Transcriptional regulation of the ovine follicle-stimulating hormone-β gene by activin and gonadotropin-releasing hormone (GnRH): Involvement of two proximal activator protein-1 sites for GnRH stimulation

Endocrinology

Volumn 142, Issue 6, 2001, Pages 2267-2274

  Huang, Huey Jing ^a   Sebastian, Joseph ^a,b   Strahl, Brian D ^a,c   Wu, Joyce C ^a   Miller, William L ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b LABORATORY CORPORATION OF AMERICA   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; FOLLISTATIN; FOLLITROPIN; GONADORELIN; LUCIFERASE; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE INDUCTION; GENE MUTATION; GENETIC TRANSCRIPTION; HORMONAL REGULATION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; TRANSGENE; TRANSGENIC MOUSE;

EID: 0035000864     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.142.6.8203     Document Type: Article

References (26)

1. 1. Carroll RS, Kowash PM, Lofgren JA, Schwall RH, Chin WW 1991 In vivo regulation of FSH synthesis by inhibin and activin. Endocrinology 129:3299-3304
2. 2. Weiss J, Harris PE, Halvorson LM, Crowley Jr WF, Jameson JL 1992 Dynamic regulation of follicle-stimulating hormone-β messenger ribonucleic acid levels by activin and gonadotropin-releasing hormone in perifused rat pituitary cells. Endocrinology 131:1403-1408
3. 3. Weiss J, Guendner MJ, Halvorson LM, Jameson JL 1995 Transcriptional activation of the follicle-stimulating hormone β-subunit gene by activin. Endocrinology 136:1885-1891
4. 4. Gaddy-Kurten D, Tsuchida K, Vale W 1995 Activins and the receptor serine kinase superfamily. Recent Prog Horm Res 50:109-129
5. B subunits in various tissues predicts diverse functions. Proc Natl Acad Sci USA 85:247-251
6. 6. Roberts V, Meunier H, Vaughan J, Rivier J, Rivier C, Vale W, Sawchenko P 1989 Production and regulation of inhibin subunits in pituitary gonadotropes. Endocrinology 124:552-554
7. 7. Corrigan AZ, Bilezikjian LM, Carroll RS, Bald LN, Schmelzer CH, Fendly BM, Mason AJ, Chin WW, Schwall RH, Vale W 1991 Evidence for an autocrine role of activin B within rat anterior pituitary cultures. Endocrinology 128:1682-1684
8. 8. Wierman ME, Rivier JE, Wang C 1989 Gonadotropin-releasing hormone-dependent regulation of gonadotropin subunit messenger ribonucleic acid levels in the rat. Endocrinology 124:272-278
9. 9. Haisenleder DJ, Dalkin AC, Ortolano GA, Marshall JC, Shupnik MA 1991 A pulsatile gonadotropin-releasing hormone stimulus is required to increase transcription of the gonadotropin subunit genes: evidence for differential regulation of transcription by pulse frequency in vivo. Endocrinology 128:509-517
10. 2+ and protein kinase C. Front Neuroendocrinol 19:1-19
11. 11. Sundaresan S, Colin IM, Pestell RG, Jameson JL 1996 Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone: evidence for the involvement of protein kinase C. Endocrinology 137:304-311
12. 12. Haisenleder DJ, Cox ME, Parsons SJ, Marshall JC 1998 Gonadotropin-releasing hormone pulses are required to maintain activation of mitogen-activated protein kinase: role in stimulation of gonadotrope gene expression. Endocrinology 139:3104-3111
13. 13. Strahl BD, Huang HJ, Pedersen NR, Wu JC, Ghosh BR, Miller WL 1997 Two proximal activating protein-1-binding sites are sufficient to stimulate transcription of the ovine follicle-stimulating hormone-β gene. Endocrinology 138:2621-2631
14. 14. Strahl BD, Huang HJ, Sebastian J, Ghosh BR, Miller WL 1998 Transcriptional activation of the ovine follicle-stimulating hormone beta-subunit gene by gonadotropin-releasing hormone: involvement of two activating protein-1-binding sites and protein kinase C. Endocrinology 139:4455-4465
15. 14a. Huang HJ, Sebastian J, Strahl BD, Wu JC, Miller WL 2001 The promoter for the ovine follicle-stimulating hormone-β gene (FSHβ) confers FSHβ-like expression on luciferase in transgenic mice: regulatory studies in vivo and in vitro. Endocrinology 142:2260-2226
16. 15. Esbenshade KL, Vogel MJ, Traywick GB 1986 Clearance rate of luteinizing hormone and follicle stimulating hormone from peripheral circulation in the pig. J Anim Sci 62:1649-1653
17. 16. de Winter JP, ten Dijke P, de Vries CJ, van Achterberg TA, Sugino H, de Waele P, Huylebroeck D, Verschueren K, van den Eijnden-van Raaij AJ 1996 Follistatins neutralize activin bioactivity by inhibition of activin binding to its type II receptors. Mol Cell Endocrinol 116:105-114
18. 17. Miller CD, Miller WL 1996 Transcriptional repression of the ovine follicle-stimulating hormone-β gene by 17β-estradiol. Endocrinology 137:3437-3446
19. 18. Webster JC, Pedersen NR, Edwards DP, Beck CA, Miller WL 1995 The 5′-flanking region of the ovine follicle-stimulating hormone-β gene contains six progesterone response elements: three proximal elements are sufficient to increase transcription in the presence of progesterone. Endocrinology 136:1049-1058
20. 19. Graham KE, Nusser KD, Low MJ 1999 LβT2 gonadotroph cells secrete follicle stimulating hormone (FSH) in response to active A. J Endocrinol 162:R1-R5
21. 19a. Pernasetti F, Vasilyev VV, Rosenberg SB, Bailey JS, Huang H-J, Miller WL, Mellon PL 2001 Cell-specific transcriptional regulation of follicle-stimulating hormone-β by activin and gonadotropin-releasing hormone in LβT2 pituitary gonadotrope cell model. Endocrinology 142:2284-2295
22. 20. Besecke LM, Guendner MJ, Schneyer AL, Bauer-Dantoin AC, Jameson JL, Weiss J 1996 Gonadotropin-releasmg hormone regulates follicle-stimulating hormone-β gene expression through an activin/follistatin autocrine or paracrine loop. Endocrinology 137:3667-3673
23. 21. Fernandez-Vazquez G, Kaiser UB, Albarracin CT, Chin WW 1996 Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A. Mol Endocrinol 10:356-366
24. 22. Braden TD, Conn PM 1992 Activin-A stimulates the synthesis of gonadotropin-releasing hormone receptors. Endocrinology 130:2101-2105
25. 23. Bilezikjian LM, Corrigan AZ, Vaughan JM, Vale WM 1993 Activin-A regulates follistatin secretion from cultured rat anterior pituitary cells. Endocrinology 133:2554-2560
26. 24. Culler MD, Negro-Vilar A 1986 Evidence that pulsatile follicle-stimulating hormone secretion is independent of endogenous luteinizing hormone-releasing hormone. Endocrinology 118:609-612