Three genes with different functions in transformation are regulated by c-Myb in myeloid cells

Blood Cells, Molecules, and Diseases

Volumn 27, Issue 2, 2001, Pages 483-488

  Wolff, L ^a   Schmidt, M ^a   Koller, R ^a   Haviernik, P ^a   Watson, R ^b   Bies, J ^a,c   Maciag, K ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

c Myb; c myc; INK4b; Oncogene; Transcriptional regulation; Tumor suppressor

Indexed keywords

MESSENGER RNA; PROTEIN BCL 2; PROTEIN C MYB; PROTEIN P15; RNA;

BONE MARROW CELL; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME INHIBITION; GENE ACTIVATION; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE LOCUS; GENETIC CODE; GENETIC TRANSCRIPTION; GENETIC TRANSFORMATION; MURINE LEUKEMIA VIRUS; NONHUMAN; ONCOGENE C MYB; PHENOTYPE; PRIORITY JOURNAL; PROTO ONCOGENE; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

MURINAE; MURINE LEUKEMIA VIRUS;

EID: 0034970862     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.2001.0409     Document Type: Conference Paper

References (11)

1. Myb-induced transformation
2. Only late, nonmitotic stages of granulocyte differentiation in 32Dc13 cells are blocked by ectopic expression of murine c-myb and its truncated forms
3. B-Myb prevents growth arrest associated with terminal differentiation of monocytic cells
4. Regulation of the resident chromosomal copy of c-myc by c-Myb is involved in myeloid leukemogenesis
5. A dominant interfering Myb mutant causes apoptosis in T cells
6. 1 arrest
7. Acceleration of apoptosis in transforming growth factor beta 1-treated M1 cells ectopically expressing B-myb
8. A chronic inflammatory response: Its role in supporting the development of c-myc and c-myb related promonocytic and monocytic tumors in BALB/c mice
9. INK4b CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing
10. Mechanism of c-myc regulation by c-Myb in different cell lineages
11. Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells