Synthesis of (7S,15S)- and (7R,15S)-dolatrienoic acid

Journal of Natural Products

Volumn 64, Issue 4, 2001, Pages 472-479

  Duffield, Jonathan J ^a   Pettit, George R ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; DOLASTATIN 14; DOLATRIENOIC ACID; OXAZOLIDINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHIRALITY; CONTROLLED STUDY; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOLLUSC; STEREOSPECIFICITY;

ALKENES; ANIMALS; MOLECULAR STRUCTURE; MOLLUSCA; PEPTIDES, CYCLIC; SPECTRUM ANALYSIS; STEREOISOMERISM;

MOLLUSCA;

EID: 0035013577     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np000502q     Document Type: Article

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17. Phenyllithium was freshly prepared before each reaction by the addition of an ethereal solution of bromobenzene to 2 equiv of lithium in ether. Excess lithium was removed by filtration through glass wool under an argon atmosphere. The solution was titrated against diphenylacetic acid.