PAF mediates cigarette smoke-induced goblet cell metaplasia in guinea pig airways

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 280, Issue 3 24-3, 2001, Pages

  Komori, Masashi ^a   Inoue, Hiromasa ^a   Matsumoto, Koichiro ^a   Koto, Hiroshi ^a   Fukuyama, Satoru ^a   Aizawa, Hisamichi ^b   Hara, Nobuyuki ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b FUKUOKA HIGASHI MEDICAL CENTER   (Japan)

Author keywords

Hypersecretion; Platelet activating factor receptor antagonist; Trachea

Indexed keywords

CIGARETTE SMOKE; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR RECEPTOR;

AIRWAY; ANIMAL CELL; ARTICLE; CELL COUNT; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; EOSINOPHIL; GOBLET CELL; GUINEA PIG; LUNG LAVAGE; MALE; METAPLASIA; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL;

EID: 0034998154     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.280.3.l436     Document Type: Article

References (39)

1. Adler KB, Akley NJ, and Glasgow WC. Platelet-activating factor provokes release of mucin-like glycoproteins from guinea pig respiratory epithelial cells via a lipoxygenase-dependent mechanism. Am J Respir Cell Mol Biol 6: 550-556, 1992.
2. Aikawa T, Shimura S, Sasaki H, Ebina M, and Takishima T. Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. Chest 101: 916-921, 1992.
3. Ayers MM and Jeffery PK. Proliferation and differentiation in mammalian airway epithelium. Eur Respir J 1: 58-80, 1988.
4. Balzano G, Stefanelli F, Iorio C, De Felice A, Melillo EM, Martucci M, and Melillo G. Eosinophilic inflammation in stable chronic obstructive pulmonary disease. Relationship with neutrophils and airway function. Am J Respir Crit Care Med 160: 1486-1492, 1999.
5. Barnes PJ, Chung KF, and Page CP. Platelet-activating factor as a mediator of allergic disease. J Allergy Clin Immunol 81: 919-934, 1988.
6. Basbaum C, Lemjabbar H, Longphre M, Li D, Gensch E, and McNamara N. Control of mucin transcription by diverse injury-induced signaling pathways. Am J Respir Crit Care Med 160: S44-S48, 1999.
7. Blyth DI, Pedrick MS, Savage TJ, Bright H, Beesley JE, and Sanjar S. Induction, duration, and resolution of airway goblet cell hyperplasia in a murine model of atopic asthma: effect of concurrent infection with respiratory syncytial virus and response to dexamethasone. Am J Respir Cell Mol Biol 19: 38-54, 1998.
8. Fukuyama S, Inoue H, Aizawa H, Oike M, Kitaura M, Yoshie O, and Hara N. Effect of eotaxin and platelet-activating factor on airway inflammation and hyperresponsiveness in guinea pigs in vivo. Am J Respir Crit Care Med 161: 1844-1849, 2000.
9. Goswami SK, Ohashi M, Stathas P, and Marom ZM. Platelet-activating factor stimulates secretion of respiratory glycoconjugate from human airways in culture. J Allergy Clin Immunol 84: 726-734, 1989.
10. Greig N, Ayers M, and Jeffery PK. The effect of indomethacin on the response of bronchial epithelium to tobacco smoke. J Pathol 132: 1-9, 1980.
11. Harkema JR and Hotchkiss JA. Ozone-and endotoxin-induced mucous cell metaplasias in rat airway epithelium: novel animal models to study toxicant-induced epithelial transformation in airways. Toxicol Lett 68: 251-263, 1993.
12. 3H]SR 27417, on guinea-pig tracheal epithelial cells. Biochem J 284: 201-206, 1992.
13. Hirayama Y, Lei YH, Barnes PJ, and Rogers DF. Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo. Br J Pharmacol 108: 844-851, 1993.
14. Imaizumi T, Satoh K, Yoshida H, Kawamura Y, Hiramoto M, and Takamatsu S. Effect of cigarette smoking on the levels of platelet-activating factor-like lipid(s) in plasma lipoproteins. Atherosclerosis 87: 47-55, 1991.
15. Inoue H, Aizawa H, Nakano H, Matsumoto K, Kuwano K, Nadel JA, and Hara N. Nitric oxide synthase inhibitors attenuate ozone-induced airway inflammation in guinea pigs: possible role of interleukin-8. Am J Respir Crit Care Med 161: 249-256, 2000.
16. Jones R, Bolduc P, and Reid L. Goblet cell glycoprotein and tracheal gland hypertrophy in rat airways: the effect of tobacco smoke with or without the anti-inflammatory agent phenyl-methyloxadiazole. Br J Exp Pathol 54: 229-239, 1973.
17. Kaneko T, Ikeda H, Fu L, Nishiyama H, and Okubo T. Platelet-activating factor mediates the ozone-induced increase in airway microvascular leakage in guinea pigs. Eur J Pharmacol 292: 251-255, 1995.
