Establishment of heterotropic liver tissue mass with direct link to the host liver following implantation of hepatocytes transfected with vascular endothelial growth factor gene in mice

Tissue Engineering

Volumn 7, Issue 3, 2001, Pages 335-344

  Ajioka, Itsuki ^a   Nishio, Reiji ^a   Ikekita, Masahiko ^c   Akaike, Toshihiro ^a   Sasaki, Masato ^b   Enami, Jumpei ^b   Watanabe, Yoshifumi ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b ZENYAKU KOGYO CO LTD   (Japan)

^c TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; SCATTER FACTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL LIVER; CELL SURVIVAL; CELL TRANSPLANTATION; CIRCULATION; CONTROLLED STUDY; GENETIC TRANSFECTION; LIVER CELL; LIVER TRANSPLANTATION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TISSUE GROWTH;

ACTINS; ALBUMINS; ANIMALS; BIOCOMPATIBLE MATERIALS; BIOMEDICAL ENGINEERING; CELL SURVIVAL; COATED MATERIALS, BIOCOMPATIBLE; ENDOTHELIAL GROWTH FACTORS; FEMALE; GENE EXPRESSION; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; HUMANS; LAC OPERON; LIVER; LYMPHOKINES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOVASCULARIZATION, PHYSIOLOGIC; RECOMBINANT PROTEINS; SURFACE PROPERTIES; TRANSFECTION; TRANSPLANTATION, HETEROTOPIC; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0034968823     PISSN: 10763279     EISSN: None     Source Type: Journal    
DOI: 10.1089/10763270152044198     Document Type: Article

References (30)

1. Cell therapy
2. Cell transplantation in the treatment of experimental hepatic failure
3. Studies into the mechanism of reversal of experimental acute hepatic failure by hepatocyte transplantation. 1
4. Effect of viable isolated hepatocytes or hepatocyte fractions on survival rate following galactosamine-induced acute liver failure
5. Replacement of liver function in rats by transplantation of microcarrier-attached hepatocytes
6. Hepatocyte transplantation. A potential treatment for liver disease
7. The effects of transplantation of hepatocytes cultured with insulin on acute liver failure induced by 90% hepatectomy in the rat
8. Significant improvement of survival by intrasplenic hepatocyte transplantation in totally hepatectomized rats
9. Morphology and function of isolated hepatocytes transplanted into rat spleen
10. Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes
11. Regenerative signals for heterotropic hepatocyte transplantation
12. Small intestinal submucosa as a small-caliber venous graft: A novel model for hepatocyte transplantation on synthetic biodegradable polymer scaffolds with direct access to the portal venous system
13. Expression of vascular endothelial growth factor promotes colonization, vascularization, and growth of transplanted hepatic tissues in the mouse
14. Vascular endothelial growth factor. Regulation by cell differentiation and activated second messenger pathways
15. Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators
16. Identification of mouse mammary fibroblast-derived mammary growth factor as hepatocyte growth factor
17. Biochemical studies on liver functions in primary cultured hepatocytes of adult rats. I. Hormonal effects on cell viability and protein synthesis
18. Gene transfection of multicellular spheroid of hepatocytes on an artificial substrate
19. Survival, organization, and function of microcarrier-attached hepatocytes transplanted in rats
20. Role of growth factors and cytokines in hepatic regeneration
21. Regulation and significance of hepatocyte derived matrix metalloproteinases (MMP) in liver remodeling
22. Tumor necrosis factor primes hepatocytes for DNA replication in the rat
23. Hepatocyte transplantation in a model of toxin-induced liver disease: Variable therapeutic effect during replacement of damaged parenchyma by donor cells
24. Angiopoietin-1 protects the adult vasculature against plasma leakage
25. Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1
26. Vascular endothelial growth factor induces endothelial fenestrations in vitro
27. Expression of vascular permeability factor/vascular endothelial growth factor in normal rat tissues
28. A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1)
29. Liver regeneration
30. The extracellular matrix in hepatic regeneration