Randomized placebo-controlled trial of long-term treatment with sibutramine in mild to moderate obesity

Journal of Family Practice

Volumn 50, Issue 6, 2001, Pages 505-512

  Smith, I G ^a  

^a Synexus Ltd   (United Kingdom)

Author keywords

Body weight; Family practice; Obesity; Sibutramine non MESH ; Weight loss

Indexed keywords

ANTIOBESITY AGENT; PLACEBO; SIBUTRAMINE;

ADULT; ARTICLE; BEHAVIOR THERAPY; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET THERAPY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; EXTRASYSTOLE; FEMALE; HEART ARRHYTHMIA; HEART PALPITATION; HUMAN; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; OBESITY; OUTCOMES RESEARCH; RANDOMIZED CONTROLLED TRIAL; SEIZURE; SINGLE BLIND PROCEDURE; WEIGHT REDUCTION; XEROSTOMIA;

ADULT; AGED; APPETITE DEPRESSANTS; BEHAVIOR THERAPY; BODY MASS INDEX; BODY WEIGHT; COMBINED MODALITY THERAPY; CYCLOBUTANES; DOUBLE-BLIND METHOD; FAMILY PRACTICE; FEMALE; HUMANS; MALE; MIDDLE AGED; NUTRITION PHYSIOLOGY; OBESITY; PLACEBOS; PRIMARY HEALTH CARE; SEROTONIN UPTAKE INHIBITORS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; WEIGHT LOSS;

EID: 0034965112     PISSN: 00943509     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Increasing prevalence of overweight among US adults: The National Health and Nutrition Examination Surveys, 1960 to 1991
2. The spread of the obesity epidemic in the United States, 1991-1998
3. Obesity as an independent risk factor for cardiovascular disease: A 26-year follow-up of participants in the Framingham Heart Study
4. Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men
5. Variations in mortality by weight among 750,000 men and women
6. The epidemiology of gallbladder disease: Observations in the Framingham Study
7. Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: The effect of obesity
8. Sleep-apnea and hypoventilation in obesity
9. Health-related quality of life in obese persons seeking treatment
10. Socioeconomic consequences of obesity-the effect of obesity on the individual
11. Body weight and mortality among women
12. Current estimates of the economic cost of obesity in the United States
13. Beneficial health effects of modest weight loss
14. The prevention of obesity
15. Are health care professionals advising obese patients to lose weight?
16. Physician attitudes toward managing obesity: Differences among six specialty groups
17. Treatment of obesity
18. Long-term weight maintenance after an intensive weight-loss program
19. Sibutramine: A novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine
20. Cardiac valvulopathy associated with exposure to fenfluramine or dexfenfluramine: US Department of Health and Human Services Interim Public Health Recommendations, November 1997
21. The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure
22. A case for drug treatment of obesity
23. Dietary treatments for obesity are ineffective
24. Long-term weight loss: The effect of pharmacologic agents
25. Sibutramine: A novel new agent for obesity treatment
26. Thermogenic effects of sibutramine and its metabolites
27. The effect of sibutramine on resting energy expenditure and adrenaline-induced thermogenesis in obese females
28. Long-term maintenance of weight loss after a very-low-calorie diet: A randomized blinded trial of the efficacy and tolerability of sibutramine
29. A double-blind randomized placebo-controlled trial of sibutramine
30. A new approach to the analysis of clinical drug trials with withdrawals
31. The two-sample location problem
32. The one-way layout
33. Long-term pharmacotherapy in the management of obesity
34. The high prevalence of obesity in Michigan primary care practices: An UPRNet study
35. 1999 World Health Organization-International Society of Hypertension guidelines for the management of hypertension
36. Coronary heart disease: Reducing the risk. A worldwide view
37. The Hypertension Optimal Treatment Study and the importance of lowering blood pressure
38. Distribution of adipose tissue and risk of cardiovascular disease and death: A 12-year follow-up of participants in the population study of women in Gothenburg, Sweden
39. Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13-year follow-up of participants in the study of men born in 1913
40. Effect of sibutramine on weight maintenance after weight loss: A randomized trial