Paradoxical effects of tissue inhibitor of metalloproteinases 1 gene transfer in collagen-induced arthritis

Arthritis and Rheumatism

Volumn 44, Issue 6, 2001, Pages 1444-1454

  Apparailly, Florence ^a,d   Nol, Danièle ^a   Millet, Virginie ^a   Baker, Andrew H ^b   Lisignoli, Gina ^c   Jacquet, Chantal ^d   Kaiser, Marie Jolle ^a   Sany, Jacques ^b   Jorgensen, Christian ^d  

^a INSERM   (France)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^d LAPEYRONIE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; GELATINASE B; INTERSTITIAL COLLAGENASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EXPRESSION VECTOR; EXTRACELLULAR MATRIX; GENE TRANSFER; HISTOPATHOLOGY; HUMAN; INFLAMMATION; MALE; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RADIODIAGNOSIS;

ADENOVIRIDAE; ANIMALS; ARTHRITIS, EXPERIMENTAL; CELLS, CULTURED; COLLAGEN; EDEMA; FLOW CYTOMETRY; FOOT; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HINDLIMB; HUMANS; MALE; MICE; MICE, INBRED DBA; RECEPTORS, TUMOR NECROSIS FACTOR; SYNOVIAL MEMBRANE; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 0034975580     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(200106)44:6<1444::AID-ART240>3.0.CO;2-Q     Document Type: Article

References (49)

1. Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis
2. Effects of immortalization upon the induction of matrix metalloproteinases in rabbit synovial fibroblasts
3. Tissue inhibitors of metalloproteinases: Evolution, structure and function
4. Analysis Of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: Different profiles in trauma and rheumatoid arthritis
5. Matrix metalloproteinases
6. Increased levels of stromelysin-1 and tissue inhibitor of metalloproteinases-1 in sera from patients with rheumatoid arthritis
7. Synovial cytokine and growth factor regulation of MMPs/TIMPs: Implications for erosions and angiogenesis in early rheumatoid and psoriatic arthritis patients
8. Circulating levels of matrix metalloproteinases MMP-3 and MMP-1, tissue inhibitor of metalloproteinases 1 (TIMP-1), and MMP-1/TIMP-1 complex in rheumatic, disease: Correlation with Clinical activity of rheumatoid arthritis versus other surrogate markers
9. Differential expression of cathepsins B and L compared with matrix metalloproteinases and their respective inhibitors in rheumatoid arthritis and osteoarthritis: A parallel investigation by semiquantitative reverse transcriptase-polymerase chain reaction and immunohistochemistry
10. Imbalance between interstitial collagenase and tissue inhibitor of metalloproteinases 1 in synoviocytes and fibroblasts upon direct contact with stimulated T lymphocytes: Involvement of membrane-associated cytokines
11. Levels of rheumatoid factor isotypes, metalloproteinase-3 and tissue inhibitor of metalloproteinase-1 in synovial fluid from various arthritides
12. Collagen-induced arthritis, an animal model of autoimmunity
13. Systemic administration of TIMP in the treatment of collagen-induced arthritis in mice
14. Gene therapy in osteoarticular diseases: Where are we?
15. Development of recombinant adenoviruses that drive high level expression of the human metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 and -2 genes: Characterization of their infection into rabbit smooth muscle cells and human MCF-7 adenocarcinoma cells
16. Simple methods for preparing recombinant adenoviruses for high efficiency transduction of vascular cells
17. Anticytokine treatment of established type II collagen-induced arthritis in DBA/1 mice: A comparative study using anti-TNFα, anti-IL-1α/β, and IL-1Ra
18. Collagen-induced arthritis in the mouse
19. Adenovirus-mediated transfer of viral IL-10 gene inhibits murine collagen-induced arthritis
20. Inhibition of rheumatoid synovial fibroblast proliferation by antisense oligonucleotides targeting proliferating cell nuclear antigen messenger RNA
21. Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein
22. Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic, cytokine gene to human joints with rheumatoid arthritis
23. Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee
24. Suppression of collagen-induced arthritis through adenovirus-mediated transfer of a modified tumor necrosis factor a receptor gene
25. Amelioration of collagen-induced arthritis by CD95 (Apo-1/Fas)-ligand gene transfer
26. Innate immune mechanisms dominate elimination of adenoviral vectors following in viva administration
27. Systemic viral interleukin-10 gene delivery prevents cartilage invasion by human rheumatoid synovial tissue engrafted in SCID mice
28. Expression of matrix metalloproteinase 9 (96-kd gelatinase B) in human rheumatoid arthritis
29. Serum levels of hyaluronan, anti-genic keratan sulfate, matrix metalloproteinase 3, and tissue inhibitor of metalloproteinases 1 change predictably in rheumatoid arthritis patients who have begun activity after a night of bed rest
30. Serum levels of matrix metalloproteinase-3 in relation to the development of radiological damage in patients with early rheumatoid arthritis
31. Increased expression of extracellular matrix metalloproteinase inducer in rheumatoid synovium
32. Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue
33. Secretory leukocyte protease inhibitor suppresses the inflammation and joint damage of bacterial cell wall-induced arthritis
34. Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure
35. Use of encapsulated cells secreting murine TIMP-2 ameliorates collagen-induced arthritis in mice
36. Paradoxical effects of adenovirus-mediated blockade of TNF activity in murine collagen-induced arthritis
37. Transgenic TIMP-1 inhibits simian virus 40 T antigen-induced hepatocarcinogenesis by impairment of hepatocellular proliferation and tumor angiogenesis
38. Matrix metalloproteinases in angiogenesis: A moving target for therapeutic intervention
39. Divergent effects of tissue inhibitor of metalloproteinase-1 -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro: TIMP-3 promotes apoptosis
40. Binding of active (57 kDa) membrane type 1-matrix metalloproteinase (MT1-MMP) to tissue inhibitor of metalloproteinase (TIMP)-2 regulates MT1-MMP processing and pro-MMP-2 activation
41. Production of tissue inhibitor of metalloproteinases 3 is selectively enhanced by calcium pentosan polysulfate in human rheumatoid synovial fibroblasts
42. Inhibition of the metalloproteinase domain of mouse TACE
43. TIMP-3 induces cell death by stabilizing TNF-alpha receptors on the surface of human colon carcinoma cells
44. Synthetic matrix metalloproteinase inhibitors and tissue inhibitor of metalloproteinase (TIMP)-2, but not TIMP-1, inhibit shedding of tumor necrosis factor-alpha receptors in a human colon adenocarcinoma (Colo 205) cell line
45. Anti-adenovirus immune responses in rats are enhanced by interleukin 4 but not interleukin 10 produced by recombinant adenovirus
46. Tissue-specific consequences of the anti-adenoviral immune response: Implications for cardiac transplants
47. Humoral immune response to the capsid components of recombinant adenoviruses: Routes of immunization modulate virus-induced Ig subclass shifts
48. Long-term humoral and cellular immunity induced by a single immunization with replication-defective adenovirus recombinant vector
49. Tissue inhibitor of metalloproteinases (TIMP-1) stimulates the secretion of collagenase from human skin fibroblasts