Insulin resistance associated with leptin deficiency in mice: A possible model for noninsulin-dependent diabetes mellitus

Nutrition Reviews

Volumn 59, Issue 6, 2001, Pages 177-179

  Wolf, G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; LEPTIN; STEROL REGULATORY ELEMENT BINDING PROTEIN;

GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; LIPODYSTROPHY; LIPOGENESIS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS; REVIEW; TRANSGENIC MOUSE;

MUS MUSCULUS;

EID: 0034969302     PISSN: 00296643     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1753-4887.2001.tb07009.x     Document Type: Review

References (6)

1. Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice
2. The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
3. Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: Model for congenital generalized lipodystrophy
4. Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation
5. Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice
6. Effects of enteral carbohydrates on de novo lipogenesis in critically ill patients