The role of surfactant-associated protein A in pulmonary host defense

Immunologic Research

Volumn 23, Issue 2-3, 2001, Pages 111-120

  Shepherd, V L ^a   Lopez, J P ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Innate Immunity; Macrophages; Mycobacteria; Surfactant Protein A

Indexed keywords

CARBOHYDRATE; LECTIN; LUNG SURFACTANT; NITRIC OXIDE; SURFACTANT PROTEIN A;

ARTICLE; CELL INTERACTION; HOST RESISTANCE; HUMAN; INFECTION RESISTANCE; LECTIN BINDING; LUNG ALVEOLUS MACROPHAGE; LUNG ALVEOLUS SURFACE TENSION; MACROPHAGE ACTIVATION; MYCOBACTERIUM; OPSONIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN INTERACTION; RESPIRATORY TRACT INFECTION;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PHYSIOLOGY; CHEMOTAXIS; HUMANS; IMMUNITY, NATURAL; INFLAMMATION MEDIATORS; LECTINS; LUNG; MACROPHAGES, ALVEOLAR; MEMBRANE GLYCOPROTEINS; MICE; MYCOBACTERIUM; OPSONIN PROTEINS; PHAGOCYTOSIS; PROTEOLIPIDS; PULMONARY SURFACTANT-ASSOCIATED PROTEIN A; PULMONARY SURFACTANT-ASSOCIATED PROTEINS; PULMONARY SURFACTANTS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 0034979340     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1385/IR:23:2-3:111     Document Type: Article

References (52)

1. Immunomodulatory functions of surfactant
2. Surface active materials from dog lung. II. Composition and physiological correlations
3. Surfactant protein A is opsonin in phagocytosis of herpes simplex virus type 1 by rat alveolar macrophages
4. Collectins - Soluble proteins containing collagenous regions and lectin domains and their roles in innate immunity
5. Collectins and pulmonary immunity
6. The C-type lectin superfamily in the immune system
7. Surfactant protein A (SP-A): The alveolus and beyond
8. Surfactant apoprotein in adult rat lung compartments is increased by dexamethasone
9. The major lung surfactant protein, SP 28-36, is a calcium-dependent, carbohydrate-binding protein
10. Surfactant protein A (SP-A) mediates attachment of Mycobacterium tuberculosis to murine alveolar macrophages
11. Pulmonary surfacrant protein A mediates enhanced phagocytosis of Mycobacterium tuberculosis by a direct interaction with human macrophages
12. S P-A enhances uptake of bacillus Calmette-Guerin by macrophages through a specific SP-A receptor
13. Suffactant protein A enhances Mycobacterium avium complex-induced inflammatory mediator production but not clearance
14. SP-A enhances phagocytosis of Klebsiella by interaction with capsular polysaccharides and alveolar macrophages
15. Suffactant protein A mediates mycoplasmacidal activity of alveolar macrophages
16. Surfactant protein A stimulates phagocytosis of specific pulmonary pathogens by alveolar macrophages
17. Surfactant protein-A binds group B Streptococcus enhancing phagocytosis and clearance from lungs of surfactant protein-a deficient mice
18. Pulmonary surfactant protein A binds to Cryptococcus neoformans without promoting phagocytosis
19. Comparison of the opsonic activity of human surfactant protein A for Staphylococcus aureus and Streptococcus pneumoniae with rabbit and human macrophages
20. Surfactant protein A enhances alveolar macrophage phagocytosis of a live, mucoid strain of P. aeruginosa
21. Human surfactant protein A enhances attachment of Pneumocystis carinii to rat alveolar macrophages
22. Phagocytosis of viable Candida albicans by alveolar macrophages: Lack of opsonin function of surfactant protein A
23. SP-A enhances viral clearance and inhibits inflammation after pulmonary adenoviral infection
24. Mediation of entry of human immunodeficiency virus-1 into alveolar macrophages by CD4 without facilitation by surfactant-associated protein A
25. Surfactant protein-A enhances respiratory syncytial virus clearance in vivo
26. Surfactant protein-A enhances uptake of respiratory syncytial virus by monocytes and U937 macrophages
27. Surfactant protein A binding to cytomegalovirus proteins enhances virus entry into rat lung cells
28. Surfactant proteins A and D specifically stimulate directed actin-based responses in alveolar macrophages
29. Surfactant protein A modulates release of reactive oxygen species from alveolar macrophages
30. Human pulmonary surfactant protein A (SP-A), a protein structurally homologous to Clq, can enhance FcR- and CRl-mediated phagocytosis
31. Binding of surfactant protein A to Clq receptors mediates the phagocytosis of Staphylococcus aureus by monocytes
32. Surfactant protein A activates NF-κ B in the THP-1 monocytic cell line
33. Nitric oxide production by rat alveolar macrophages can be modulated in vitro by surfactant protein A
34. Surfactant protein A protects growing cells and reduces tumor necrosis factor-alpha release from lipopolysaccharide-stimulated macrophages
35. Surfactant protein A enhances mycobacterial killing by rat macrophages through a nitric oxide-dependent pathway
36. Surfactant protein A differentially regulates IFN-gamma- and LPS-induced nitric oxide production by rat alveolar macrophages
37. Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo
38. Human leukocyte Clq receptor binds other soluble proteins with collagen domains
39. Alveolar type II cells express a high-affinity receptor for pulmonary surfactant protein A
40. Specific binding of surfactant protein A to rat alveolar macrophages
41. Purification of a cell-surface receptor for pulmonary surfactant protein A
42. Surfactant protein A from human immunodeficiency virus-infected individuals promotes attachment of Mycobacterium tuberculosis to alveolar macrophages
43. Mechanisms of host defense against Candida species. I. Phagocytosis by monocytes and monocyte-derived macrophages
44. Surfactant metabolism in surfactant protein A-deficient mice
45. Lung suffactant protein A (SP-A) activates a phosphoinositide/calcium signalling pathway in alveolar macrophages
46. Regulation of protein phosphorylation and pathogen phago cytosis by surfactant protein A
47. The role of tyrosine kinases and MAP kinases in LPS-induced signaling
48. Tyrosine phosphorylation is involved in SPA/mycobacterium-induced signaling in rat macrophages
49. Suffactant protein A enhances bacillus Calmette-Guerin-induced ERK signaling in rat macrophages
50. Surfactant protein A enhances bacillus Calmette-Guerin-induced activation of NF-κ B in mononuclear phagocytes
51. Molecular composition of the macrophage SP-R210 signaling complex
52. Differential regulation of the mannose and SP-A receptors on macrophages