Increased bone turnover is associated with protein and energy metabolism in adolescents with sickle cell anemia

American Journal of Physiology - Endocrinology and Metabolism

Volumn 280, Issue 3 43-3, 2001, Pages

  Buchowski, Maciej S ^a,b,c   De La Fuente, F Alexander ^a   Flakoll, Paul J ^c   Chen, Kong Y ^c   Turner, Ernest A ^b  

^a Healthy Lifestyle and Disease Prevention   (United States)

^b MEHARRY MEDICAL COLLEGE   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bone remodeling; Energy expenditure; Protein turnover; Sickle cell disease

Indexed keywords

GLYCINE; NITROGEN 15; PROCOLLAGEN C PROTEINASE; PYRIDINOLINE;

ADOLESCENT; ADULT; ARTICLE; BONE REMODELING; BONE TURNOVER; CALORIMETRY; CATABOLISM; CLINICAL ARTICLE; DISEASE ASSOCIATION; ENERGY EXPENDITURE; ENERGY METABOLISM; FEMALE; HOMOZYGOSITY; HUMAN; MALE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN METABOLISM; SICKLE CELL ANEMIA; TURNOVER TIME;

EID: 0035006311     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2001.280.3.e518     Document Type: Article

References (39)

1. Adams JG III. Clinical laboratory diagnosis. In: Sickle Cell Disease: Basic Principles and Clinical Practice, edited by Embury SH, Hebbel RP, Mohandas N, and Steinberg MH. Philadelphia, PA: Lippincott-Raven, 1994, p. 457-468.
2. Badaloo A, Jackson AA, and Jahoor F. Whole body protein turnover and resting metabolic rate in homozygous sickle cell disease. Clin Sci (Colch) 77: 93-97, 1989.
3. Barden EM, Zemel BS, Kawchak DA, Goran MI, Obene-Frempong K, and Stallings VA. Total and resting energy expenditure in children with sickle cell disease. J Pediatr 136: 73-79, 2000.
4. Blumsohn A, Hannon RA, Wrate R, Barton J, Al-Dehaimi AW, Colwell A, and Eastell R. Biochemical markers of bone turnover in girls during puberty. Clin Endocrinol (Oxf) 40: 663-670, 1994.
5. Bolarin DM, Swerdlow P, Wallace AM, and Littsey L. Type I collagen as a marker of bone metabolism in sickle cell hemoglobinopathies. J Natl Med Assoc 90: 41-45, 1998.
6. Bollen AM, Martin MD, Leroux BG, and Eyre DR. Circadian variation in urinary excretion of bone collagen cross-links. J Bone Min Res 10: 1885-1890, 1995.
7. Borel MJ, Buchowski MS, Turner EA, Goldstein RE, and Flakoll PJ. Protein turnover and energy expenditure increase during exogenous nutrient availability in sickle cell disease. Am J Clin Nutr 68: 607-614, 1998.
8. Borel MJ, Buchowski MS, Turner EA, Peeler BB, Goldstein RE, and Flakoll PJ. Alterations in basal nutrient metabolism increase resting energy expenditure in sickle cell disease. Am J Physiol Endocrinol Metab 274: E357-E364, 1998.
9. Buchowski MS, Simmons LA, Chen KY, Flakoll PJ, Mellen BG, and Turner EA. Plasma leptin association with body composition and energy expenditure in sickle cell disease. J Am Col Nutr 19: 228-236, 2000.
10. Calvo MS, Eyre DR, and Gundberg CM. Molecular basis and clinical application of biological markers of bone turnover. Endocr Rev 17: 333-368, 1996.
11. Charache S and Page DL. Infarction of bone marrow in the sickle cell disorders. Ann Intern Med 67: 1195-1200, 1967.
12. Christenson RH. Biochemical markers of bone metabolism: an overview. Clin Biochem 30: 573-593, 1997.
13. Diggs LW. Bone and joint lesions in sickle-cell disease. Clin Orthop 52: 119-143, 1967.
14. El-Hazmi MA, Bahakim HM, and al-Fawaz I. Endocrine functions in sickle cell anaemia patients. J Trop Pediatr 38: 307-313, 1995.
15. Embury SH, Hebbel RP, Steinberg MH, and Mohandas N. Pathogenesis of vasoocclusion. In: Sickle Cell Disease: Basic Principles and Clinical Practice, edited by Embury SH, Hebbel RP, Mohandas N, and Steinberg MH. Philadelphia, PA: Lippincott-Raven, 1994, p. 327-334.
16. Glader BE. Anemia. In: Sickle Cell Disease: Basic Principles and Clinical Practice, edited by Embury SH, Hebbel RP, Mohandas N, and Steinberg MH. Philadelphia, PA: Lippincott-Raven, 1994, p. 545-555.
