Neopterin production in SCID mice injected with human peripheral blood mononuclear cells

Immunobiology

Volumn 203, Issue 4, 2001, Pages 642-649

  Amadori, Alberto ^a   Wirleitner, Barbara ^b   Diez Ruiz, Antonio ^c   Veronesi, Arianna ^a   Chieco Bianchi, Luigi ^a   Fuchs, Dietmar ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF INNSBRUCK   (Austria)

^c UNIVERSITY OF GRANADA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

NEOPTERIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL CULTURE; CELL ISOLATION; CELL TRANSFER; CONTROLLED STUDY; EPSTEIN BARR VIRUS; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; INJECTION; LYMPHOBLASTOID CELL; LYMPHOMA; MEASUREMENT; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0034996696     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0171-2985(01)80013-9     Document Type: Article

References (25)

1. HUBER, C., J. R. BATCHELOR, D. FUCHS, A. HAUSEN, A. LANG, D. NIEDERWIESER, G. REIBNEGGER, P. SWETLY, J. TROPPMAIR, and H. WACHTER. 1984. Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma. J. Exp. Med. 160:310.
2. WERNER, E. R., G. WERNER-FELMAYER, D. FUCHS, A. HAUSEN, G. REIBNEGGER, J. J. YIM, W. PELEIDERER, and H. WACHTER. 1990. Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present. J. Biol. Chem. 265: 3189.
3. FUCHS, D., M. MALKOVSKY, G. REIBNEGGER, E. R. WERNER, G. FORNI, H. and WACHTER. 1989. Endogenous release of interferon-gamma and diminished response of peripheral blood mononuclear cells to antigenic stimulation. Immunol. Lett. 23:103.
4. FUCKS, D., A. HAUSEN, G. REIBNEGGER, E. R. WERNER, M. P. DIFRICH, and H. WACHTER. 1988. Neopterin as a marker for activated cell-mediated immunity: application in HIV infection. Immunol. Today 9: 150-155
5. FAHEY, J. L., J. M. TAYLOR, R. DETELS, B. HOFMANN, R. MELMED, P. NISHANIAN, and J. V. GIORGI. 1990. The prognostic value of cellular and serologic markers in infection with human immunodeficiency virus type 1. N. Engl. J. Med. 322: 166.
6. REIBNEGGER, G., C. AICHBERGER, D. FUCHS, A. HAUSEN, M. SPIELBERGER, E. R. WERNER, R. MARGREITER, and H. WACHTER. 1991. Posttransplant neopterin excretion in renal allograft recipients - a reliable diagnostic aid for acute rejection and a predictive marker of long-term graft survival. Transplantation 52: 58.
7. FUCHS, D., G. WEISS, and H. WACHTER. 1993. Neopterin, biochemistry and clinical use as a marker for cellular immune reactions. Int. Arch. Allergy Immunol. 101: 1.
8. SAMSONOV, M. Y., G. P. TILZ, O. EGOROVA, G. REIBNEGGER, R. M. BALABANOVA, E. L. NASSONOV, V. A. NASSONOV, H. WACHTER, and D. FUCHS. 1995. Serum soluble markers of immune activation and disease activity in systemic lupus erythematosus. Lupus 4: 29.
9. DICK, J. E., T. LAPIDOT, and F. PFLUMIO. 1991. Transplantation of normal and leukemic human hone marrow into immune-deficient mice: development of animal models for human hematopoiesis. Immunol. Rev. 124: 25.
10. SIMPSON, K., J. FARRANT, and P. CHANDLER. 1991. Phenotoypic and functional studies of human peripheral blood lymphocytes engrafted in scid mice. Immunol. Rev. 124: 97.
11. MOSIER, D. E., R. J. GULIZIA, S. M. BAIRD, and D. B. WILSON. 1988. Transfer of a functional human immune system to mice with severe combined immunodeficiency. Nature 335: 256.
