Effect of intranasal challenge with interleukin-6 on upper airway symptomatology and physiology in allergic and nonallergic patients

Annals of Allergy, Asthma and Immunology

Volumn 86, Issue 5, 2001, Pages 531-536

  Gentile, Deborah A ^a   Yokitis, John ^a   Angelini, Betty L ^a   Doyle, William J ^a   Skoner, David P ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6;

ADULT; ALLERGIC RHINITIS; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; CROSSOVER PROCEDURE; DIAGNOSTIC VALUE; DOUBLE BLIND PROCEDURE; DRUG TOLERABILITY; FEMALE; HUMAN; MALE; NOSE SECRETION; PRIORITY JOURNAL; PROVOCATION TEST; SNEEZING; SYMPTOMATOLOGY; UPPER RESPIRATORY TRACT INFECTION;

EID: 0035013186     PISSN: 10811206     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)62901-8     Document Type: Article

References (34)

1. Gwaltney JM. Upper respiratory infections, the common cold. In: Mandell GL, Bennet JE, Dolin R, eds. Principles and Practice of Infectious Diseases, 4th ed. New York: Churchill Livingstone, 1995:561-566.
2. Gwaltney JM. Rhinovirus infection of the normal human airway. Am J Respir Crit Care Med 1995;152:S36-S39.
3. Turner RB. Epidemiology, pathogenesis, and treatment of the common cold. Ann Allergy Asthma Immunol 1997; 78:531-538.
4. Naclerio RM, Proud D, Lichtenstein LM, et al. Kinins are generated during experimental rhinovirus colds. J Infect Dis 1988;157:133-142.
5. Igarashi Y, Skoner DP, Doyle WJ, et al. Analysis of nasal secretions during phases of experimental rhinovirus upper respiratory tract infection. J Allergy Clin Immunol 1993;92:722-731.
6. Doyle WJ, Skoner DP, White MV, et al. Pattern of nasal secretions during experimental influenza virus infection. Rhinology 1996;34:2-8.
7. Smith H, Sweet C. Lessons for human influenza from pathogenicity studies with ferrets. Rev Infect Dis 1988;10: 56-75.
8. Yuta A, Gaumond E, Ali M, et al. Rhinovirus infection induces mucus hypersecretion. Am J Physiol 1998; 274:1017-1023.
9. Arnold R, Humbert B, Werchau H, et al. Interleukin-8, interleukin-6, and soluble necrosis factor receptor type I release from a human pulmonary epithelial cell line (AS49) exposed to respiratory syncytial virus. Immunology 1994;82:126-133.
10. Subauste MC, Jacoby D, Richards S, Proud D. Induction of cytokine release and modulation of susceptibility to infection by cytokine exposure. J Clin Invest 1995;96:549-557.
11. Matsukura S, Kokubu F, Noda H, et al. Expression of IL-6, IL-8 and RANTES on human bronchial epithelial cells, NCI-H292, induced by influenza virus A. J Allergy Clin Immunol 1996;98: 1080-1087.
12. Noah TL, Henderson FW, Wortman IA, et al. Nasal cytokine production in viral acute upper respiratory infection of childhood. J Infect Dis 1995;171: 584-592.
13. Hayden FG, Fritz R, Lobo MC, et al. Local and systemic cytokine responses during experimental human influenza A virus infection: relation to symptom formation and host defense. J Clin Invest 1998;101:643-649.
14. Gentile D, Doyle W, Whiteside T, et al. Increased interleukin-6 levels in nasal lavage samples following experimental influenza A virus infection. Clin Diagn Lab Immunol 1998;5:604-608.
15. Skoner DP, Gentile DA, Patel A, Doyle WJ. Evidence for cytokine mediation of disease expression in adults experimentally infected with influenza A virus. J Infect Dis 1999;180:10-14.
16. Cohen S, Doyle WJ, Skoner DP. Psychological stress, cytokine production and severity of upper respiratory illness. Psychosom Med 1999;61:175-180.
