Lazaroid compounds prevent early but not late stages of oxidant-induced cell injury: Potential explanation for the lack of efficacy of lazaroids in clinical trials

Pharmacological Research

Volumn 43, Issue 1, 2001, Pages 55-61

  Huang, Hong ^a   Patel, Prakash B ^a   Salahudeen, Abdulla K ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Free radicals; Lazaroids; Lipid peroxidation

Indexed keywords

2 [[4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL]METHYL] 3,4 DIHYDRO 2,5,7,8 TETRAMETHYL 2H 1 BENZOPYRAN 6 OL; ADENOSINE TRIPHOSPHATE; DEFEROXAMINE; DNA; HYDROGEN PEROXIDE; LACTATE DEHYDROGENASE; LAZAROID;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL DIVISION; CELL PROTECTION; CONTROLLED STUDY; DNA DAMAGE; DRUG EFFICACY; ENZYME RELEASE; KIDNEY TUBULE CELL; LIPID PEROXIDATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0034978941     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.2000.0740     Document Type: Article

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