, Latwesen DG and Reeder TC (1988) S(2-Chloroacetyl)glutathione, a glutathione thiol ester and putative metabolite of 1,1-dichloroethylene. Biochemistry 27:3652-3657.
    • (1988) Biochemistry , vol.27 , pp. 3652-3657
    • Liebler, D.C.1    Latwesen, D.G.2    Reeder, T.C.3
  • 26
    • 0021934593 scopus 로고
    • Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes
    • Liebler DC, Meredith MJ and Guengerich FP (1985) Formation of glutathione conjugates by reactive metabolites of vinylidene chloride in microsomes and isolated hepatocytes. Cancer Res 45:186-193.
    • (1985) Cancer Res , vol.45 , pp. 186-193
    • Liebler, D.C.1    Meredith, M.J.2    Guengerich, F.P.3
  • 28
    • 0017348354 scopus 로고
    • Morphology of a naphthalene-induced bronchiolar lesion
    • Mahvi D, Band H and Harley R (1977) Morphology of a naphthalene-induced bronchiolar lesion. Am J Pathol 86:559-572.
    • (1977) Am J Pathol , vol.86 , pp. 559-572
    • Mahvi, D.1    Band, H.2    Harley, R.3
  • 29
    • 0026511385 scopus 로고
    • 1,1-dichloroethylene-induced alterations in glutathione and covalent binding in murine lung: Morphological, histochemical, and biochemical studies
    • Moussa M and Forkert PG (1992) 1,1-Dichloroethylene-induced alterations in glutathione and covalent binding in murine lung: morphological, histochemical, and biochemical studies. J Pathol 166:199-207.
    • (1992) J Pathol , vol.166 , pp. 199-207
    • Moussa, M.1    Forkert, P.G.2
  • 30
    • 0022443227 scopus 로고
    • 14C]1,1-dichloroethylene by mouse liver, kidney and lung
    • 14C]1,1-dichloroethylene by mouse liver, kidney and lung. Biochem Pharmacol 35:2789-2794.
    • (1986) Biochem Pharmacol , vol.35 , pp. 2789-2794
    • Okine, K.1    Gram, T.E.2
  • 32
    • 0018852015 scopus 로고
    • Cytochrome P-450: Localization in rabbit lung
    • Wash DC
    • Serabjit-Singh CJ, Wolf CR and Philpot RM (1980) Cytochrome P-450: localization in rabbit lung. Science (Wash DC) 207:1469-1473.
    • (1980) Science , vol.207 , pp. 1469-1473
    • Serabjit-Singh, C.J.1    Wolf, C.R.2    Philpot, R.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.