Cytogenetic abnormalities and their prognostic significance in idiopathic myelofibrosis: A study of 106 cases

British Journal of Haematology

Volumn 98, Issue 1, 1997, Pages 96-102

  Reilly, J T ^a   Snowden, J A ^b   Spearing, R L ^b   Fitzgerald, P M ^b   Jones, N ^c   Watmore, A ^d   Potter, A ^d  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^b CHRISTCHURCH HOSPITAL   (New Zealand)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

^d Centre for Human Genetics   (United Kingdom)

Author keywords

Cytogenetics; Myelofibrosis; Prognostic factors

Indexed keywords

ADULT; AGED; ARTICLE; CYTOGENETICS; FEMALE; HUMAN; HUMAN CELL; IDIOPATHIC DISEASE; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MYELOFIBROSIS; MYELOPROLIFERATIVE DISORDER; PRIORITY JOURNAL; PROGNOSIS; STATISTICAL MODEL; SURVIVAL RATE;

EID: 0030748326     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.1722990.x     Document Type: Article

References (37)

1. Asimakopoulos, F.A. & Green, A.R. (1995) Deletions of chromosome 20q and the pathogenesis of myeloproliferative disorders. British Journal of Haematology, 95, 219-226.
2. Barosi, G., Berzuini, C., Liberato, L.N., Costa, A., Polino, G. & Ascari, E. (1988) A prognostic classification of myelofibrosis with myeloid metaplasia. British Journal of Haematology, 70, 397-401.
3. Besa, E.C., Nowell, P.C., Geller, N.L. & Gardner, F.M. (1982) Analysis of the androgen response of 23 patients with agnogenic myeloid metaplasia: the value of chromosomal studies in predicting response and survival. Cancer, 49, 308-313.
4. Borgsfröm, G.H., Knuutila, S., Ruutu, T., Pakkala, A., Lahtinen, R. & De la Chapelle, A. (1984) Abnormalities of chromosome 13 in myelofibrosis. Scandinavian Journal of Haematology, 33, 15-21.
5. Brown, A.G., Ross, F.M., Dunne, E.M., Steel, C.M. & Weir-Thompson. E.M. (1993) Evidence for a new suppressor locus (DBM ) in human B-cell neoplasia telomeric to the retinoblastoma gene. Nature Genetics, 3, 67-72.
6. Chelloul, N., Briere, J., Laval-Jeantet, M., Najean, Y., Vorhauer, W. & Jacquillat, C. (1975) Prognostic significance of myeloid metaplasia with myelotibrosis. Biomedicine, 24, 272-280.
7. Cox, D. (1972) Regression models and life tables. Journal of the Royal Statistical Society, B34, 187-203.
8. Demory, J.L., Dupriez, B., Fenaux, P., Lai, J.L., Beuscart, R., Jouet, J.P., Deminatti, M. & Bauters, F. (1988) Cytogenetic studies and their prognostic significance in agnogenic myeloid metaplasia: a report on 47 cases. Blood, 72, 855-859.
9. Dewald, G.W. & Wright, P.I. (1995) Chromosomal abnormalities in the myeloproliferative disorders. Seminars in Oncology, 22, 341-354.
10. Diez-Martin, J.L., Graham, D.L., Petitt, R.M. & Dewald, G.W. (1991) Chromosome studies in 104 patients with polycythemia. Mayo Clinic Proceedings, 66, 287-299.
11. Dupriez, B., Morel, P., Demory, J.L., Lai, J.L., Simon, M., Plantier, L. & Bautiers, F. (1996) Prognostic factors in agnogenic myeloid metaplasia: a report on 195 cases with a new scoring system. Blood, 88, 1013-1018.
12. Emilia, G., Sacchi, S., Temperani, P., Longo, R. & Vecchi, H. (1993) Progression of essential thrombocythemia to blastic crisis via idiopathic myelofibrosis. Leukemia and Lymphoma, 9, 423-426.
13. Hasselbalch, J. & Jensen, B.A. (1990) Prognostic factors in idiopathic myelofibrosis: a simple scoring system with prognostic significance. European Journal of Haematology, 44, 172-178.
14. Iványi, J.L., Mahunka, M., Papp, A., Kiss, A. & Telek, B. (1994) Prognostic significance of bone marrow reticulin fibres in idiopathic myelofibrosis: evaluation of clinicopathological parameters in a scoring system. Haematologyica, 26, 75-86.
15. Kaplan, E.L. & Meier, P. (1958) Nonparametric estimations from incomplete observations. Journal of the American Statistical Association, 53, 457-481.
16. Manorharan, A. (1988) Myelofibrosis: prognostic factors and treatment. British Journal of Haematology, 69, 295-298.
17. Mertens, F., Johansson, B., Heim, S., Kristoffersson, U. & Mitelman, F. (1991) Karyotypic patterns in chronic myeloproliferative disorders: report on 74 cases and review of the literature. Leukemia, 5, 214-220.
