Endotoxin responsiveness and subchronic grain dust-induced airway disease

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 280, Issue 2 24-2, 2001, Pages

  George, Caroline L S ^a   Jin, Hong ^a   Wohlford Lenane, Christine L ^a   O'Neill, Marsha E ^b   Phipps, John C ^b   O'Shaughnessy, Patrick ^b   Kline, Joel N ^a   Thorne, Peter S ^b   Schwartz, David A ^a,c  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Airway remodeling; Asthma; Environmental exposure; Genetics

Indexed keywords

CYTOKINE; ENDOTOXIN; INTERLEUKIN 6; MESSENGER RNA; METHACHOLINE; TUMOR NECROSIS FACTOR ALPHA;

AGED; AIRWAY RESISTANCE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CONTROLLED STUDY; CORN; ENVIRONMENTAL EXPOSURE; GRAIN DUST; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0035009445     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.280.2.l203     Document Type: Article

References (73)

1. Akashi S, Shimazu R, Ogata H, Nagai Y, Takeda K, Kimoto M, and Miyake K. Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages. J Immunol 164: 3471-3475, 2000.
2. Baluska F, Samaj J, Volkmann D, and Barlow P. Impact of taxol-mediated stabilization of microtubules on nuclear morphology, ploidy levels and cell growth in maize roots. Biol Cell 89: 221-231, 1997.
3. Beck GJ, Schachter EN, Maunder LR, and Schilling RSR. A prospective study of chronic lung disease in cotton textile workers. Ann Intern Med 97: 645-651, 1982.
4. Becker S, Soukup JM, Gilmour MI, and Devlin RB. Stimulation of human and rat alveolar macrophages by urban air particulates: effects on oxidant radical generation and cytokine production. Toxicol Appl Pharmacol 141: 637-648, 1996.
5. Beutler B, Tkacenko V, Milsark I, Krochin N, and Cerami A. Effect of gamma interferon on cachectin expression by mononuclear phagocytes: reversal of the lpsd (endotoxin resistance) phenotype. J Exp Med 164: 1791-1796, 1986.
6. Blainey AD, Topping MD, Ollier S, and Davies RJ. Allergic respiratory disease in grain workers: the role of storage mites. J Allergy Clin Immunol 84: 296-303, 1989.
7. Bonner JC, Rice AB, Lindroos PM, O'Brien PO, Dreher KL, Rosas I, Alfaro-Moreno E, and Osornio-Vargas AR. Induction of the lung myofibroblast PDGF receptor system by urban ambient particles from Mexico City. Am J Respir Cell Mol Biol 19: 672-680, 1998.
8. Boulet L, Laviolette M, Turcotte H, Cartier A, Dugas M, Malo J, and Boutet M. Bronchial subepithelial fibrosis correlates with airway responsiveness to methacholine. Chest 112: 45-52, 1997.
9. Brewster CEP, Howarth PH, Djukanovic R, Wilson J, Holgate ST, and Roche WR. Myofibroblasts and subepithelial fibrosis in bronchial asthma. Am J Respir Crit Care Med 3: 507-511, 1990.
10. Broder I, Hutcheon MA, Mintz S, Davies G, Leznoff A, Thomas P, and Corey P. Changes in respiratory variables of grain handlers and civic workers during their initial months of employment. Br J Ind Med 41: 94-99, 1984.
11. Castellan RM, Olenchock SA, Kinsely KB, and Hankinson JL. Inhaled endotoxin and decreased spirometric values: an exposure-response relation for cotton dust. N Engl J Med 317: 605-610, 1987.
12. Chan-Yeung M, Schulzer M, MacLean L, Dorken E, and Graybowski S. Epidemiologic health survey of grain elevator workers in British Columbia. Am Rev Respir Dis 121: 329-338, 1980.
13. Chan-Yeung M, Schulzer M, Maclean L, Dorken E, Tan F, Lam S, Enarson D, and Grzybowski S. A follow-up study of the grain elevator workers in the Port of Vancouver. Arch Environ Health 36: 75-81, 1981.
