Correlation of clinicopathological parameters and biological markers related to apoptosis and proliferative activity with a clinical outcome in squamous cell carcinoma of the larynx treated with concurrent chemoradiotherapy

Auris Nasus Larynx

Volumn 28, Issue SUPPL., 2001, Pages

  Homma, A ^a   Furuta, Y ^a   Oridate, N ^a   Nakano, Y ^a   Yagi, K ^a   Nagahashi, T ^a   Fukuda, S ^a   Inuyama, Y ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Bax; bcl 2; Chemoradiotherapy; Laryngeal cancer; MIB 1; p53; Proliferative activity

Indexed keywords

BIOLOGICAL FACTOR; CARBOPLATIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CELL PROLIFERATION; CLINICAL FEATURE; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LARYNX CARCINOMA; MAJOR CLINICAL STUDY; MALE; OUTCOMES RESEARCH; SQUAMOUS CELL CARCINOMA;

APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; COMBINED MODALITY THERAPY; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LARYNGEAL NEOPLASMS; MALE; MIDDLE AGED; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 0035003104     PISSN: 03858146     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0385-8146(01)00067-0     Document Type: Article

References (27)

1. A phase II study of concomitant chemoradiotherapy for laryngeal carcinoma using carboplatin
2. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
3. bcl-2 protein expression correlates with recurrence and survival in early stage head and neck cancer treated by radiotherapy
4. Predictive and prognostic markers in a series of patients with head and neck squamous cell invasive carcinoma treated with concurrent chemoradiation therapy
5. Bcl-2 expression correlates with favourable outcome in head and neck cancer treated by accelerated radiotherapy
6. Bcl-xL and Bcl-2 expression in squamous cell carcinoma of the head and neck
7. p53 expressions: predicting recurrence and second primary tumors in head and neck squamous cell carcinoma
8. The Department of Veterans Affairs Laryngeal Cancer Study Group. Overexpression of p53 predicts organ preservation using induction chemotherapy and radiation in patients with advanced laryngeal cancer
9. p53 mutation as a prognostic marker in advanced laryngeal carcinoma. Department of Veterans Affairs Laryngeal Cancer Cooperative Study Group
10. Bcl-2 but not Bax expression is associated with apoptosis in normal and transformed squamous epithelium
11. Spontaneous apoptosis in laryngeal squamous cell carcinoma is independent of bcl-2 and bax protein expression
12. Spontaneous apoptosis and the expression of p53 and Bcl-2 family proteins in locally advanced head and neck cancer
13. Cell proliferation kinetics in human solid tumors: relation to probability of metasatatic dissemination and long-term survival
14. Prognostic significance of cell kinetics in laryngeal squamous cell carcinoma: clinicopathological associations
15. Has the cellular proliferation marker Ki67 any clinical relevance in squamous cell carcinoma of the head and neck?
16. Correlation of tumor markers p53, bcl-2, CD34, CD44H, CD44v6, and Ki-67 with survival and metastasis in laryngeal squamous cell carcinoma
17. Squamous-cell epithelioma of the lip. A study of five hundred and thirty-seven cases
18. Carcinoma and other tumors of the cervix
19. Prognostic significance of clinical parameters and biological markers in patients with squamous cell carcinoma of the head and neck treated with concurrent chemoradiotherapy
20. The bcl-2 protein: a prognostic indicator strongly related to p53 protein in lymph node-negative breast cancer patients
21. Lymph node prognostic factors in head and neck squamous cell carcinomas
22. Head and neck cancer
23. bcl-2 protein in non-small-cell lung carcinoma
24. Bcl-2 protein: a prognostic factor inversely correlated to p53 in non-small-cell lung cancer
25. p53 point mutation and survival in colorectal cancer patients
26. Bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death