17. Ingram VM. Gene mutations in human haemoglobin: the chemical difference between normal and sickle cell haemoglobin. Nature 180: 326-328, 1957.
18. 15N-glycine and enrichment in urinary ammonia. Hum Nutr Clin Nutr 41: 263-276, 1987.
19. Lipton A, Demers L, Daniloff Y, Curley E, Hamilton C, Harvey H, Witters L, Seaman J, Van der Giessen R, and Seyedin S. Increased urinary excretion of pyridinium cross-links in cancer patients. Clin Chem 39: 614-618, 1993.
20. Luban NL, Leikin SL, and August GA. Growth and development in sickle cell anemia. Preliminary report. Am J Pediatr Hematol Oncol 4: 61-65, 1982.
21. McCurdy PR. DFP and Cr for measurement of red cell life span in abnormal hemoglobin syndromes. Blood 33: 214-224, 1969.
22. Milner PF, Joe C, and Burke GJ. Bone and joint disease. In: Sickle Cell Disease: Basic Principles and Clinical Practice, edited by Embury SH, Hebbel RP, Mohandas N, and Steinburg MH. Philadelphia, PA: Lippincott-Raven, 1996, p. 645-661.
23. Picou D, and Taylor-Roberts T. The measurement of total protein synthesis and catabolism and nitrogen turnover in infants in different nutritional states and receiving different amounts of dietary protein. Clin Sci (Colch) 36: 283-296, 1969.
24. Preedy VR, McNurlan MA, and Garlick PJ. Protein synthesis in skin and bone of the young rat. Br J Nutr 49: 517-523, 1983.
25. Rauch F, Schönau E, Woitge H, Remer T, and Seibel M. Urinary excretion of hydroxy-pyridinium cross-links of collagen reflects skeletal growth velocity in normal children. Exp Clin Endoicrinol 102: 94-97, 1994.
26. Riis BJ, Krabbe S, Christiansen C, Catherwood BD, and Deftos LJ. Bone turnover in male puberty: a longitudinal study. Calcif Tissue Int 37: 213-217, 1985.
27. Risteli J, Niemi S, Kauppila S, Melkko J, and Risteli L. Collagen propeptides as indicators of collagen assembly. Acta Orthop Scand 66, Suppl 266: 183-188, 1995.
28. Robins SP. Collagen crosslinks in metabolic bone disease. Acta Orthop Scand 66, Suppl 266: 171-175, 1995.
29. Rodan GA, Raisz LG, and Bilezikian JP. Pathophysiology of osteoporosis. In: Principles of Bone Biology, edited by Bilezikian JP, Raisz LG, and Rodan GA. San Diego, CA: Academic, 1996, p. 979-990.
30. Rotteveel J, Schoute E, and Delemarre-van de Waal HA. Serum procollagen I carboxyterminal propeptide (PICP) levels through puberty: relation to height velocity and serum hormone levels. Acta Paediatr 86: 143-147, 1997.
31. Salman EK, Haymond MW, and Bayne E. Protein and energy metabolism in prepubertal children with sickle cell anemia. Pediatr Res 40: 34-40, 1996.
32. Serjeant GR. Sickle Cell Disease (2nd ed.). Oxford, UK: Oxford University, 1992.
33. Shaw NJ, Dutton J, Fraser WD, and Smith CS. Urinary pyridinoline and deoxypyridinoline excretion in children. Clin Endocrinol (Oxf) 42: 607-612, 1995.
34. Singhal A, Davies P, Sahota A, Thomas PW, and Serjeant GR. Resting metabolic rate in homozygous sickle cell disease. Am J Clin Nutr 57: 32-34, 1993.
35. Smedsrød B, Melkko J, Risteli L, and Risteli J. Circulating C-terminal propeptide of type I procollagen is cleared mainly via the mannose receptor in liver endothelial cells. Biochem J 271: 345-350, 1990.
36. Sorva R, Anttila R, Siimes MA, Sorva A, Tähtelä R, and Turpeinen M. Serum markers of collagen metabolism and serum osteocalcin in relation to pubertal development in 57 boys at 14 years of age. Pediatr Res 42: 528-532, 1997.
37. 15N]glycine. Am J Physiol Endocrinol Metab 239: E294-E300, 1980.
38. Sun M, Reed GW, and Hill JO. Modification of a whole room indirect calorimeter for measurement of rapid changes in energy expenditure. J Appl Physiol 76: 2686-2691, 1994.
39. 15N: comparison of end products and dose regimes. Am J Physiol Endocrinol Metab Gastrointest Physiol 235: E165-E174, 1978.