Heat shock preconditioning and pretreatment with glucocorticoid antagonist RU 486 protect rat myogenic cells H9c2 against glutamate-induced cell death

Molecular and Cellular Biochemistry

Volumn 220, Issue 1-2, 2001, Pages 25-30

  Gursoy, E ^a   Cardounel, A ^a   Kalimi, M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glucocorticoid receptors; Glutamate toxicity; H9c2 myoblasts; Heat shock; Immunofluorescence; RU 486

Indexed keywords

AMINO ACID; GLUCOCORTICOID ANTAGONIST; GLUCOCORTICOID RECEPTOR; GLUTAMIC ACID; LACTATE DEHYDROGENASE; MIFEPRISTONE;

ANIMAL CELL; ARTICLE; CARDIOTOXICITY; CELL DEATH; CELL PROTECTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; HEART MUSCLE CELL; HEART PROTECTION; HEAT SHOCK; IMMUNOFLUORESCENCE MICROSCOPY; LETHALITY; MYOBLAST; NONHUMAN; RAT;

ANIMALS; CELL DEATH; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMATES; HEAT; HORMONE ANTAGONISTS; ISCHEMIC PRECONDITIONING, MYOCARDIAL; L-LACTATE DEHYDROGENASE; MICROSCOPY, CONFOCAL; MIFEPRISTONE; MYOCARDIUM; RATS; RECEPTORS, GLUCOCORTICOID; TIME FACTORS;

EID: 0034982223     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011062808323     Document Type: Article

References (19)

1. Oxidative stress, glutamate, and neurodegenerative disorders
2. Amplification of glutamate-induced oxidative stress
3. Potential cardiovascular applications of glutamate, aspartate and other amino acids
4. Release of the excitatory amino acids, glutamate and aspartate, from the isolated ischemic/anoxic rat heart
5. Effects of L-glutamine on post-ischemic cardiac function, protection and rescue
6. Monosodium L-glutamate: Its pharmacology and role in the Chinese restaurant syndrome
7. Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart
8. Insulin-like growth factor I modulates induction of apoptotic signaling in H9c2 Cardiac muscle cells
9. NADPH-oxidase-dependent superoxide production by myocyte-derived H9c2 cells: Influence of ischemia, heat shock, cycloheximide and cytochalasin D
10. Stable expression of a human HSP70 gene in a rat myogenic cell line confers protection agaist endotoxin
11. A physiologically relevant hyperthermia selectively activates constitutive hsp70 in H9c2 cardiac myoblasts and confers oxidative protection
12. L-glutamate-induced changes in intracellular calcium oscillation frequency through non-classical glutamate receptor binding in cultured rat myocardial cells
13. Dehydroepiandrosterone protects hippocampal neurons against neurotoxin-induced cell death: Mechanism of action
14. Antioxidants, oxidative stress, and degenerative neurological disorders
15. Heat-shock response is associated with enhanced post ischemic ventricular recovery
16. Myocardial preconditioning: Basic concepts and potential mechanisms
17. Glucocorticoids increase the accumulation of reactive oxygen species and enhance adriamycin-induced toxicity in neuronal culture
18. Glutamate augments retrovirus-induced immunodeficiency through chronic stimulation of the hypothalamic-pituitary-adrenal axis
19. Hypothalamic mechanisms mediating glutamate effects on the hypothalamo-pituitary-adrenocortical axis