Monoclonal light chain-mesangial cell interactions: Early signaling events and subsequent pathologic effects

Laboratory Investigation

Volumn 81, Issue 5, 2001, Pages 689-703

  Russell, William J ^a   Cardelli, James ^a   Harris, Edward ^a   Baier, R John ^a   Herrera, Guillermo A ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN LIGHT CHAIN; KI 67 ANTIGEN; MONOCYTE CHEMOTACTIC PROTEIN 1; PLATELET DERIVED GROWTH FACTOR; PROTEIN C FOS;

AMYLOIDOSIS; ARTICLE; CELL INTERACTION; CELL SHAPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; KIDNEY DISEASE; MESANGIUM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0035011613     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3780278     Document Type: Article

References (40)

1. Abboud HE (1991). Mesangial cells in glomerular injury. Semin Nephrol 11:299-306.
2. Abboud HE (1993). Growth factors in glomerulonephritis. Kidney Intl 43:252-367.
3. Auwardt RB, Mudge SJ, Chen CG, and Power DA (1998). Regulation of nuclear factor-κβ by corticosteroids in rat mesangial cells. J Am Soc Nephrol 9:1620-1628.
4. Batuman V and Guan S (1997). Receptor-mediated endocytosis of immunoglobulin light chains by renal proximal tubule cells. Am J Physiol 272:F521-F530.
5. Batuman V, Verroust PJ, Navar G, Kaysen JH, Goda FO, Campbell WC, Simon E, Pontillon F, Lyles M, Bruno J, and Hammond TG (1998). Myeloma light chains are ligands for cubilin (gp280). Am J Physiol 275:F246-F254.
6. Border WA, Noble NA, Yamamoto T, Tomooka S, and Kagami S (1992). Antagonists of transforming growth factor-β: A novel approach to treatment of glomerulonephritis and prevention of glomerulosclerosis. Kidney Int 41:566-570.
7. Böttinger EP, Letterio JJ, and Roberts AB (1997). Biology of TGF-β in knockout and transgenic mouse models. Kidney Int 51:1355-1360.
8. Duque N, Gomez-Guerro C, and Egido J (1997). Interactin of IgA with Fc α receptors of human mesangial cells activates transcription factor nuclear factor-κβ and induces expression and synthesis of monocyte chemoattractant protein-1, IL-8, and IFN-inducible protein 10. J Immunol 159:3474-3482.
9. Feige JJ and Baird A (1995). Crinopexy: Extracellular regulation of growth factor action. Kidney Int 49(Suppl):S15-S18.
10. Gallo G, Picken M, Buxbaum J, and Frangione B (1989). The spectrum of monoclonal immunoglobulin deposition disease associated with immunocytic dyscrasias. Semin Hematol 26:234-245.
11. Harper PA, Robinson JM, Hoover RL, Wright TC, and Karaovsky MJ (1984). Improved methods for cultured rat glomerular cell. Kidney Int 26:875-880.
12. Herrera GA, Russell WJ, Isaac J, Turbat-Herrera EA, Tagouri YM, Sanders PW, Picken MM, and Dempsey S (1999). Glomerulopathic light chain-mesangial cell interactions modulate in vitro extracellular matrix remodeling and reproduce mesangiopathic findings documented in vivo. Ultrastruct Pathol 23:107-126.
13. Herrera GA, Shultz J, Soong S, and Sanders PW (1994). Growth factors in monoclonal light chain related renal diseases. Hum Pathol 25:883-892.
14. Hsu S-M, Raine L, and Fanger H (1981). Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J Histochem Cytochem 29:577-580.
15. Ishikawa Y, Sugiyama H, Stylianou E, and Kitamura M (1999). Bioflavanoid quercetin inhibits interleukin-1-induced transcriptional expression of monocyte chemoattractant protein-1 in glomerular cells via suppression of nuclear factor-κβ. J Am Soc Nephrol 10:2290-2296.
16. Kon A, Vindevoghel L, Kouba DJ, Fujimura Y, Uitto J, and Mauviel A (1999). Cooperation between SMAD and NF-κβ in growth factor regulated type VII collagen gene expression. Oncogene 18:1837-1844.
17. Kopp JB, Factor VM, Mozes M, Nagy P, Sanderson N, Böttinger EP, Klotman PE, and Thorgeirsson SS (1996). Transgenic mice with increased plasma levels of TGF-β1 develop progressive renal disease. Lab Invest 74:991-1003.
18. Lawrence DA (1995). Transforming growth factor-β: An overview. Kidney Int 47:519-23.
19. Lipkowitz JS, Klotman ME, Bruggeman LA, Nicklin P, Hanss B, Rappaport J, and Klotman PE (1996). Molecular therapy for renal diseases. Am J Kidney Dis 28:475-492.
