Glomerular charge selectivity for proteins larger than serum albumin as revealed by lactate dehydrogenase isoforms

Acta Physiologica Scandinavica

Volumn 162, Issue 4, 1998, Pages 481-488

  Lindstrom K E ^a   Johnsson, E ^a   Haraldsson, B ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Capillary permeability; Charge; Kidney glomerulus physiology; Lactate dehydrogenase; Pore size; Rat

Indexed keywords

ALBUMIN; ISOENZYME; LACTATE DEHYDROGENASE;

ANIMAL TISSUE; ARTICLE; CAPILLARY PERMEABILITY; CONTROLLED STUDY; GLOMERULUS CAPILLARY; GLOMERULUS FILTRATION RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOTOPE LABELING; MALE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; REGIONAL PERFUSION; SURFACE CHARGE; TECHNIQUE; URINALYSIS;

ALBUMINS; ANIMALS; CAPILLARY PERMEABILITY; CELL MEMBRANE PERMEABILITY; GLOMERULAR FILTRATION RATE; ISOENZYMES; KIDNEY GLOMERULUS; L-LACTATE DEHYDROGENASE; MALE; PERFUSION; POROSITY; RATS; RATS, WISTAR;

EID: 0031967845     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1998.0316f.x     Document Type: Article

References (57)

