Superimposition-based protocol as a tool for determining bioactive conformations. I. Application to ligands of the glycinergic receptor (GlyR)

Journal of Molecular Graphics and Modelling

Volumn 19, Issue 3-4, 2001, Pages 331-337

  Gálvez Ruano, Enrique ^a   Iriepa, Isabel ^a   Morreale, Antonio ^a   Boyd, Donald B ^b  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b INDIANA UNIVERSITY   (United States)

Author keywords

Glycinergic receptor; Molecular modelling; Natural templates; Neurotransmitters; Superposition

Indexed keywords

CONFORMATIONS; MOLECULAR DYNAMICS;

PHARMACOPHORE;

MOLECULAR GRAPHICS;

1 AMINOCYCLOHEXANECARBOXYLIC ACID; 2 AMINO 2 METHYLPROPIONIC ACID; 4 AMINOBUTYRIC ACID; 5,6,7,8 TETRAHYDRO 4H ISOXAZOLOL[3,4D]AZEPIN 3 OL; ALANINE; ALCOHOL DERIVATIVE; BICUCULLINE; CARBOXYLIC ACID DERIVATIVE; GLYCINE; GLYCINE RECEPTOR; ISONIPECOTINIC ACID; LIGAND; PITRAZEPIN; PROLINE; SERINE; STRYCHNINE; TAURINE; UNCLASSIFIED DRUG;

AGONIST; ARTICLE; ATOMIC PARTICLE; COMPETITIVE INHIBITION; CONFORMATIONAL TRANSITION; DRUG ANTAGONISM; DRUG STRUCTURE; MOLECULAR DYNAMICS; PHARMACOPHORE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

AMINO ACIDS; BICUCULLINE; BINDING, COMPETITIVE; COMPUTER SIMULATION; DIBENZAZEPINES; GLYCINE; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RECEPTORS, GLYCINE; STRYCHNINE; THERMODYNAMICS;

EID: 0034966142     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1093-3263(00)00081-4     Document Type: Article

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