The broad-spectrum anti-emetic activity of AS-8112, a novel dopamine D2, D3 and 5-HT3 receptors antagonist

British Journal of Pharmacology

Volumn 133, Issue 2, 2001, Pages 253-260

  Yoshikawa, T ^a   Yoshida, N ^a   Oka, M ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Antiemetic; AS 8112

Indexed keywords

2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 5 BROMO N (1 ETHYL 4 METHYLHEXAHYDRO 1,4 DIAZEPIN 6 YL) 2 METHOXY 6 METHYLAMINONICOTINAMIDE; 5 BROMO N (1 ETHYL 4 METHYLHEXAHYDRO 1H 1,4 DIAZEPIN 6 YL) 2 METHOXY 6 METHYLAMINO 3 PYRIDINECARBOXAMIDE 2 FUMARATE; ANTIEMETIC AGENT; APOMORPHINE; CISPLATIN; CYCLOPHOSPHAMIDE; DOMPERIDONE; DOPAMINE 2 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR BLOCKING AGENT; DOPAMINE 3 RECEPTOR STIMULATING AGENT; DOXORUBICIN; GRANISETRON; HALOPERIDOL; METOCLOPRAMIDE; MORPHINE; ONDANSETRON; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DOG; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; FERRET; GUINEA PIG; HYPOTHERMIA; MALE; NONHUMAN; PRIORITY JOURNAL; VOMITING;

EID: 0034980902     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704078     Document Type: Article

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