Specific prorenin/renin binding (ProBP): Identification and characterization of a novel membrane site

American Journal of Hypertension

Volumn 9, Issue 5, 1996, Pages 491-495

  Sealey, Jean E ^a   Catanzaro, Daniel F ^a   Lavin, Thomas N ^a   Gahnem, Fuad ^a   Pitarresi, Tina ^a   Hu, Lu Fei ^a   Laragh, John H ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Hypertension; Prorenin; Prorenin binding; Protein purification; Radiolabeled prorenin; Rat; Recombinant prorenin; Renin; Renin binding; Tissue directed renin

Indexed keywords

PRORENIN; RENIN; RENIN INHIBITOR; RENIN RECEPTOR; SQ 30697; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HORMONE BINDING; HYPERTENSION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; RAT; TISSUE INTERACTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; LIGANDS; MALE; MEMBRANES; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; RENIN; SULFUR RADIOISOTOPES; THERMODYNAMICS; TISSUE DISTRIBUTION;

EID: 0030014287     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/0895-7061(96)00092-1     Document Type: Article

References (52)

1. Sealey JE, Laragh JH: The renin-angiotensin-aldosterone system for normal regulation of blood pressure and sodium and potassium homeostasis, in Laragh JH, Brenner BM (eds): Hypertension: Pathophysiology, Diagnosis and Management. New York, Raven Press, 1990, pp 1287-1317.
2. Sealey JE, Rubattu S: Prorenin and renin as separate mediators of tissue and circulating systems. Am J Hypertens 1989;2:358-366.
3. Reudelhuber TL, Mercure C, Ramla D, et al: Molecular mechanisms of processing and sorting in renin secretion, in Laragh JH, Brenner BM (eds): Hypertension: Pathophysiology, Diagnosis and Management. New York, Raven Press, 1995, pp 1621-1636.
4. Sealey JE, Quimby FW, Itskovitz J, Rubattu S: The ovarian renin-angiotensin system. Frontiers Neuroendocrinol 1990;11:213-237.
5. Shaw KJ, Do YS, Kjos S, et al: Human decidua is a major source of renin. J Clin Invest 1989;83:2085-2092.
6. Derkx FHM, Schalekamp MADH: Human prorenin: pathophysiology and clinical implications. Clin Exp Hypertens [A] Theor Prac 1988;A10:1213-1225.
7. Kim S, Hosoi M, Nakajima K, Yamamoto K: Immunological evidence that kidney is primary source of circulating inactive prorenin in rats. Am J Physiol 1991; 260:E526-E536.
8. Nielsen AH, Poulsen K: Is prorenin of physiological and clinical significance? J Hypertens 1988;6:949-958.
9. Sealey JE, von Lutterotti N, Campbell WG, Jr., et al: The greater renin system: its prorenin-directed vasodilator limb. Relevance to diabetes mellitus, pregnancy and hypertension. Am J Hypertens 1991;4:972-977.
10. Sealey JE, Glorioso N, Itskovitz J, Laragh JH: Prorenin as a reproductive hormone: a new form of the renin system. Am J Med 1986;81:1041-1046.
11. Skeggs LTJ, Dorer FE: Incorporation of labeled renin into the tissues of the rabbit. Am J Hypertens 1989; 2:768-779.
12. Loudon M, Bing RF, Thurston H, Swales JD: Arterial wall uptake of renal renin and blood pressure control. Hypertension 1983;5:629-634.
13. Gould AB, Skeggs LT, Kahn JR: The presence of renin activity in blood vessel walls. J Exp Med 1964;119:389-399.
14. Thurston H, Swales JD, Bing RF, et al: Vascular renin-like activity and blood pressure maintenance in the rat. Studies of the effect of changes in sodium balance, hypertension and nephrectomy. Hypertension 1979;1: 643-649.
15. Fordis CM, Megorden JS, Ropchak RG, Keiser HR: Absence of renin-like activity in rat aorta and microvessels. Hypertension 1983;5:635-641.
16. Tigerstedt R, Bergman PG: Niere und Kreislauf (in German). Skand Arch Physiol 1898;8:223-271.
17. Admiraal PJJ, Jan Danser AH, Sjoukje Jong M, et al: Regional angiotensin II production in essential hypertension and renal artery stenosis. Hypertension 1993; 21:173-184.
18. Campbell DJ, Valentijn AJ: Identification of vascular renin-binding proteins by chemical cross-linking: inhibition of binding of renin by renin inhibitors. J Hypertens 1994;12:879-890.
19. Wilson DM, Luetscher JA: Plasma prorenin activity and complications in children with insulin-dependent diabetes mellitus. N Engl J Med 1990;323:1101-1106.
20. Halimi J, Sealey JE: Prorenin in diabetes mellitus. Trends Endocrinol Metab 1992;7:270-275.
21. Burnham CE, Hawelu-Johnson CL, Frank BM, Lynch KR: Molecular cloning of rat renin cDNA and its gene. Proc Natl Acad Sci USA 1987;84:5605-5609.
22. Chu WN, Baxter JD, Reudelhuber TL: A targeting sequence for dense secretory granules resides in the active renin protein moiety of human preprorenin. Mol Endocrinol 1990;4:1905-1913.
23. Cockett MI, Bebbington CR, Yarranton GT: High level expression of tissue inhibitor metalloproteinases in Chinese hamster ovary cells using glutamine synthetase gene amplification. Biotechnology 1990;8:662-667.
