Placental villous glucose metabolism and hormone release respond to varying oxygen tensions

Journal of the Society for Gynecologic Investigation

Volumn 4, Issue 5, 1997, Pages 241-246

  Kay, Helen H ^a   Robinette, Brian ^a   Yang Shin, Yeo ^a   Siew, Pearl ^a   Shellhaas, Cynthia S ^a   Tyrey, Lee ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Glucose metabolism; Glycolysis; Oxygen tension; Placental villi

Indexed keywords

CHORIONIC GONADOTROPIN; GLUCOSE; LACTATE DEHYDROGENASE; LACTIC ACID; OXYGEN; PROGESTERONE;

ARTICLE; GLUCOSE INTAKE; GLUCOSE METABOLISM; GLYCOLYSIS; HORMONE RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; OXYGEN TENSION; PLACENTA VILLUS; PRIORITY JOURNAL;

CHORIONIC GONADOTROPIN; CHORIONIC VILLI; ESTRADIOL; FEMALE; GLUCOSE; HORMONES; HUMANS; L-LACTATE DEHYDROGENASE; LACTIC ACID; OXYGEN CONSUMPTION; PERFUSION; PROGESTERONE; TIME FACTORS;

EID: 0030693915     PISSN: 10715576     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1071-5576(97)00060-9     Document Type: Article

References (25)

1. Schneider H, Panigel M, Dancis J. Transfer across the perfused human placenta of antipyrine, sodium, and leucine. Am J Obstet Gynecol. 114:1972;822-828.
2. Wier PJ, Miller RK. In vitro evaluations of human placental functions and toxic responses. Kimmel GL, Kochlar DM. In vitro methods in developmental toxicology Use in defining mechanisms and risk parameters . 1990;1-28 CRC Press, Boca Raton.
3. Kliman HJ, Nestler JE, Sermasi E, Sanger JM, Strauss JF. Purification, characterization and in vitro differentiation of cytotrophoblasts from human term placentae. Endocrinology. 118:1986;1567-1582.
4. Soothill PW, Nicolaides KH, Rodeck CH, Campbell S. Effect of gestational age on fetal and intervillous blood gas and acid-base values in human pregnancy. Fetal Therapy. 1:1986;168-175.
5. 31P magnetic resonance spectroscopy of human placental villi perifused under varying oxygen concentrations. Am J Obstet Gynecol. 168:1993;246-252.
6. Shellhaas CS, Coffman T, Dargie PJ, Killam AP, Kay HH. Intravillous eicosanoid compartmentalization and regulation of placental blood flow. J Soc Gynecol Invest. 4:1997;58-63.
7. User's Guide. Crunch Statistical Package, Version 4. 1991;Crunch Software Corporation, Oakland, CA.
8. Wier PJ, Miller RK, Maulik D, Di Sant'Agnese PA. Toxicity of cadmium in the perfused human placenta. Toxicol Appl Pharmacol. 105:1990;156-171.
9. Illsley NP, Aarnoudse JG, Penfold P, et al. Mechanical and metabolic viability of a placental perfusion system in vitro under oxygenated and anoxic conditions. Placenta. 5:1984;213-226.
10. Cannell GR, Kluch RM, Hamilton SE, Mortimer RH, Hooper WD, Dickinson RG. Markers of physical integrity and metabolic viability of the perfused human placental lobule. Clin Exp Pharmacol Physiol. 15:1988;837-844.
11. Kuhn DC, Crawford MA, Gordon GB, Stuart MJ. Aspects of in vitro placental perfusion Effects of hyperoxia and phenol red . Placenta. 9:1988;201-203.
12. Challier JC, Schneider H, Dancis J. In vitro perfusion of human placenta V. Oxygen consumption . Am J Obstet Gynecol. 126:1976;261-265.
13. Bloxam DL. Human placental energy metabolism Its relevance to in vitro perfusion . Contrib Gynecol Obstet. 13:1985;59-69.
14. Beaconsfield R, Cemerikic B, Genbacev O, Sulovic V. The placenta as a model for toxicity screening of new molecules. Trophoblast Res. 5:1984;381-394.
15. Schneider H, Challier JC, Dancis J. Transfer and metabolism of glucose and lactate in the human placenta studied by a perfusion system in vitro. Placenta. 2:(Suppl):1981;129-138.
16. Burd LI, Jones MD, Simmons MA, Makowski EL, Meschia G, Battaglia FC. Placental production and foetal utilization of lactate and pyruvate. Nature. 254:1975;710-714.
17. Frahm J, Kruger G, Merboldt KD, Kleinschmidt A. Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man. Magn Reson Med. 35:1996;143-148.
18. Hardin CD, Roberts TM. Metabolism of exogenously applied fructose 1,6-biphosphate in hypoxic vascular smooth muscle. Am J Physiol. 267:1994;H2325-H2332.
19. Malek A, Sager R, Altermatt HJ, Gaeng D, Leiser R, Schneider H. Glucose consumption and lactate production of human placental tissue under different conditions of in vitro incubation. J Soc Gynecol Invest. 3:1996;113-120.
20. Challier JC, Hauguel de Mouzon S, Desmaizieres V. Metabolism and transfer of radioactive glucose in the human placenta studied by dual perfusion. Contrib Gynecol Obstet. 13:1985;144-146.
21. Lehninger AL. Biochemistry. 2nd edition. 1975;Worth Publishers, Inc. New York.
22. Huot RI, Foidart JM, Stromberg K. Effects of culture conditions on the synthesis of human chorionic gonadotropin by placental organ cultures. In Vitro. 15:1979;497-502.
23. Stogner SW, Payne DK. Oxygen toxicity. Ann Pharm. 26:1992;1554-1562.
24. Sorem KA, Siler-Khodr TM. Placental prostanoid release in severe intrauterine growth retardation. Placenta. 16:1995;503-515.
25. Siler-Khodr TM, Khodr GS, Valenzuela G, Rhode J. Gonadotropin-releasing hormone effects on placental hormones during gestation I. Alph-human chorionic gonadotropin, human chorionic gonadotropin and human chorionic somatomammotropin . Biol Reprod. 34:1986;245-254.