Cytogenetic findings and their clinical relevance in myelofibrosis with myeloid metaplasia

British Journal of Haematology

Volumn 113, Issue 3, 2001, Pages 763-771

  Tefferi, Ayalew ^a   Mesa, Ruben A ^a   Schroeder, Georgene ^a   Hanson, Curtis A ^a   Li, Chin Yang ^a   Dewald, Gordon W ^a  

^a MAYO CLINIC   (United States)

Author keywords

Bone marrow; Cytogenetics; Karyotype; Myelofibrosis with myeloid metaplasia; Myeloid disorders

Indexed keywords

ADULT; AGED; ARTICLE; CHROMOSOME 1; CHROMOSOME 5; CHROMOSOME 7; CLONE; CYTOGENETICS; FEMALE; HUMAN; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; MYELOFIBROSIS; MYELOID METAPLASIA; PARTIAL TRISOMY 9; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL TIME;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANEMIA; CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 5; CHROMOSOMES, HUMAN, PAIR 7; CHROMOSOMES, HUMAN, PAIR 9; FEMALE; HUMANS; KARYOTYPING; MALE; MIDDLE AGED; MYELOFIBROSIS; MYELOID METAPLASIA; PROGNOSIS; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 0034988764     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2001.02796.x     Document Type: Article

References (53)

1. The Italian consensus conference on diagnostic criteria for myelofibrosis with myeloid metaplasia
2. Molecular genetics and cytogenetics of myeloproliferative disorders
3. Treatment of polycythaemia vera: A summary of clinical trials conducted by the polycythaemia vera study group
4. Analysis of the androgen response of 23 patients with agnogenic myeloid metaplasia: The value of chromosomal studies in predicting response and survival
5. Patients with isolated trisomy 8 in acute myeloid leukemia are not cured with cytarabine-based chemotherapy: Results from Cancer and Leukemia Group B 8461
6. The prognostic significance of deletion of the long arm of chromosome 20 in myeloid disorders
7. Identification of 'short-lived' and 'longlived' patients at presentation of idiopathic myelofibrosis
8. Myelofibrosis with myeloid metaplasia in young individuals: Disease characteristics, prognostic factors and identification of risk groups
9. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
10. Cytogenetic studies and their prognostic significance in agnogenic myeloid metaplasia: A report on 47 cases
11. The t(15:17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus
12. Chromosome abnormalities in the myeloproliferative disorders
13. The efficacy of direct, 24-hour culture, and mitotic synchronization methods for cytogenetic analysis of bone marrow in neoplastic hematologic disorders
14. Hematopathologic findings in the myeloproliferative disorders
15. Chromosome studies in 104 patients with polycythaemia vera
16. Lessons learned from the development of an abl tyrosine kinase inhibitor for chronic myelogenous leukemia
17. Prognostic factors in agnogenic myeloid metaplasia: A report on 195 cases with a new scoring system
18. Long term treatment of myeloproliferative disease with interferon-alpha-2b: Feasibility and efficacy
19. International scoring system for evaluating prognosis in myelodysplastic syndromes
20. The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
21. Allogeneic stem cell transplantation for agnogenic myeloid metaplasia: A European Group for Blood and Marrow Transplantation, Societe Francaise de Creffe de Moelle, Cruppo Italiano Per Il Trapianto del Midollo Osseo, and Fred Hutchinson Cancer Research Center Collaborative Study
22. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
23. Agnogenic myeloid metaplasia: A clonal proliferation of hematopoietic stem cells with secondary myelofibrosis
24. Deletions of chromosome 13 in malignant hematologic disorders
25. Cytogenetics in chronic lymphocytic leukemia
26. Prognostic factors in idiopathic (primary) osteomyelofibrosis
27. Evidence for a 15;17 translocation in every patient with acute promyelocytic leukemia
28. Molecular delineation of 13q deletion boundaries in 20 patients with myeloid malignancies
29. Karyotypically distinct subpopulations in acute leukemia with specific growth requirements
30. Management of myelofibrosis with intermittent hydroxyurea
31. Transforming growth factor-beta and megakaryocytes in the pathogenesis of idiopathic myelofibrosis
32. Evaluation and clinical correlations of bone marrow angiogenesis in myelofibrosis with myeloid metaplasia
33. 32P between 1969 and 1981
34. Chromosome studies on normal and leukemic human leukocytes
35. Genetic analysis of chromosome 13 deletions in BCR/ABL negative chronic myeloproliferative disorders
36. Regional cancer cytogenetics: A report on 1,143 diagnostic cases
37. A chromosomal profile of polycythaemia vera
38. Pathogenesis of idiopathic myelofibrosis: Present status and future directions
39. Cytogenetic abnormalities and their prognostic significance in idiopathic myelofibrosis: A study of 106 cases
40. The significance of trisomy 8 in de novo acute myeloid leukaemia: The accompanying chromosome aberrations determine the prognosis
41. Incidence, characterization and prognostic significance of chromosomal abnormalities in 640 patients with primary myelodysplastic syndromes
42. Correlation of cytogenetic, molecular cytogenetic, and clinical findings in 59 patients with ANLL or MDS and abnormalities of the short arm of chromosome 12
43. A prospective long-term cytogenetic study in polycythaemia vera in relation to treatment and clinical course
44. Clonal evolutions during long-term cultures of bone marrow from de novo acute myeloid leukaemia with trilineage myelodysplasia and with myelodysplastic remission marrow
45. Frequent allelic loss of the RB, D13S319 and D13S25 locus in myeloid malignancies with deletion/translocation at 13q14 of chromosome 13, but not in lymphoid malignancies
46. Myelofibrosis with myeloid metaplasia
47. Splenectomy in myelofibrosis with myeloid metaplasia: A single-institution experience with 223 patients
48. A long-term retrospective study of young women with essential thrombocythemia
49. Translocations involving 12p in acute myeloid leukemia: Association with prior myelodysplasia and exposure to mutagenic agents
50. Frequent chromosome arm 13q deletion in aggressive non-Hodgkin's lymphoma
51. Cytogenetic studies of bone marrow fibroblasts cultured from patients with myelofibrosis and myeloid metaplasia
52. Karyotype findings and molecular analysis of the bcr gene rearrangement supplementing the histologic classification of chronic myeloproliferative disorders
53. Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization. Multi Center Investigation of bone marrow transplantation for sickle cell disease