14. Chomczynski P and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
15. Chow JC, Young DW, Golenbock DT, Christ WJ, and Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem 274: 10689-10692, 1999.
16. Christiani D, Ye T, Zhang S, Wegman D, Eisen E, Ryan L, Olenchock S, Pothier L, and Dai H. Cotton dust and endotoxin exposure and long-term decline in lung function: results of a longitudinal study. Am J Ind Med 35: 321-331, 1999.
17. Christiani D, Ye T-T, Wegman D, Eisen E, Dai H-L, and Lu P-L. Cotton dust exposure, across-shift drop in FEV1, and five-year change in lung function. Am J Respir Crit Care Med 150: 1250-1255, 1994.
18. Clapp WD, Becker S, Quay J, Watt JL, Thorne PS, Frees KL, Zhang X, Lux CR, and Schwartz DA. Grain dust-induced airflow obstruction and inflammation of the lower respiratory tract. Am J Respir Crit Care Med 150: 611-617, 1994.
19. Cruz-Orive LM and Weibel ER. Sampling designs for stereology. J Microsc 122: 235-257, 1981.
20. Deetz DC, Jagielo PJ, Quinn TJ, Thorne PS, Bleuer SA, and Schwartz DA. The kinetics of grain dust-induced inflammation of the lower respiratory tract. Am J Respir Crit Care Med 155: 254-259, 1997.
21. Dockery DW, Pope CA, Xu X, Spengler JD, Ware JH, Fay ME, Ferris BG, and Speizer FE. An association between air pollution and mortality in six US cities. N Engl J Med 329: 1754-1759, 1993.
22. DoPico GA, Reddan W, Anderson S, Flaherty D, and Smalley E. Acute effects of grain dust exposure during a work shift. Am Rev Respir Dis 128: 399-404, 1983.
23. DoPico GA, Reddan W, Flaherty D, Tsiatis A, Peters ME, Rao P, and Rankin J. Respiratory abnormalities among grain handlers: a clinical, physiologic, and immunologic study. Am Rev Respir Dis 115: 915-927, 1977.
24. Dubin W, Martin TR, Swoveland P, Leturcq DJ, Moriarty AM, Tobias PS, Bleeker ER, Goldblum SE, and Hasday JD. Asthma and endotoxin: lipopolysaccharide-binding protein and soluble CD14 in bronchoalveolar compartment. Am J Physiol Lung Cell Mol Physiol 270: L736-L744, 1996.
25. El Karim MAA, El Rab MOG, Omer AA, and El Haimi YAA. Respiratory and allergic disorders in workers exposed to grain and flour dusts. Arch Environ Health 41: 297-301, 1986.
26. Fogelmark B, Goto H, Yuasa K, Marchat B, and Rylander R. Acute pulmonary toxicity of inhaled β-1, 3-glucan and endotoxin. Agents Actions 35: 50-56, 1992.
27. Glindmeyer HW, Lefante JJ, Jones RN, Rando RJ, and Weill H. Cotton dust and across-shift change in FEV1 as predictors of annual change in FEV1. Am J Respir Crit Care Med 149: 584-590, 1994.
28. Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, and Gelfand EW. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 156: 766-775, 1997.
29. Heine H, Kirschning C, Lien E, Monks B, Rothe M, and Golenbock D. Cutting edge: cells that carry a null allele for toll-like receptor 2 are capable of responding to endotoxin. J Immunol 162: 6971-6975, 1999.
30. Hobbs MV, Weigle WO, Noonan DJ, Torbett BE, McEvilly RJ, Koch RJ, Cardenas GJ, and Ernst DN. Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J Immunol 150: 3602-3614, 1993.
31. Hogg J, McLean T, Martin B, and Wiggs B. Erythrocyte transit and neutrophil concentration in the dog lung. J Appl Physiol 65: 1217-1225, 1988.
32. Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, and Akira S. Cutting edge: toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol 162: 3749-3752, 1999.
33. Hsieh T, Yu C, and Oberdorster G. Deposition and clearance models of Ni compounds in the mouse lung and comparisons with the rat models. Aerosol Sci Technol 31: 358-372, 1999.
34. Huy T, de Schipper K, Chan-Yeung M, and Kennedy SM. Grain dust and lung function. Dose-response relationships. Am Rev Respir Dis 144: 1314-1321, 1991.
35. Jagielo P, Thorne P, Kern J, Quinn T, and Schwartz D. Role of endotoxin in grain dust-induced lung inflammation in mice. Am J Physiol Lung Cell Mol Physiol 270: L1052-L1059, 1996.
36. Jagielo PJ, Quinn TJ, Qureshi N, and Schwartz DA. Grain dust-induced lung inflammation is reduced by Rhodobacter sphaeroides diphosphoryl lipid A. Am J Physiol Lung Cell Mol Physiol 274: L26-L31, 1998.
37. Jagielo PJ, Thorne PS, Watt JL, Frees KL, Quinn TJ, and Schwartz DA. Grain dust and endotoxin inhalation challenges produce similar inflammatory responses in normal subjects. Chest 110: 263-270, 1996.
38. Jeffrey PK, Wardlaw AJ, Nelson FC, Collins JV, and Kay AB. Bronchial biopsies in asthma: an ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis 140: 1745-1753, 1989.
39. Kawasaki K, Akashi S, Shimazu R, Yoshida T, Miyake K, and Nishijima M. Mouse toll-like receptor 4 MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by taxol. J Biol Chem 275: 2251-2254, 2000.
40. Kedzierski W and Porter JC. A novel non-enzymatic procedure for removing DNA template from RNA transcription mixtures. Biotechniques 10: 210-214, 1991.
41. Kennedy SM, Christiani DC, Eisen EA, Wegman DH, Greaves IA, Olenchock SA, Ye T-T, and Lu P-L. Cotton dust and endotoxin exposure-response relationships in cotton textile workers. Am Rev Respir Dis 135: 194-200, 1987.
42. Kennedy SM, Dimich-Ward H, Desjardins A, Kassam A, Vedal S, and Chan-Yeung M. Respiratory health among retired grain elevator workers. Am J Respir Crit Care Med 150: 59-65, 1994.
43. Kirschning CJ, Wesche H, Merrill Ayres T, and Rothe M. Human toll-like receptor 2 confers responsiveness to bacterial lipopolysaccharide. J Exp Med 188: 2091-2097, 1998.
44. Kline JN, Waldschmidt TJ, Businga TR, Lemish JE, Weinstock JV, Thorne PS, and Krieg AM. Cutting edge: modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma. J Immunol 160: 2555-2559, 1998.
45. Medzhitov R and Janeway CA. Innate immunity: the virtues of a nonclonal system of recognition. Cell 91: 295-298, 1997.
46. Michel O, Duchateau J, and Sergysels R. Effect of inhaled endotoxin on bronchial reactivity in asthmatic and normal subjects. J Appl Physiol 66: 1059-1064, 1989.
47. Michel O, Ginanni R, Duchateau J, Vertongen F, le Bon B, and Sergysels R. Domestic endotoxin exposure and clinical severity of asthma. Clin Exp Allergy 21: 441-448, 1991.
48. Michel O, Kips J, Duchateua J, Vertongen F, Robert L, Collet H, Pauwels R, and Sergysels R. Severity of asthma is related to endotoxin in house dust. Am J Respir Crit Care Med 154: 1641-1646, 1996.
49. Milton D, Amsel J, Reed C, Enright P, Brown L, Aughenbaugh G, and Morey P. Cross-sectional follow-up of a flu-like respiratory illness among fiberglass manufacturing employees: endotoxin exposure associated with two distinct sequelae. Am J Ind Med 28: 469-488, 1995.
50. 1 mRNA expression and airways fibrosis in bronchial asthma. Am J Respir Cell Mol Biol 17: 326-333, 1997.
51. Oberdörster G, Ferin J, and Lehnert B. Correlation between particle size, in vivo particle persistence, and lung injury. Environ Health Perspect 102, Suppl 5: 173-179, 1994.
52. Pahwa P, Senthilselvan A, McDuffie H, and Dosman J. Longitudinal estimates of pulmonary function decline in grain workers. Am J Respir Crit Care Med 150: 656-662, 1994.