24. Sealey JE: Plasma renin activity and plasma prorenin assays. Clin Chem 1991;37:1811-1819.
25. Johannessen A, Nielsen AH, Poulsen K: Measurement of inactive renin in rat plasma: effect of nephrectomy and sialoadenectomy on the plasma concentration. J Hypertens 1990;8:345-349.
26. Campbell WG, Jr., Gahnem F, Catanzaro DF, et al: Plasma and renin prorenin/renin, renin mRNA and blood pressure in Dahl S and R rats. Hypertension 1996;27:1121-1133.
27. Chang JJ, Kisaragi M, Okamoto H, Inagami T: Isolation and activation of inactive renin from human kidney and plasma. Plasma and renal inactive renins have different molecular weights. Hypertension 1981;3:509-519.
28. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the folin phenol reagent. J Biol Chem 1951;193:265-270.
29. Kent RS, DeLean A, Lefkowitz RJ: Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. Mol Pharmacol 1982;21:5-16.
30. Lavin TN, Hoffman BB, Lefkowitz RJ: Determination of subtype selectivity of alpha adrenergic antagonists. Mol Pharmacol 1981;20:28-34.
31. Heinrikson RL, Hui J, Zurcher-Neely H, Poorman RA: A structural model to explain the partial catalytic activity of human prorenin. Am J Hypertens 1989;2:367-380.
32. Bouhnik J, Clauser E, Strosberg D, et al: Rat angiotensinogen and des(angiotensin I)angiotensinogen: purification, characterization, and partial sequencing. Biochemistry 1981;20:7010-7015.
33. Pitarresi T, Rubattu S, Heinrikson RL, Sealey JE: Reversible cryoactivation of recombinant human prorenin. J Biol Chem 1992;267:11753-11759.
34. Hull CJ: Pharmacokinetics and pharmacodynamics. Br J Anaesth 1979;51:579-594.
35. Hiruma M, Kim S, Ikemoto F, et al: Fate of recombinant human renin administered exogenously to anesthetized monkeys. Hypertension 1988;12:317-323.
36. Aeed PA, Guido DM, Mathews WR, Elhammer AP: Characterization of the oligosaccharide structures on recombinant human prorenin expressed in Chinese hamster ovary cells. Biochemistry 1992;31:6951-6961.
37. Katz SA, Malvin RL: Isoelectric heterogeneity of secreted renin differs after beta-adrenergic blockade. Endocrinology 1982;111:814-819.
38. Kim S, Hosoi M, Kikuchi N, Yamamoto K: Amino-terminal amino acid sequence and heterogeneity in glycosylation of rat renal renin. J Biol Chem 1991;266:7044-7050.
39. Cohen S, Taylor JM, Murakami K, et al: Isolation and characterization of renin-like enzymes from mouse submaxillary glands. Biochemistry 1972;11:4286-4293.
40. Kim S, Hiruma M, Ikemoto F, Yamamoto K: Importance of glycosylation for hepatic clearance of renal renin. Am J Physiol 1988;255:E642-E651.
41. Wood JM, Levens NR: Intrarenal blockade of angiotensin II in experimental genetic hypertension, in Laragh JH, Brenner BM (eds): Hypertension: Pathophysiology, Diagnosis, and Management. New York, Raven Press, 1995, pp 1477-1488.
42. Lenz T, Sealey JE, Maack T, et al: Half-life, hemodynamic, renal and hormonal effects of prorenin in cynomolgus monkeys. Am J Physiol 1991;29:R804-R810.
43. von Lutterotti N, Gulmi FA, Marion D, et al: Increased plasma prorenin but not renin after bilateral ureteral ligation in dogs. Kidney Int 1991;39:901-906.
44. Naruse M, Takii Y, Inagami T: Renin exists in high concentration in the adrenal gland of the rat. Biomed Res 1981;2:583-586.
45. Sander M, Bader M, Djavidani B, et al: The role of the adrenal gland in hypertensive transgenic rat TGR(mREN2)27. Endocrinology 1992;131:807-814.
46. Seikaly MG, Arant BSJ, Seney FD, Jr.: Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat. J Clin Invest 1990; 86:1352-1357.
47. Braam B, Mitchell KD, Fox J, Navar LG: Proximal tubular secretion of angiotensin II in rats. Am J Physiol 1993;264:F891-F898.
48. Takahashi S, Ohsawa T, Miura R, Miyake Y: Purification of high molecular weight (HMW) renin from porcine kidney and direct evidence that the HMW renin is a complex of renin with renin binding protein (RnBP). J Biochem (Tokyo) 1983;93:265-274.
49. Murakami K, Chino S, Hirose S, Higaki J: Specificity and localization of renin-binding protein(s). Biomed Res 1980;1:476-481.
50. Tada M, Takahashi S, Miyano M, Miyake Y: Tissue-specific regulation of renin-binding protein gene expression in rats. J Biochem (Tokyo) 1992;112:175-182.
51. Hein L, Ishii K, Coughlin SR: Intracellular targeting and trafficking of thrombin receptors. A novel mechanism for resensitization of a G protein-coupled receptor. J Biol Chem 1994;269:27719-27726.
52. Hajjar K, Jacovina AT, Chacko J: An endothelial cell receptor for plasminogen-tissue plasminogen activator: identity with annexin II. J Biol Chem 1994;269:21191-21197.