Improvement of water solubility of sulfamethizole through its complexation with β- and hydroxypropyl-β-cyclodextrin - Characterization of the interaction in solution and in solid state

European Journal of Pharmaceutical Sciences

Volumn 13, Issue 3, 2001, Pages 325-331

  Pose Vilarnovo, Beatriz ^a   Perdomo López, Iliana ^a   Echezarreta López, Magdalena ^a   Schroth Pardo, Patricia ^a   Estrada, Ernesto ^a   Torres Labandeira, Juan J ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

Cyclodextrin; Dissolution; Hydroxypropyl cyclodext rin; Molecular modelling; NMR; Sulfamethizole

Indexed keywords

COMPLEXATION; DIFFERENTIAL SCANNING CALORIMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLID STATE DEVICES; SOLUBILITY; SOLVENTS; X RAY POWDER DIFFRACTION;

PHASE SOLUBILITY;

DRUG PRODUCTS;

2 HYDROXYPROPYL BETA CYCLODEXTRIN; AMMONIUM DERIVATIVE; BETA CYCLODEXTRIN; SULFAMETHIZOLE; THIADIAZOLE DERIVATIVE;

AQUEOUS SOLUTION; ARTICLE; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG SOLUBILITY; DRUG STABILITY; FREEZE DRYING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID STATE; X RAY POWDER DIFFRACTION;

BETA-CYCLODEXTRINS; CALORIMETRY, DIFFERENTIAL SCANNING; CYCLODEXTRINS; EXCIPIENTS; FREEZE DRYING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; SOLUBILITY; SOLUTIONS; SULFAMETHIZOLE; WATER; X-RAY DIFFRACTION;

EID: 0034994382     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(01)00131-2     Document Type: Article

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