A quantitative analysis of the glomerular charge barrier in the rat

American Journal of Physiology - Renal Physiology

Volumn 280, Issue 4 49-4, 2001, Pages

  Sörensson, Jenny ^a   Ohlson, Maria ^a   Haraldsson, Börje ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Capillary permeability; Charge; Endothelium; Kidney glomerulus physiology

Indexed keywords

ALBUMIN; FICOLL; FLUORESCEIN ISOTHIOCYANATE; HORSERADISH PEROXIDASE; IODINE 125; OROSOMUCOID; OVALBUMIN;

ANIMAL TISSUE; ARTICLE; CAPILLARY PERMEABILITY; ENDOTHELIUM; ENZYME ACTIVITY; FEMALE; GLOMERULUS; GLOMERULUS FILTRATION RATE; IONIC STRENGTH; ISOLATED KIDNEY; ISOTOPE LABELING; KIDNEY PERFUSION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0034998158     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.2001.280.4.f646     Document Type: Article

References (52)

1. Anderson JL and Malone DM. Mechanism of osmotic flow in porous membranes. Biophys J 14: 957-982, 1974.
2. Bohrer MP, Baylis C, Humes HD, Glassock RJ, Robertson CR, and Brenner BM. Permselectivity of the glomerular capillary wall. Facilitated filtration of circulating polycations. J Clin Invest 61: 72-78, 1978.
3. Bolton GR, Deen WM, and Daniels BS. Assessment of the charge selectivity of glomerular basement membrane using Ficoll sulfate. Am J Physiol Renal Physiol 274: F889-F896, 1998.
4. Cecil R and Ogston AG. Determination of sedimentation and diffusion constants of horseradish peroxidase. Biochem J 49: 105-106, 1951.
5. Chang RL, Ueki IF, Troy JL, Deen WM, Robertson CR, and Brenner BM. Permselectivity of the glomerular capillary wall to macromolecules. II. Experimental studies in rats using neutral dextran. Biophys J 15: 887-906, 1975.
6. +K)-ATPase. Arch Biochem Biophys 142: 633-637, 1971.
7. Ciarimboli G, Schurek H-J, Zeh M, Flohr H, Bökenkamp A, Fels LM, Kilian I, and Stolte H. Role of albumin and glomerular capillary wall charge distribution on glomerular permselectivity: studies on the perfused-fixed rat kidney model. Pflügers Arch 438: 883-891, 1999.
8. Comper WD and Glasgow EF. Charge selectivity in kidney ultrafiltration. Kidney Int 47: 1242-1251, 1995.
9. Curry FE and Michel CC. A fiber matrix model of capillary permeability. Microvasc Res 20: 96-99, 1980.
10. Deen WM, Satvat B, and Jamieson JM. Theoretical model for glomerular filtration of charged solutes. Am J Physiol Renal Fluid Electrolyte Physiol 238: F126-F139, 1980.
11. Esmann M and Skou JC. Temperature-dependencies of various catalytic activities of membrane-bound Na/K-ATPase from ox brain, ox kidney and shark rectal gland and of C12E8-solubilized shark Na/K-ATPase. Biochim Biophys Acta 944: 344-350, 1988.
12. Florkin E and Stotz H. (Editors). Proteins Comprehensive Biochemistry. Amsterdam: Elsevier Scientific, 1963, vol. 7, p. 50.
13. Guasch A, Deen WM, and Myers BD. Charge selectivity of the glomerular filtration barrier in healthy and nephrotic humans. J Clin Invest 92: 2274-2282, 1993.
14. Hanley MJ and Davidson K. Prior mannitol and furosemide infusion in a model of ischemic acute renal failure. Am J Physiol Renal Fluid Electrolyte Physiol 241: F556-F564, 1981.
15. Haraldsson BS, Johnsson EK, and Rippe B. Glomerular permselectivity is dependent on adequate serum concentrations of orosomucoid. Kidney Int 41: 310-316, 1992.