18. Miller, J.B., Testa, J.R., Lindgren, V. & Rowley, J.D. (1985) The pattern and clinical significance of karyotypic abnormalities in patients with idiopathic and postpolycythemic myelofibrosis. Cancer, 55, 582-591.
19. Morris, C.M., Cochrane, J.M., Benjes, S.M., Crossen, P.E. & Fitzgerald. P.H. (1991) Molecular definition of interstitial deletions chromosome 13 in leukemic cells. Genes, Chromosomes and Cancer, 3, 455-460.
20. Musilove, J. & Michalova, K. (1988) Chromosome study of 85 patients with myelodysplastic syndrome. Cancer Genetics and Cytogenetics, 33, 39-50.
21. Njoku, O.S., Lewis, S.M., Catovsky, D. & Gordon-Smith, E.C. (1983) Anaemia in myelofibrosis: its value in prognosis. British Journal of Haematology, 54, 70-89.
22. Pagliuca, A., Layton, D.M., Manoharan, A., Gordon, S., Green, P.J. & Mufti, G.J. (1989) Myelofibrosis in primary myelodysplastic syndromes: a clinico-pathological study of 10 cases. British Journal of Haematology, 71, 499-504.
23. Pastore, C., Nomdedeu, J., Volpe, G., Guerrasio, A., Cambrin, G.R., Parvis, G., Pautasso, M., Daglio, C., Mazza, U., Saglio, G. & Gaidano, G. (1995) Genetic analysis of chromosomal 13 deletions in BCR/ABL negative chronic myeloproliferative disorders. Genes. Chromosomes and Cancer, 14, 106-111.
24. Rege-Cambrin, G., Mecucci, C. & Tricot, G. (1987) A chromosomal profile of polycythemia. Cancer Genetics and Cytogenetics, 25, 233-245.
25. Reilly, J.T. (1994) Pathogenesis of idiopathic myelofibrosis: present status and future directions. British Journal of Haematology, 88, 1-8.
26. Reilly, J.T. & Dolan, G. (1991) Proposed classification for the myelodysplasia/myelofibrosis syndromes. British Journal of Haematology, 79, 653.
27. Reilly, J.T., Wilson, G., Barnett, D., Watmore, A. & Potter, A. (1994) Karyotypic and ras gene mutational analysis in idiopathic myelofibrosis. British Journal of Haematology, 88, 575-581.
28. Rupoli, S., Da Lio, L., Sisti, S., Campanati, G., Salvi, A., Brianzoni, M.F., D'Amico, S., Cincirpini, A. & Leoni, P. (1994) Primary myelofibrosis: a detailed statistical analysis of the clinicopathological variables influencing survival. Annals of Hematology, 68, 205-212.
29. Sandberg, A.A. (1990) The Chromosomes in Human Cancer and Leukemia. 2nd edn. Elsevier, New York.
30. Silverstein, M.N. (1983) Agnogenic myeloid metaplasia. Hematology (ed. by W. J. Williams, E. Beutler, A. J. Erslev and M. A. Lichtman), pp. 214-218. McGraw-Hill. New York.
31. Smadja, N., Krulik, M., Gramont, A. de, Sirinelli, A., Brissaud, P., Dray, C., Audebert, A.A. & Debray, J. (1987) Cytogenetic studies in twelve patients with primary myelofibrosis and myeloid metaplasia. Cancer Genetics and Cytogenetics, 24, 151-158.
32. Singhal, S., Powles, R., Treleaven, J., Pollard, C., Lumley, H. & Mehta, J. (1995) Alloyeneic bone marrow transplantation for primary myelofibrosis. Bone Marrow Transplantation, 16, 743-746.
33. Swolin, B., Weinfeld, A. & Westin, J. (1988) A prospective long-term cylogenetic study in polycythemia vera in relation to treatment and clinical course. Blood, 72, 386-395.
34. Varki, A., Lottenberg, R., Griffith, R. & Reinhard, E. (1983) The syndrome of idiopathic myelotibrosis: a clinicopathologic review with emphasis on the prognostic variables predicting survival. Medicine, 62, 353-371.
35. Visani, G., Finelli, C.,. Castelli, U., Petti, M.C., Ricci, P., Vianelli, N., Gianni, L., Zuffa, E., Spiriti, M.A.A., Latagliata, R., Pileri, S., Magrini, U., Gugliotta, L., Morra, E., Bernasconi, C., Mandelli, F. & Tura, S. (1990) Myelofibrosis with myeloid metaplasia: clinical and haematological parameters predicting survival in a series of 133 patients. British Journal of Hematology, 75, 4-9.
36. Ward, H.P. & Block, M.H. (1971) The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with the myeloproliferative syndrome. Medicine (Baltimore), 50, 357-420.
37. Whang-Peng, J., Lee, E., Knutsen, T., Chang, P. & Nienhuis. A. (1978) Cytogenetic studies in patients with myelofibrosis and myeloid metaplasia, Leukemia Research, 2, 41-56.