18. Kang JX, Man SF, Hirsh AJ, and Clandinin MT. Characterization of platelet-activating factor binding to human airway epithelial cells: modulation by fatty acids and ion-channel blockers. Biochem J 303: 795-802, 1994.
19. Koike H, Imanishi N, Natsume Y, and Morooka S. Effects of platelet activating factor receptor antagonists on intracellular platelet activating factor function in neutrophils. Eur J Pharmacol 269: 299-309, 1994.
20. Kusano K, Tanaka S, Abe Y, Ida S, and Yuzuriha T. Pharmacokinetics of a new thienodiazepine platelet activating factor receptor antagonist (E6123) in laboratory animals. Is there a metabolic polymorphism in the rhesus monkey? Xenobiotica 23: 589-598, 1993.
21. Lamb D and Reid L. Mitotic rates, goblet cell increase and histochemical changes in mucus in rat bronchial epithelium during exposure to sulphur dioxide. J Pathol Bacteriol 96: 97-111, 1968.
22. Lamb D and Reid L. Goblet cell increase in rat bronchial epithelium after exposure to cigarette and cigar tobacco smoke. Br Med J 1: 33-35, 1969.
23. Lehr HA, Weyrich AS, Saetzler RK, Jurek A, Arfors KE, Zimmerman GA, Prescott SM, and McIntyre TM. Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J Clin Invest 99: 2358-2364, 1997.
24. Lou YP, Takeyama K, Grattan KM, Lausier JA, Ueki IF, Agusti C, and Nadel JA. Platelet-activating factor induces goblet cell hyperplasia and mucin gene expression in airways. Am J Respir Crit Care Med 157: 1927-1934, 1998.
25. Lundgren JD, Kaliner M, Logun C, and Shelhamer JH. Platelet activating factor and tracheobronchial respiratory glycoconjugate release in feline and human explants: involvement of the lipoxygenase pathway. Agents Actions 30: 329-337, 1990.
26. Matsumoto K, Aizawa H, Inoue H, Takata S, Shigyo M, and Hara N. Role of thromboxane A2 and cholinergic mechanisms in bronchoconstriction induced by cigarette smoke in guinea pigs. Eur Respir J 9: 2468-2473, 1996.
27. Miyaura S, Eguchi H, and Johnston JM. Effect of a cigarette smoke extract on the metabolism of the proinflammatory autacoid, platelet-activating factor. Circ Res 70: 341-347, 1992.
28. Pettipher ER, Salter ED, and Showell HJ. Effect of in vivo desensitization to leukotriene B4 on eosinophil infiltration in response to C5a in guinea-pig skin. Br J Pharmacol 113: 117-120, 1994.
29. Rogers DF. Airway goblet cells: responsive and adaptable front-line defenders. Eur Respir J 1: 1690-1706, 1994.
30. Rogers DF and Jeffery PK. Inhibition by oral N-acetylcysteine of cigarette smoke-induced "bronchitis" in the rat. Exp Lung Res 10: 267-283, 1986.
31. Rogers DF and Jeffery PK. Inhibition of cigarette smoke-induced airway secretory cell hyperplasia by indomethacin, dexamethasone, prednisolone, or hydrocortisone in the rat. Exp Lung Res 10: 285-298, 1986.
32. Roth MD, Arora A, Barsky SH, Kleerup EC, Simmons M, and Tashkin DP. Airway inflammation in young marijuana and tobacco smokers. Am J Respir Crit Care Med 157: 928-937, 1998.
33. Sakuma Y, Muramoto K, Harada K, Katayama S, Tsunoda H, and Katayama K. Inhibitory effects of a novel PAF antagonist E6123 on anaphylactic responses in passively and actively sensitized guinea pigs and passively sensitized mice. Prostaglandins 42: 541-555, 1991.
34. Snyder F. Platelet-activating factor: the biosynthetic and catabolic enzymes. Biochem J 305: 689-705, 1995.
35. Thompson AB, Daughton D, Robbins RA, Ghafouri MA, Oehlerking M, and Rennard SI. Intraluminal airway inflammation in chronic bronchitis. Characterization and correlation with clinical parameters. Am Rev Respir Dis 140: 1527-1537, 1989.
36. Tsunoda H, Sakuma Y, Shirato M, Obaishi H, Harada K, Yamada K, Shimomura N, Machida Y, Yamatsu I, and Katayama K. Activity of a novel thienodiazepine derivative as a platelet-activating factor antagonist in guinea pig lungs. Effects on platelet-activating factor and allergen induced eosinophil accumulation. Arzneimittelforschung 41: 224-227, 1991.
37. Woodward DF, Spada CS, Nieves AL, Hawley SB, and Williams LS. Platelet-activating factor causes goblet cell depletion in the conjunctiva. Eur J Pharmacol 168: 23-30, 1989.
38. Wright JL, Lawson LM, Pare PD, Wiggs BJ, Kennedy S, and Hogg JC. Morphology of peripheral airways in current smokers and ex-smokers. Am Rev Respir Dis 127: 474-477, 1983.
39. Zuhdi Alimam M, Piazza FM, Selby DM, Letwin N, Huang L, and Rose MC. Muc-5/5ac mucin messenger RNA and protein expression is a marker of goblet cell metaplasia in murine airways. Am J Respir Cell Mol Biol 22: 253-260, 2000.