16. Haraldsson G, Sorensen V, Nilsson U, Pettersson S, Rashid M, Schersten T, Akerlund S, and Jonsson O. Effect of pretreatment with desferrioxamine and mannitol on radical production and kidney function after ischaemia-reperfusion. A study on rabbit kidneys. Acta Physiol Scand 154: 461-468, 1995.
17. Johnson EM and Deen WM. Electrostatic effects on the equilibrium partitioning of spherical colloids in random fibrous media. J Colloid Interface Sci 178: 749-756, 1996. (Corrigenda. J Colloid Interface Sci 195: 268, 1997, p. 000.)
18. Johnsson E and Haraldsson B. An isolated perfused rat kidney preparation designed for assessment of glomerular permeability characteristics. Acta Physiol Scand 144: 65-73, 1992.
19. Johnston ST and Deen WM. Hindered convection of proteins in agarose gels. J Membr Sci 153: 271-279, 1999.
20. Kanwar YS and Rosenzweig LJ. Clogging of the glomerular basement membrane. J Cell Biol 93: 489-493, 1982.
21. Kawahara K, Ikenaka T, Nimberg RB, and Schmid K. The effect of the sialyl residues on the thermodynamic and hydrodynamic properties of alphal-acid glycoprotein. Biochim Biophys Acta 295: 505, 1973.
22. Kerjaschki D, Sharkey DJ, and Farquhar MG. Identification and characterization of podocalyxin - the major sialoprotein of the renal glomerular epithelial cell. J Cell Biol 98: 1591-1596, 1984.
23. Kestila M, Lenkkeri U, Mannikko M, Lamerdin J, McCready P, Putaala H, Ruotsalainen V, Morita T, Nissinen M, Herva R, Kashtan CE, Peltonen L, Holmberg C, Olsen A, and Tryggvason K. Positionally cloned gene for a novel glomerular protein - nephrin - is mutated in congenital nephrotic syndrome. Mol Cell 1: 575-582, 1998.
24. Klotz IM. Succinylation. In: Methods in Enzymology, edited by Hirs CHW. New York: Academic, 1979, vol. 11, p. 576-580.
25. Lamm O and Poison A. Biochem J 30: 528-531, 1936.
26. Lindström K, Blom A, Johnsson E, Haraldsson B, and Fries E. High glomerular permeability of bikunin despite similarity in charge and hydrodynamic size to serum albumin. Kidney Int 51: 1053-1058, 1997.
27. Lindström KE, Johnsson E, and Haraldsson B. Glomerular charge selectivity for proteins larger than serum albumin as revealed by lactate dehydrogenase isoforms. Acta Physiol Scand 162: 481-488, 1998.
28. Luft JH. Fine structure of capillary and endocapillary layer as revealed by ruthenium red. Federation Proc 25: 1773-1783, 1966.
29. Munch WD, Zestar LP, and Anderson JL. Rejection of polyelectrolytes from microporous membranes. J Membr Sci 5: 77-102, 1979.
30. Nielsen S. Sorting and recycling efficiency of apical insulin binding sites during endocytosis in proximal tubule cells. Am J Physiol Cell Physiol 264: C810-C822, 1993.
31. Ogston AG. The space in a uniform random suspension of fibres. Trans Faraday Soc 54: 1754-1757, 1958.
32. Ohlson M, Sörensson J, and Haraldsson B. Glomerular size and charge selectivity in the rat as revealed by FITC-Ficoll and albumin. Am J Physiol Renal Physiol 279: F84-F91, 2000.
33. Ohlson M, Sörensson J, Lindström K, Blom AM, Fries E, and Haraldsson B. Effects of filtration rate on the glomerular barrier and on the clearance of four differently shaped molecules. Am J Physiol Renal Physiol In press.
34. Ohlson M, Sörensson J, and Haraldsson B. An integrative gel-membrane model of glomerular charge and size selectivity in series. Am J Physiol Renal Physiol 280: F396-F405, 2001.