53. Poltorak A, He X, Smirnova I, Liu M-Y, van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, and Beutler B. Defective LPS signaling in C3H/Hej and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282: 2085-2088, 1998.
54. Rankin J, Picarella D, Geba G, Temann U, Prasad B, DiCosmo B, Tarallo A, Stripp B, Whitsett J, and Flavell R. Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity. Proc Natl Acad Sci USA 93: 7821-7825, 1996.
55. Roche WR, Williams JH, Beasley R, and Holgate ST. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 11: 520-524, 1989.
56. Rosner B. Fundamentals of Biostatistics (3rd ed.). Boston, MA: PWS-Kent Publishing, 1990.
57. Ryan LK and Vermeulen MW. Alveolar macrophages from C3H/HeJ mice show sensitivity to endotoxin. Am J Respir Cell Mol Biol 12: 540-546, 1995.
58. Schwartz D, Thorne P, Jagielo P, White G, Bleuer S, and Frees K. Endotoxin responsiveness and grain dust-induced inflammation in the lower respiratory tract. Am J Physiol Lung Cell Mol Physiol 267: L609-L617, 1994.
59. Schwartz DA, Donham KJ, Olenchock SA, Popendorf W, van Fossen DS, Burmeister LF, and Merchant JA. Determinants of longitudinal changes in spirometric functions among swine confinement operators and farmers. Am J Respir Crit Care Med 151: 47-53, 1995.
60. Schwartz DA, Landas SK, Lassise DL, Burmeister LF, Hunninghake GW, and Merchant JA. Airway injury in swine confinement workers. Ann Intern Med 116: 630-635, 1992.
61. Schwartz DA, Thorne PS, Yagla SJ, Burmeister LF, Olenchock SA, Watt JL, and Quinn TJ. The role of endotoxin in grain dust-induced lung disease. Am J Respir Crit Care Med 152: 603-608, 1995.
62. Sun J and Chung K. Airway inflammation despite loss of bronchial hyper-responsiveness after multiple ozone exposures. Respir Med 91: 47-55, 1997.
63. Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, and Akira S. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11: 443-451, 1999.
64. Tang W, Geba GP, Zheng T, Ray P, Homer RJ, Kuhn C III, Flavell RA, and Elias JA. Targeted expression of IL-11 in the murine airway causes lymphocytic inflammation, bronchial remodeling, and airways obstruction. J Clin Invest 98: 2845-2853, 1996.
65. Thorne PS, Reynolds SJ, Milton DK, Bloebaum PD, Zhang X, Whitten P, and Burmeister LF. Field evaluation of endotoxin air sampling assay methods. Am Ind Hyg Assoc J 58: 792-799, 1997.
66. Tournoy K, Kps J, Schou C, and Pauwels R. Airway eosinophilia is not a requirement for allergen-induced airway hyperresponsiveness. Clin Exp Allergy 30: 79-85, 2000.
67. Wilson J and Li X. The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway. Clin Exp Allergy 27: 363-371, 1997.
68. Wohlford-Lenane C, Deetz D, and Schwartz D. Cytokine gene expression after inhalation of corn dust. Am J Physiol Lung Cell Mol Physiol 276: L736-L743, 1999.
69. Wright SD. Toll, a new piece in the puzzle of innate immunity. J Exp Med 189: 605-609, 1999.
70. Yach D, Myers J, Bradshaw D, and Benatar SR. A respiratory epidemiologic survey of grain mill workers in Cape Town, South Africa. Am Rev Respir Dis 131: 505-510, 1985.
71. Yang RB, Mark MR, Gray A, Huang A, Xie MH, Zhang M, Goddard A, Wood WI, Gurney AL, and Godowski PJ. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signaling. Nature 395: 284-288, 1998.
72. Young R, Jones A, and Nicholls P. Something in the air: endotoxins and glucans as environmental troublemakers. J Pharm Pharmacol 50: 11-17, 1998.
73. Zhiping W, Malmberg P, Larsson B-M, Larsson K, Larsson L, and Saraf A. Exposure to bacteria in swine-house dust and acute inflammatory reactions in humans. Am J Respir Crit Care Med 154: 1261-1266, 1996.