17. Borish L, Rosenwasser LJ. Update on cytokines. J Allergy Clin Immunol 1996;97:719-734.
18. Longhi SA, Miranda ME, Gobet MG, Retegui, LA. A monoclonal antibody recognizing an epitope shared by receptors for growth hormone, prolactin, interleukin 2 and interleukin 6. Mol Cell Biochem 1999;195:235-243.
19. Doyle WJ, Skoner DP, Seroky JT, et al. Effect of rhinovirus-39 infection on the nasal response to histamine and cold air challenges in allergic and non-allergic subjects. J Allergy Clin Immunol 1994;92:534-542.
20. Doyle WJ, Boehm S, Skoner DP. Physiologic responses to intranasal dose-response challenges with histamine, methacholine, bradykinin and prostaglandin in adult volunteers with and without nasal allergy. J Allergy Clin Immunol 1990;86:924-935.
21. Bisgaard H, Olsson P, Bende M. Effect of leukotriene D4 on mucosal blood flow, nasal airway resistance and nasal secretions in humans. Clin Allergy 1986;16:289-297.
22. Terada N, Konno A, Tada H, et al. The effect of recombinant human interleukin-5 on eosinophil accumulation and degranulation in human nasal mucosa. J Allergy Clin Immunol 1992;90: 160-168.
23. Douglass JA, Dhami D, Gurr C, et al. Influence of interleukin-8 challenge in the nasal mucosa in atopic and nonatopic subjects. Am J Respir Crit Care Med 1994;150:1108-1113.
24. Skoner D, Doyle W, Tanner E, et al. Effect of rhinovirus 39 infection on immune and inflammatory parameters in allergic and non-allergic subjects. Clin Exp Allergy 1995;24:561-567.
25. Skoner D, Whiteside T, Wilson J. Effect of rhinovirus 39 infection on cellular immune parameters in allergic and nonallergic subjects. J Allergy Clin Immunol 1993;92:732-743.
26. Rampart M, Van Damme J, Zonnekeyn L, et al. Granulocyte chemotactic protein/interleukin-8 induces plasma leakage and neutrophil accumulation in rabbit skin. Am J Pathol 1989;135:21-25.
27. Doyle WJ, Skoner DP, Hayden F, et al. Nasal and otologic effects of experimental influenza A virus infection. Ann Otol Rhinol Laryngol 1994;103:59-69.
28. in't Veen JC, Smits HH, Hiemstra PS, et al. Lung function and sputum characteristics of patients with severe asthma during an induced exacerbation by double-blind steroid withdrawal. Am J Respir Crit Care Med 1999;160:93-99.
29. Tillie-Leblond I, Pugin J, Marquette CH, et al. Balance between proinflammatory cytokines and their inhibitors in bronchial lavage from patients with status asthmaticus. Am J Respir Crit Care Med 1999;159:487-494.
30. 4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast or an interleukin-5 monoclonal antibody. Am J Respir Crit Care Med 1996;154:850-857.
31. Serhan CN, Haeggstrom JZ, Leslie CC. Lipid mediator networks in cell signaling: update and impact of cytokines. FASEB J 1996;10:1147-1158.
32. Turner RB, Weingand KW, Yeh CH, Leedy DW. Association between interleukin-8 concentration in nasal secretions and severity of symptoms of experimental rhinovirus colds. Clin Infect Dis 1998;26:840-846.
33. Proud D, Gwaltney JM, Hendley JO, et al. Increased levels of interleukin-1 are detected in nasal secretions of volunteers during experimental rhinovirus colds. J Infect Dis 1994;169:1007-1013.
34. Teran LM, Johnston SL, Schroder JM, et al. Role of nasal interleukin-8 in neutrophil recruitment and activation in children with virus-induced asthma. Am J Respir Crit Care Med 1997;155: 1362-1366.