35. Ojteg G, Nygren K, and Wolgast M. Permeability of renal capillaries. I. Preparation of neutral and charged protein probes. Acta Physiol Scand 129: 277-286, 1987.
36. Oliver JD III, Anderson S, Troy JL, Brenner BM, and Deen WH. Determination of glomerular size-selectivity in the normal rat with Ficoll. J Am Soc Nephrol 3: 214-228, 1992.
37. Osicka TM and Comper WD. Tubular inhibition destroys charge selectivity for anionic and neutral horseradish peroxidase. Biochim Biophys Acta 1381: 170-178, 1998.
38. Osicka TM, Pratt LM, and Comper WD. Glomerular capillary wall permeability to albumin and horseradish peroxidase. Nephrology 2: 199-212, 1996.
39. Pedersen KO. Ultracentrifugal Studies on Serum and Serum . Fractions (PhD thesis). Uppsala University, Uppsala, Sweden: 1945, p. 148.
40. Rennke HG, Patel Y, and Venkatachalam MA. Glomerular filtration of proteins: clearance of anionic, neutral, and cationic horseradish peroxidase in the rat. Kidney Int 13: 324-328, 1977.
41. Rennke HG and Venkatachalam MA. Chemical modification of horseradish peroxidase. J Histochem Cytochem 27: 1352-1353, 1979.
42. Rippe B and Haraldsson B. Transport of macromolecules across microvascular walls: the two-pore theory. Physiol Rev 74: 163-219, 1994.
43. Rippe B, Kamiya A, and Folkow B. Transcapillary passage of albumin, effects of tissue cooling and of increases in filtration and plasma colloid osmotic pressure. Acta Physiol Scand 105-171-187, 1979.
44. Rostgaard J and Qvortrup K. Electron microscopic demonstrations of filamentous molecular sieve plugs in capillary fenestrae. Microvasc Res 53: 1-13, 1997.
45. Ruotsalainen V, Ljungberg P, Wartiovaara J, Lenkkeri U, Kestila M, Jalanko H, Holmberg C, and Tryggvason K. Nephrin is specifically located at the slit diaphragm of glomerular podocytes. Proc Natl Acad Sci USA 96: 7962-7967, 1999.
46. Simionescu M, Simionescu N, Silbert JE, and Palade GE. Differentiated microdomains on the luminal surface of the capillary endothelium. II. Partial characterization of their anionic sites. J Cell Biol 90: 614-621, 1981.
47. Sörensson J, Lindström K, Ohlson M, and Haraldsson B. Evidence for a reversible increase of the glomerular charge selectivity during perfusion with low ionic strengths (Abstract). J Am Soc Nephrol 7: 1589, 1996.
48. Sörensson J, Ohlson M, Lindström K, and Haraldsson B. Glomerular charge selectivity for horseradish peroxidase and albumin at low and normal ionic strengths. Acta Physiol Scand 163: 83-91, 1998.
49. Thean ET. Comparison of specific radioactivities of human alpha-lactalalbumin iodinated by three different methods. Anal Biochem 188: 330-334, 1990.
50. Turner MR, Clough G, and Michel CC. The effects of cationised ferritin and native ferritin upon the filtration coefficient of single frog capillaries. Evidence that proteins in the endothelial cell coat influence permeability. Microvasc Res 25: 205-222, 1983.
51. Wolgast M, Källskog Ö, and Wahlström H. Characteristics of the glomerular capillary membrane of the rat kidney as a hydrated gel. I. Hypothetical structure. Acta Physiol Scand 158: 213-224, 1996.
52. Wolgast M, Källskog Ö, and Wahlström H. Characteristics of the glomerular capillary membrane of the rat kidney as a hydrated gel. II. On the validity of the model. Acta Physiol Scand 158: 225-232, 1996.