1. Areekul, S. 1969. Reflection coefficients of neutral and sulphate-substituted dextran molecules in the isolated perfused rabbit ear. Acta Soc Med Upsal 74, 129-138.
2. Barnes, J.L., Radnik, R.A., Gilchrist, E.P. & Venkatachalam, M.A. 1984. Size and charge selective permeability defects induced in glomerular basement membrane by a polycation. Kidney Int 25, 11-19.
3. Blouch, K., Deen, W.M., Fauvel, J.P., Bialek, J., Derby, G. & Myers, B.D. 1996. Molecular configuration and glomerular size-selectivity in healthy and nephrotic humans. J Am Soc Nephrol 7, 1329.
4. Bohrer, M.P., Baylis, C., Humes, H.D., Glassock, R.J., Robertson, C.R. & Brenner, B.M. 1978. Permselectivity of the glomerular capillary wall. Facilitated filtration of circulating polycations. J Clin Invest 61, 72-78.
5. Bohrer, M.P., Deen, W.M., Robertson, C.R., Troy, J.L. & Brenner, B.M. 1979. Influence of molecular configuration on the passage of macromolecules across the glomerular capillary wall. J Gen Physiol 74, 583-593.
6. Brenner, B.M., Hostetter, T.H. & Humes, H.D. 1978. Glomerular permselectivity: barrier function based on discrimination of molecular size and charge. Am J Physiol 234, F455-F460.
7. Bridges, C.R., Myers, B.D., Brenner, B.M. & Deen, W.M. 1982. Glomerular charge alterations in human minimal change nephropathy. Kidney Int 22, 677-684.
8. Chang, R.L.S., Deen, W.M., Robertson, C.R. & Brenner, B.M. 1975. Permselectivity of the glomerular capillary wall: III. Restricted transport polyanions Kidney Int 8, 212-218.
9. Charnock, J.S., Doty, D.M. & Russell, J.C. 1971. The effect of temperature on the activity of (Na+K)-ATPase. Arch Biochem Biophys 142, 633-637.
10. Christensen, E.I., Rennke, H.G. & Carone, F.A. 1983. Renal tubular uptake of protein: effect of molecular charge. Am J Physiol 244, F436-F441.
11. Comper, W.D. & Glasgow, E.F. 1995. Charge selectivity in kidney ultrafiltration. Kidney Int 47, 1242-1251.
12. Comper, W.D., Lee, A.S.N., Tay, M. & Adal, Y. 1993. Anionic charge concentration of rat kidney glomeruli and glomerular basement membrane. Biochem J 289, 647-652.
13. Curry, F.E. & Michel, C.C. 1980. A fiber matrix model of capillary permeability. Microvasc Res 20, 96-99.
14. Deen, W.M., Bohrer, M.P. & Brenner, B.M. 1979. Macromolecule transport across glomerular capillaries: application of pore theory. Kidney Int 16, 353-365.
15. Deen, W.M., Bohrer, M.P., Robertson, C.R. & Brenner, B.M. 1977. Determinants of the transglomerular passage of macromolecules. Fed Proc 36, 2614-2618.
16. Deen, W.M., Bridges, C.R., Brenner, B.M. & Myers, B.D. 1985. Heteroporous model of glomerular size selectivity: application to normal and nephrotic humans. Am J Physiol 249, F374-F389.
17. Deen, W.M., Satvat, B. & Jamieson, J.M. 1980. Theoretical model for glomerular filtration of charged solutes. Am J Physiol 238, F126-F139.
18. Di Mario, U., Cancelli, A., Pietravalle, P., Altamore, G., Mariani, G., De Rossi, M.G. et al. 1990. Anionic vs. cationic immunoglobulin clearance in normal subjects: a novel approach to the evalutation of charge permselectivity. Nephron 55, 400-407.
19. 8-solubilized shark Na/K-ATPase. Biochem Biophys Acta 944, 344-350.
20. Farquhar, M.G., Lemkin, M.C. & Stow, J.L. 1984. Role of proteoglycans in glomerular function and pathology. In: R.R. Robinson (ed.) Nephrology, pp. 580-600. Springer Verlag, New York, NY.
21. Fogh-Andersen, N., Bjerrum, P.J. & Siggaard-Andersen, O. 1993. Ionic binding, net charge, and Donnan effect of human serum albumin as a function of pH. Clin Chem 39, 48-52.
22. Guasch, A., Deen, W.M. & Myers, B.D. 1993. Charge selectivity of the glomerular nitration barrier in healthy and nephrotic humans. J Clin Invest 92, 2274-2282.
23. Haraldsson, B. 1986. Physiological studies of macromolecular transport across capillary walls. Studies on continuous capillaries in rat skeletal muscle. Acta Physiol Scand 128 (Suppl. 553), 1-40.
24. Haraldsson, B., Ekholm, C. & Rippe, B. 1983. Importance of molecular charge for the passage of endogenous macromolecules across continuous capillary walls, studied by serum clearance of lactate dehydrogenase (LDH) isoenzymes. Acta Physiol Scand 117, 123-130.
25. Haraldsson, B.S., Johnsson, E.K. & Rippe, B. 1992. Glomerular permselectivity is dependent on adequate serum concentrations of orosomucoid. Kidney Int 41, 310-316.
26. Heyman, S.N., Rosen, S., Epstein, F.H., Spokes, K. & Brezis, M.L. 1994. Loop diuretics reduce hypoxic damage to proximal tubules of isolated perfused rat kidney. Kidney int 45, 981-985.
27. Holbrook, J.J., Liljas, A., Steindal, S.J. & Rossman, M.G. 1975. Lactate dehydrogenase. In: P.D. Boyer (ed.) The Enzymes, pp. 191-292. Academic Press, New York.
28. Johnsson, E. & Haraldsson, B. 1992. An isolated perfused rat kidney preparation designed for assessment of glomerular permeability characteristics. Acta Physiol Scand 144, 65-73.
