An amino acid substitution in the coding region of the E2 glycoprotein adapts ross river virus to utilize heparan sulfate as an attachment moiety

Journal of Virology

Volumn 75, Issue 14, 2001, Pages 6303-6309

  Heil, M L ^a   Albee, A ^a   Strauss, J H ^a   Kuhn, R J ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ASPARAGINE; COMPLEMENTARY DNA; GLYCOPROTEIN; HEPARAN SULFATE; HEPARIN LYASE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; CELL STRAIN BHK; CHICKEN; CHO CELL; CONTROLLED STUDY; EMBRYO; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; ROSS RIVER ALPHA VIRUS; SITE DIRECTED MUTAGENESIS; VERO CELL;

AMINO ACID SUBSTITUTION; ANIMALS; CELL MEMBRANE; CELLS, CULTURED; CHICK EMBRYO; HEPARIN; HEPARIN LYASE; HEPARITIN SULFATE; POINT MUTATION; PROTEIN BINDING; ROSS RIVER VIRUS; SEPHAROSE; VIRAL ENVELOPE PROTEINS; VIRUS REPLICATION;

EID: 0034984146     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.14.6303-6309.2001     Document Type: Article

References (32)

1. An epidemic of Ross River virus infection in Fiji, 1979
2. Mutations in the E2 glycoprotein of Venezuelan equine encephalitis virus confer heparan sulfate interaction, low morbidity, and rapid clearance from blood of mice
3. Genetic stability of Ross River virus during epidemic spread in nonimmune humans
4. Binding of Sindbis virus to cell surface heparan sulfate
5. Large-plaque mutants of Sindbis virus show reduced binding to heparan sulfate, heightened viremia, and slower clearance from the circulation
6. Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate
7. The isolation of a third group A arbovirus in Australia, with preliminary observations on its relationship to epidemic polyarthritis
8. The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex
9. Human papillomavirus infection requires cell surface heparan sulfate
10. Alphavirus pathogenesis and immunity
11. Characterisation of a genetically engineered E2 deletion mutant of Ross River virus
12. Characterization of a Chinese hamster ovary cell line developed by retroviral insertional mutagenesis that is resistant to Sindbis virus infection
13. Ross River virus variants selected during passage in chick embryo fibroblasts: Serological, genetic, and biological changes
14. The furin protease cleavage recognition sequence of Sindbis virus PE2 can mediate virion attachment to cell surface heparan sulfate
15. Adaptation of Sindbis virus to BHK cells selects for use of heparan sulfate as an attachment receptor
16. Heparin-dependent attachment of respiratory syncytial virus (RSV) to host cells
17. Infectious RNA transcripts from Ross River virus cDNA clones and the construction and characterization of defined chimeras with Sindbis virus
18. Rapid and efficient site-specific mutagenesis without phenotypic selection
19. Ross River virus and epidemic polyarthritis
20. Sulfated polymers inhibit the interaction of human cytomegalovirus with cell surface heparan sulfate
21. FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides
22. Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells
23. Structural localization of the E3 glycoprotein in attenuated Sindbis virus mutants
24. Production of infectious RNA transcripts from Sindbis virus cDNA clones: Mapping of lethal mutations, rescue of a temperature sensitive marker, and in vitro mutagenesis to generate defined mutants
25. Putative receptor binding sites on alphaviruses as visualized by cryoelectron microscopy
26. Cellular receptors for alphaviruses
27. The alphaviruses: Gene expression, replication, and evolution
28. Ross River virus mutant with a deletion in the E2 gene: Properties of the virion, virus-specific macromolecule synthesis, and attenuation of virulence for mice
29. Location of a major antigenic site involved in Ross River virus neutralization
30. Entry kinetics and mouse virulence of Ross River virus mutants altered in neutralization epitopes
31. Initial interaction of herpes simplex virus with cells is binding to heparan sulfate
32. Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor