Effect of aggregation of amphotericin B on lysophosphatidylcholine micelles as related to its complex formation with cholesterol or ergosterol

Journal of Biochemistry

Volumn 129, Issue 5, 2001, Pages 725-732

  Kawabata, M ^a   Onda, M ^a   Mita, T ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

Amphotericin B; Complex formation; Ergosterol; Lysophosphatidylcholine; Micelle

Indexed keywords

AMPHOTERICIN B; CHOLESTEROL; ERGOSTEROL; LYSOPHOSPHATIDYLCHOLINE; STEROL;

ABSORPTION SPECTROSCOPY; ANIMAL CELL; ANISOTROPY; ARTICLE; CELL INTERACTION; COMPLEX FORMATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; MEMBRANE FLUIDITY; MICELLE; NONHUMAN; TEMPERATURE DEPENDENCE; THERMOSTABILITY;

ANIMALIA;

EID: 0034992092     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a002912     Document Type: Article

References (43)

1. Molecular dynamics of amphotericin B. II. Dimer in water
2. Deuterium NMR of amphotericin B derivative in mechanically aligned lipid bilayers
3. The structuring effect of amphotericin B on pure and ergosterol- or cholesterol-containing dipalmitoylphosphatidylcholine bilayers: A differential scanning calorimetry study
4. Phase behaviour of amphotericin B multilamellar vesicles
5. Effect of amphotericin B on dipalmitoylphosphatidylcholine membranes: Calorimetry, ultrasound absorption and monolayer technique studies
6. Unusual lipid structures selectively reduce the toxicity of amphotericin B
7. Effects of the detergent sucrose monolaurate on binding of amphotericin B to sterols and its toxicity for cells
8. The effect of surfactants on the aggregation state of amphotericin B
9. Temperature effects on the aggregation state and activity of amphotericin B
10. Effects of the aggregation state of amphotericin B on its toxicity to mice
11. Separation of overlapping spectra from evolving systems using factor analysis. 2. Amphotericin B in aqueous propanol and in aqueous lauroyl sucrose
12. Incorporation of amphotericin B into large unilamellar vesicles composed of phosphatidylcholine and phosphatidylglycerol
13. Development, characterization, efficacy and mode of action of AmBisome, a unilamellar liposomal formulation of amphotericin B
14. Serum pharmacology of amphotericin B applied in lipid emulsions
15. Amphotericin B in lipid emulsion: Stability, compatibility, and in vitro antifungal activity
16. 31P NMR study
17. Enhanced emulsifying ability of food surfactants by addition of lysophospholipids
18. Interaction of amphotericin B with cholesterol in monolayers, aqueous solutions, and phospholipid bilayers
19. Conformation of gramicidin in monolayers, organic solvents and phospholipid bilayers
20. The formation of amphotericin B ion channel in lipid bilayers
21. One-sided action of amphotericin B on cholesterol-containing membranes is determined by its self-association in the medium
22. Amphotericin B toxicity as related to the formation of oxidatively modified low-density lipoproteins
23. How do the polyene macrolide antibiotics affect the cellular membrane properties?
24. On the existence of an amphotericin B-sterol complex in lipid vesicles and in propanol-water systems
25. Effect of the aggregation state of amphotericin B on its interaction with ergosterol
26. Effect of the modifications of ionizable groups of amphotericin B on its ability to form complexes with sterols in hydroalcoholic media
27. Interaction between phospholipid bilayer membranes and the polyene antibiotic amphotericin B. Lipid state and cholesterol content dependence
28. Binding of nystatin and amphotericin with sterol-free L-dilauroylphosphatidylcholine bilayers resulting in the formation of dichroic lipid superstructures
29. Monolayer of cholesterol at water-air interface: Mechanism of collapse
30. Effects of aggregation and solvent on the toxicity of amphotericin B to human erythrocytes
31. In vitro dissociation of antifungal efficacy and toxicity for amphotericin B-loaded poly(ethylene oxide)-block-poly(β-benzyl-L-aspartate) micelles
32. Effect of aggregation state of amphotericin B incorporated into egg lecithin-bile salt mixed micelles: Molecular and cellular aspects relevant to therapeutic efficacy in experimental mycoses
33. Dissociation kinetics and equilibrium binding properties of polyene antibiotic complexes with phosphatidylcholine/sterol vesicles
34. A comparison of the activities of three amphotericin B lipid formulations against experimental visceral and cutaneous leishmaniasis
35. Steady-state fluorescence studies on lipase-vesicle interactions
36. Critical role of micelles in pancreatic lipase activation revealed by small angle neutron scattering
37. Gramicidin A induces lysolecithin to form bilayers
38. Amphotericin B lipid complex
39. 31P-NMR study
40. Theoretical study of the complexation of amphotericin B with sterols
41. Equilibrium binding of amphotericin B and its methyl ester and borate complex to sterols
42. Molecular organisation of amphotericin B at the air-water interface in the presence of sterols: A monolayer study
43. Temperature, stability, and the hydrophobic interaction