29. Kitano, Y., Yoshikawa, N. & Nakamura, H. 1993. Glomerular anionic sites in minimal change nephrotic syndrome and focal segmental glomerulosclerosis. Clin Nephrol 40, 199-204.
30. Koopman, M.G., Koomen, G.C.M., van Acker, B.A.C. & Arisz, L. 1996. Circadian rhythm in glomerular transport of macromolecules through large pores and shunt pathway. Kidney Int 49, 1242-1249.
31. Lindström, K.E., Blom, A., Johnsson, E., Haraldsson, B. & Fries, E. 1997. High glomerular permeability of bikunin despite similarity in charge and hydrodynamic size to serum albumin. Kidney Int 51, 1053-1058.
32. Long, T.D. & Anderson, J.L. 1984. Flow-dependent rejection of polystyrene from microporous membranes. J Polym Sci [Polym Phys Ed] 22, 1261-1281.
33. Munch, W.D., Zestar, L.P. & Anderson, J.L. 1979. Rejection of polyelectrolytes from microporous membranes. J Membr Sci 5, 77-102.
34. Myers, B.D. & Guasch, A. 1993. Selectivity of the glomerular filtration barrier in healthy and nephrotic humans. Am J Nephrol 13, 311-317.
35. Nielsen, S. 1993. Sorting and recycling efficiency of apical insulin binding sites during endocytosis in proximal tubule cells. Am J Physiol 264, C810-C822.
36. Öjteg, G., Nygren, K. & Wolgast, M. 1987a. Permeability of renal capillaries. II. Transport of neutral and charged protein molecular probes. Acta Physiol Scand 129, 287-294.
37. Öjteg, G., Nygren, K. & Wolgast, M. 1987b. Permeability of renal capillaries. I. Preparation of neutral and charged protein probes. Acta Physiol Scand 129, 277-286.
38. Öjteg, G. & Wolgast, M. 1993. Charge density of renal interstitium. Acta Physiol Scand 147, 297-303.
39. Oliver, J.D. III., Anderson, S., Troy, J.L., Brenner, B.M. & Deen, W.H. 1992. Determination of glomerular size-selectivity in the normal rat with Ficoll. J Am Soc Nephrol 3, 214-228.
40. Osicka, T.M. & Comper, W.D. 1995. Glomerular charge selectivity for anionic and neutral horseradish peroxidase. Kidney Int 47, 1630-1637.
41. Osicka, T.M., Pratt, L.M. & Comper, W.D. 1996. Glomerular capillary wall permeability to albumin and horseradish peroxidase. Nephrol 2, 199-212.
42. Peters, T. 1985. Serum albumin. Adv Protein Chem 37, 161-245.
43. Renkin, E.M. & Gilmore, J.P. 1973. Glomerular filtration. In: J. Orloff, R.W. Berliner & S.R. Geiger (eds) Handbook of Physiology, Renal Physiology, pp. 185-248. Am Phys Soc, Waverly Press, Washington.
44. Rennke, H.G., Patel, Y. & Venkatachalam, M.A. 1978. Glomerular filtration of proteins: Clearance of anionic, neutral, and cationic horseradish peroxidase in the rat. Kidney Int 13, 324-328.
45. Rennke, H.G. & Venkatachalam, M.A. 1979. Glomerular permeability of macromolecules: Effect of molecular configuration on the fractional clearance of uncharged dextran and neutral horseradish peroxidase in the rat. J Clin Invest 63, 713-717.
46. Rippe, B. & Folkow, B. 1977. Capillary permeability to albumin in normotensive and spontaneously hypertensive rats. Acta Physiol Scand 101, 72-83.
47. Rippe, B. & Haraldsson, B. 1994. Transport of macromolecules across microvascular walls: the two-pore theory. Physiol Rev 74, 163-219.
48. Smith, F.G. III & Deen, W.M. 1980. Electrostatic double-layer interactions for spherical colloids in cylindrical pores. J Coll Interface Sci 78, 444-465.
49. Tay, M., Comper, W.D. & Singh, A.K. 1991. Charge selectivity in kidney ultrafiltration is associated with glomerular uptake of transport probes. Am J Physiol 260, F549-F554.
50. Tisher, C.C. & Madsen, K.M. 1991. Anatomy of the kidney. In: B.M. Brenner & F.C. Rector (eds) The kidney, pp. 3-75. W. B. Saunders company, Philadelphia, PA.
51. Ueda, Y., Ono, Y., Sagiya, A., Kanaya, H. & Iidaka, K. 1992. Mesangial anionic sites are decreased in human focal glomerular sclerosis. Clin Nephrol 37, 280-284.
52. Vyas, S.V. & Comper, W.D. 1994. Dextran sulfate binding to isolated rat glomeruli and glomerular basement membrane. Biochim Biophys Acta 1201, 367-372.
53. Vyas, S.V., Parker, J.-A. & Comper, W.D. 1995. Uptake of dextran sulphate by glomerular intracellular vesicles during kidney ultrafiltration. Kidney Int 47, 945-950.
54. Weening, J.J. & Rennke, H.G. 1983. Glomerular permeability and polyanion in adriamycin nephrosis in the rat. Kidney Int 24, 152-159.
55. Wilkinson, A.H., Gillespie, C., Hartley, B. & Williams, D.G. 1989. Increase in proteinuria and reduction in number of anionic sites on the glomerular basement membrane in rabbits by infusion of human nephrotic plasma in vivo. Clin Sci 77, 43-48.
56. Wolgast, M., Källskog, Ö. & Wahlström, H. 1996a. Characteristics of the glomerular capillary membrane of the rat kidney as a hydrated gel. I Hypothetical structure Acta Physiol Scand 158, 213-224.
57. Wolgast, M., Källskog, Ö. & Wahlström, H. 1996b. Characteristics of the glomerular capillary membrane of the rat kidney as a hydrated gel. II On validity model Acta Physiol Scand 158, 225-232.