When running a stop sign may be a good thing

Annals of Neurology

Volumn 49, Issue 6, 2001, Pages 693-694

  Karpati, George ^a   Lochmuller, Hanns ^b  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DYSTROPHIN; GENTAMICIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; BECKER MUSCULAR DYSTROPHY; DRUG MECHANISM; DUCHENNE MUSCULAR DYSTROPHY; EDITORIAL; EXPERIMENTAL ANIMAL; MOUSE; NONHUMAN; NONSENSE MUTATION; PATHOGENESIS; PRIORITY JOURNAL; REPRODUCIBILITY;

ANIMALS; CODON, NONSENSE; DYSTROPHIN; GENTAMICINS; HUMANS; MICE; MICE, INBRED MDX; MUSCULAR DYSTROPHY, DUCHENNE; SPECIES SPECIFICITY; TREATMENT OUTCOME;

EID: 0034994467     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.1056     Document Type: Editorial

References (12)

1. The dawning of a new era in the molecular biology of the muscular dystrophies
2. Animal models for muscular dystrophy: Valuable tools for the development of therapies
3. Developments in gene therapy for muscular dystrophy
4. Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice
5. Aminoglycoside antibiotics restore CFTR function by overcoming premature stop codon mutations
6. A pilot study of the effect of gentamicin on nasal potential difference measurements in cystic fibrosis patients carrying stop mutations
7. Gentamicin-mediated suppression of Hurler syndrome stop mutations restores a low level of α-L-iduronidase activity and reduces lysosomal glycosaminoglycan accumulation
8. Sequence specificity of aminoglycoside-induced stop condon readthrough: Potential implications for treatment of Duchenne muscular dystrophy
9. Gentamicin treatment of Duchenne and Becker muscular dystrophy due to nonsense mutations
10. Mdx mice inducibly expressing dystrophin provide insights into the potential of gene therapy for Duchenne muscular dystrophy
11. The influence of aminoglycoside antibiotics on the in vitro function of rat liver ribosomes
12. Structural origins of gentamicin antibiotic action