Tolerance to the antinociceptive effect of Crotalus durissus terrificus snake venom in mice is mediated by pharmacodynamic mechanisms

Toxicon

Volumn 39, Issue 9, 2001, Pages 1399-1410

  Brigatte, P ^a   Hoffmann, F A ^a   Bernardi, M M ^b   Giorgi, R ^a   Fernandes, I ^a   Takehara, H A ^a   Barros, S B M ^b   Almeida, M G ^c   Cury, Y ^a  

^a INSTITUTO BUTANTAN   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

Antinociception; Cross tolerance; Crotalus durissus terrificus snake venom; Opioid receptors; Tolerance

Indexed keywords

DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR ANTAGONIST; MORPHINE; N,N DIALLYLTYROSYL 2 METHYLALANYL 2 METHYLALANYLPHENYLALANYLLEUCINE; PENTOBARBITAL; SNAKE VENOM;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG CROSS TOLERANCE; DRUG EFFECT; DRUG MECHANISM; HOT PLATE TEST; LONG TERM CARE; MALE; MOTOR ACTIVITY; MOUSE; NONHUMAN; PAIN ASSESSMENT; PAIN THRESHOLD; PRIORITY JOURNAL; SLEEP TIME; WITHDRAWAL SYNDROME;

ANALGESICS; ANIMALS; BEHAVIOR, ANIMAL; CROTALID VENOMS; DRUG TOLERANCE; ENZYME-LINKED IMMUNOSORBENT ASSAY; MALE; MICE; MOTOR ACTIVITY; NARCOTIC ANTAGONISTS; PAIN MEASUREMENT; PSYCHOMOTOR PERFORMANCE; REACTION TIME; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANCE-RELATED DISORDERS;

ANIMALIA; CROTALUS; CROTALUS DURISSUS TERRIFICUS; SERPENTES;

EID: 0034981896     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-0101(01)00099-X     Document Type: Article

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