12. ROWE, M., L. S. YOUNG, J. CROCKER, H. STOKES, S. HENDERSON, and A. B. RICKINSON, 1991. Epstein-Barr virus (EBV)-associated lymphoproliferative disease in the SCID mouse model: implications for the pathogenesis of EBV-positive lymphomas in man. J. Hxp. Med. 173: 147.
13. CANNON, M. J., P. PISA , R. I. Fox, and N. R. COOPER. 1990. Epstein-Barr virus induces aggressive lymphoproliferative disorders of human B cell origin in SCID/hu chimeric mice. J. Clin. Invest 85: 1333.
14. JOACHIM, H. L. 1990. The opportunistic tumors of immune deficiency. Adv Cancer Res 54: 301.
15. LEVINE, A. M. 1993. AIDS-related malignancies: the emerging epidemic. J. Natl. Cancer Inst. 85: 1382.
16. DUCH, D. S., S. W. BOWERS, J. H. WOOLF, and C. A. NICHOL,. 1984. Biopterin cofactor biosynthesis: CIP cyclohydrolase, neopterin and biopterin in tissues and body fluids of mammalian species. Life Sci. 35: 1895.
17. AMADORI, A., R. ZAMARCHI, V. CIMINALE, A. DEL-MISTRO, S. SIERVO, A. ALBERTI, M. COLOMBATTI, and L. CHIECO-BIANCHI. 1989. HIV-1-specific B cell activation: a major constituent of spontaneous B cell activation during HIV-1 infection. J. Immunol. 143: 2146.
18. VERONESE, M. L., A. VERONESI, E. D'ANDREA, A. DEL-MISTRO, S. INDRACCOLO, M. R. MAZZA, M. MION, R. ZAMARCHI, C. MENIN, and M. PANOZZO. 1992. Lymphoproliferative disease in human peripheral blood mononuclear cell-injected SCID mice. I. T-lymphocyte requirement for B-cell tumor generation. J. Exp. Med. 176: 1763.
19. VERONESE, M. L., A. VERONESI, L. BRUNI, V. COPPOLA, E. D'ANDRKA, A. DEL.-MISTRO, S. MEZZALIRA, M. MONTAGNA, G. RUFFATO, and A. AMADORI. 1994. Properties of tumors arising in SCID mice injected with PBMC form EBV-positive donors. Leukemia 8: 214.
20. th ed. Washington, D. D., American Society for Microbiology, 1992; 251.
21. COPPOLA, V., A. VERONESI, S. INDRACCOLO, F. CALDERAZZO, M. MION, S. MINUZZO, G. ESPOSITO, D. MAURO, B. SILVESTRI, P. GALLO, P. FAKAGIANI, A. AMADORI, and L. CHIECO-BIANCHI. 1998. Lymphoproliferative disease in human peripheral blood mononuclear cell-injected SCID mice. IV: Differential Activation of human Th1 and Th2 lymphocytes and influence of the a topic status on lymphoma development. J. Immunol. 160: 2514.
22. BITTERLICH, G., G. SZABÓ, E. R. WERNER, C. LARCHER, D. FUCHS, A. HAUSEN, G. REIBNEGGER, T. F. SCHULZ, J. TROPMMAIR, H. WACHTER, and M. P. DIERICH. 1988. Selective induction of mononuclear phagocytes to produce neopterin by interferons. Immunobiology 176: 228.
23. HOFMANN, B., H. BASS, and P. NISHANIAN. 1992. Different lymphoid cell populations produce varied levels of neopterin, beta-2-microglobulin and soluble IL-2 receptor when stimulated with IL-2, intcrferon-gamma or tumor necrosis factor-alpha. Clin. Exp. Immunol. 88: 548.
24. VERONESI, A., V. COPPOLA, M. L. VERONESE, C. MENIN, L. BRUNI, E. D'ANDREA, M. MION, A. AMADORI, and L. CHIECO-BIANCHI. 1994. Lymphoproliferative disease in human peripheral-blood-mononuclear-cell-injected-SCID mice. II. Role of host and donor factors in tumor generation. Int. J. Cancer 59: 676.
25. TARY-LEHMANN, M., A. SAXON, and P. V. LEHMANN. 1995. The human immune system in huPBL-SCID mice. Immunol. Today 16: 529.