Site-directed mutagenesis studies of rat steroid 5α-reductase (isozyme-1): Mutation of residues in the cofactor binding and C-terminal regions

Journal of Steroid Biochemistry and Molecular Biology

Volumn 77, Issue 2-3, 2001, Pages 177-182

  Bhattacharyya, A K ^a   Collins, D C ^a  

^a LEXINGTON VA MEDICAL CENTER   (United States)

Author keywords

C terminal regions; Cofactor binding; Isozyme 1; Mutation; Rat steroid 5 reductase; Site directed mutagenesis

Indexed keywords

GLYCINE; HISTIDINE; ISOENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; STEROID 5ALPHA REDUCTASE; TESTOSTERONE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BINDING; ENZYME KINETICS; ENZYME STABILITY; MICHAELIS CONSTANT; NONHUMAN; RAT; SITE DIRECTED MUTAGENESIS; VELOCITY;

AMINO ACID SEQUENCE; ANIMALS; ISOENZYMES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; RATS; TESTOSTERONE 5-ALPHA-REDUCTASE;

TRIXIS;

EID: 0034997154     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(01)00023-1     Document Type: Article

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