The evolution of an alternatively spliced exon in the αA-crystallin gene

Journal of Molecular Evolution

Volumn 52, Issue 6, 2001, Pages 510-515

  Van Dijk, Marjon A M ^a   Sweers, Marcel A M ^a   De Jong, Wilfried W ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Alternative splicing; Molecular evolution; Protein evolution; A Crystallin

Indexed keywords

ALPHA CRYSTALLIN;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; DNA SEQUENCE; EXON; EYE DEVELOPMENT; GENE STRUCTURE; HUMAN; HUMAN CELL; LENS; MOLECULAR EVOLUTION; NONHUMAN; PROTEIN EXPRESSION; SILENCER GENE; SPECIES DIFFERENTIATION;

ANIMALIA; MACROPUS SP.; MAMMALIA; RODENTIA;

EID: 0034984396     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002390010181     Document Type: Article

References (32)

1. The expanding small heat-shock protein family, and structure predictions of the conserved "α-crystallin domain"
2. Human erythroid 5-aminolevulinate synthase: Gene structure and species-specific differences in alternative RNA splicing
3. ISIS, the intron information system, reveals the high frequency of alternative splicing in the human genome
4. A comprehensive set of sequence analysis programs for the VAX
5. Determinants of 4-repeat tau expression: Coordination between enhancing and inhibitory splicing sequences for exon 10 inclusion
6. Alternative splicing of human genes: More the rule than the exception?
7. Monoclonal antibodies reveal evolutionary conservation of alternative splicing of the αA-crystallin primary transcript
8. Using CLUSTAL for multiple sequence alignments
9. α-Crystallin can function as a molecular chaperone
10. Functional characterization of two cholecystokinin-B/gastrin receptor isoforms: A preferential splice donor site in the human receptor gene
11. A pseudo-exon in the functional human αA-crystallin gene
12. ins-crystallin in mammals
13. A simple method for estimating evolutionary rate of base substitutions through comparative studies of nucleotide sequences
14. Alternative RNA splicing of the murine αA-crystallin gene: Protein-coding information within an intron
15. The structure and function of proteins involved in mammalian pre-mRNA splicing
16. Species-specific regulation of alternative splicing in the C-terminal region of the p53 tumor suppressor gene
17. Alternative splicing of pre-mRNA: Developmental consequences and mechanisms of regulation
18. Species specificity and organ, cellular and subcellular localization of the 100 kDa Ras GTPase activating protein
19. Splicing signals in Drosophila: Intron size, information content, and consensus sequences
20. A-Tropomyosin mutually exclusive exon selection: Competition between branch-point/polypyrimidine tracts determines default exon choice
21. Alternative splicing of SV40 early pre-mRNA is determined by branch site selection
22. Sequence divergence associated with species-specific splicing of the nonmuscle a-tropomyosin alternative exon
23. Alternative splicing generates four different forms of a non-transmembrane protein tyrosine phosphatase mRNA
24. Exon definition may facilitate splice site selection in RNAs with multiple exons
25. Alternative splicing in the control of gene expression
26. ins-crystallin, an alternative splicing product containing a large insert peptide
27. The rodent αA-crystallin gene: Mutagenesis of a non-consensus 5′-splice site to study alternative splicing in vivo
28. Effect of 5′ splice site mutations on splicing of the preceding intron
29. Intron definition in splicing of small Drosophila introns
30. The association of nonsense codons with exon skipping
31. Protein sequence signatures support the 'African clade' of mammals