20. López-Armada MJ, Gómez-Guerrero C, and Egido J (1996). Receptors for immune complexes activate gene expression and synthesis of matrix proteins in cultured rat and human mesangial cells: Role of TGF-β. J Immunol 157:2136-2142.
21. Massy ZA, Guijarro C, O'Donnell MP, Kim Y, Kashtan CE, Egido J, Kasiske BL, and Keane WF (1999). The central role of nuclear factor-κβ in mesangial cell activation. Kidney Int 71(Suppl):S76-79.
22. Mellström K, Heldin CH, and Westermark B (1988). Induction of circular membrane ruffling on human fibroblasts by platelet-derived growth factor. Exp Cell Res 177:347-359.
23. Peters H, Border WA, and Noble NA (1998). Targeting TGF-β overexpression in renal disease: Maximizing the antifibrotic action of angiotensin Il blockade. Kidney Int 54:1570-1580.
24. Poncelet AC and Schnaper HW (1998). Regulation of human mesangial cell collagen expression by transforming growth factor-β1. Am J Physiol 275:F458-F466.
25. Richards SA, Fu J, Romanelli A, Shimamura A, and Blenis J (1999). Ribosomal S6 kinase 1 (RSK1) activation requires signal dependent on and independent of the MAP kinase ERK. Current Biol 9:810-820.
26. Rovin BH, Dickerson JA, Tan LC, and Hebert CA (1995). Activation of nuclear factor κβcorrelates with MCP-1 expression by human mesangial cells. Kidney Int 48:1263-1271.
27. Rovin BH, Wilmer WA, Danne M, Dickerson JA, Dixon CL, and Lu L (1999). The mitogen-activated protein kinase p38 is necessary for interleukin 1 beta-induced monocyte chemoattractant protein 1 expression by human mesangial cells. Cytokine 11:118-126.
28. Ruiz-Ortega M, Bustos C, Hernandez-Presa MA, Lorenzo O, Plaza JJ, and Egido J (1998). Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-κβ activation and monocyte chemoattractant protein-1 synthesis. J Immunol 161:430-439.
29. Sanders PW and Herrera GA (1993). Monoclonal immunoglobulin light chain-related renal diseases. Semin Nephrol 13:324-341.
30. Sanders PW, Herrera GA, and Galla JH (1987). Human Bence Jones protein toxicity in rat proximal tubule epithelium in vivo. Kidney Int 32:851-861.
31. Sanders PW, Herrera GA, Kirk KA, Old CW, and Galla JH (1991). The spectrum of glomerular and tubulointerstitial renal lesions associated with monotypical immunoglobulin light chain deposition. Lab Invest 64:527-537.
32. Satriano J and Schlondorff D (1994). Activation and attenuation of transcription factor NF-κβ in some glomerular mesangial cells in response to tumor necrosis factor-α, immunoglobulin G, and adenosine 3′-5′-cyclic monophosphate. J Clin Invest 94:1629-1636.
33. Schreiber E, Matthias P, Müller MM, and Schaffner W (1989). Rapid detection of octamer binding proteins with "mini extracts," prepared from a small number of cells. Nucleic Acids Res 17:6419.
34. Sharma K and Ziyadeh FN (1993). The transforming growth factor-β system and the kidney. Semin Nephrol 13:116-128.
35. Stylianou E, Nie M, Ueda A, and Zhao L (1999). c-Rel and p65 trans-activate the monocyte chemoattractant protein-1 gene in interleukin-1 stimulated mesangial cells. Kidney Int 56: 873-882.
36. Tagouri YM, Sanders PW, Picken MM, Siegal GP, Kerby JD, and Herrera GA (1996). In vitro AL-amyloid formation by rat and human mesangial cells. Lab Invest 74:290-302.
37. Valenzuela R and Deodhar SD (1986). Tissue immunofluorescence. In: Rose NR, Friedman H, Fahey JL, editors. Manual of clinical laboratory immunology, 3rd ed. Washington: American Society for Microbiology, 923-925.
38. Whitman M (1998). Smads and early developmental signaling by the TGFβ family. Genes Dev 12:2445-2462.
39. Van SD, Zhu H, Zhu A, Golabek A, Du H, Roher A, Yu J, Soto C, Schmidt AM, Stern D, and Kindy M (2000). Receptor-dependent cell stress and amyloid accumulation in systemic amyloidosis. Nat Med 16:643-651.
40. Zhu L, Herrera GA, Murphy-Ullrich JE, Huang Z-Q, and Sanders PW (1995). Pathogenesis of glomerulosclerosis in light chain deposition disease: Role for transforming growth factor-β. Am J Pathol 147:375-385.