Treatment with interferon-alpha (IFNα) of hepatitis C patients induces lower serum dipeptidyl peptidase IV activity, which is related to IFNα-induced depressive and anxiety symptoms and immune activation

Molecular Psychiatry

Volumn 6, Issue 4, 2001, Pages 475-480

  Maes, M ^a,b   Bonaccorso, S ^a,b,c   Marino, V ^c   Puzella, A ^c   Pasquini, M ^c   Biondi, M ^c   Artini, M ^c   Almerighi, C ^c   Meltzer, H ^b  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VANDERBILT UNIVERSITY   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Anxiety; Cytokines; Depression; Dipeptidyl peptidase IV; Interferon; Peptidases

Indexed keywords

CYTOKINE; DIPEPTIDYL PEPTIDASE IV; INTERLEUKIN 8; KYNURENINE; RECOMBINANT ALPHA2A INTERFERON; TRYPTOPHAN;

ADULT; ANXIETY NEUROSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DEPRESSION; DISEASE SEVERITY; DOSE TIME EFFECT RELATION; ENZYME ACTIVITY; FEMALE; HEPATITIS C; HUMAN; IMMUNOTHERAPY; INFLAMMATION; LONG TERM CARE; MALE; PRIORITY JOURNAL; SCORING SYSTEM; TREATMENT OUTCOME; TRYPTOPHAN METABOLISM;

ADULT; ANALYSIS OF VARIANCE; ANTIGENS, CD26; ANTIVIRAL AGENTS; ANXIETY DISORDERS; BIOLOGICAL MARKERS; DEPRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEPATITIS C, CHRONIC; HUMANS; INFLAMMATION; INTERFERON ALFA-2A; INTERLEUKIN-8; MALE; PSYCHIATRIC STATUS RATING SCALES; REGRESSION ANALYSIS; TIME FACTORS;

EID: 0034979210     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000872     Document Type: Article

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