Structure of the ask-asd operon and formation of aspartokinase subunits in the cephamycin producer 'Amycolatopsis lactamdurans'

Microbiology

Volumn 147, Issue 6, 2001, Pages 1547-1555

  Hernando Rico V ^a   Martin, J F ^a   Santamarta, I ^a   Liras, P ^a  

^a UNIVERSITY OF LEÓN   (Spain)

Author keywords

Aspartic semialdehyde dehydrogenase; Beta lactams

Indexed keywords

ANTIBODY; ASPARTATE KINASE; ASPARTATE SEMIALDEHYDE DEHYDROGENASE; ASPARTIC ACID; CEPHAMYCIN; GLYCINE; LYSINE; MESSENGER RNA; SERINE; THREONINE; TYROSINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMYCOLATOPSIS LACTAMDURANS; ARTICLE; BACTERIUM MUTANT; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CISTRON; CONTROLLED STUDY; CORYNEBACTERIUM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SUBUNIT; ESCHERICHIA COLI; GENE MUTATION; GENE STRUCTURE; GENETIC COMPLEMENTATION; GENETIC TRANSCRIPTION; GENETIC TRANSFORMATION; GRAM POSITIVE BACTERIUM; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OPERON; PRIORITY JOURNAL; RIBOSOME;

AMYCOLATOPSIS LACTAMDURANS; BACTERIA (MICROORGANISMS); CORYNEBACTERIA; CORYNEBACTERIUM; ESCHERICHIA COLI; POSIBACTERIA;

EID: 0034964912     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-147-6-1547     Document Type: Article

References (47)

1. Characterization of the ribosomal rrnD operon of the cephamycin producer 'Nocardia lactamdurans' shows that this actinomycete belongs to the genus Amycolatopsis
2. A rapid alkaline extraction procedure for screening recombinant plasmid DNA
3. Organization and nucleotide sequence of the Bacillus subtilis diaminopimelate operon, a cluster of genes encoding the first three enzymes of diaminopimelate synthesis and dipicolinate synthase
4. One-step preparation of competent Escherichia coli: Transformation and storage of bacterial cells in the same solution
5. Isolation and characterization of the asparto-kinase and aspartate semialdehyde dehydrogenase operon from mycobacteria
6. Regulation of the biosynthesis amino acids of the aspartate family in coliform bacteria and Pseudomonas
7. A gene encoding lysine 6-aminotransferase, which forms the β-lactam precursor α-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans
8. Analysis of the codon usage of the cephamycin C producer A. lactamdurans
9. Regulation of enzymes of lysine biosynthesis in Corynebacterium glutamicum
10. Molecular aspects of lysine, threonine, and isoleucine biosynthesis in Corynebacterium glutamicum
11. Gene structure and expression of the Corynebacterium flavum N13 ask-asd operon
12. Δ-I-Piperideine-6-carboxylate dehydrogenase, a new enzyme that forms α-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes
13. Cloning and characterization of the asd gene of Salmonella typhimurium: Use in stable maintenance of recombinant plasmids in Salmonella vaccine strains
14. Sporulation and the production of serine proteases and cephamycin C by Streptomyces lactamdurans
15. The codon preference plot: Graphic analysis of protein coding sequences and prediction of gene expression
16. Nucleotide sequence of the asd gene of Escherichia coli: Absence of a typical attenuation signal
17. CLUSTAL V: Improved software for multiple sequencing alignment
18. Molecular genetic analysis of the region containing the essential Pseudomonas aeruginosa asd gene encoding aspartate-β-semialdehyde dehydrogenase
19. A rapid boiling method for the preparation of bacterial plasmids
20. Expression of Streptococcus mutans aspartate-semialdehyde dehydrogenase gene cloned into plasmid pBR322
21. Aspartokinase genes lysCα and lysCβ overlap and are adjacent to the aspartate β-semialdehyde dehydrogenase gene asd in Corynebacterium glutamicum
22. Genetic and biochemical analysis of the aspartokinase from Corynebacterium glutamicum
23. Isolation of deoxyribonucleic acid and ribosomal ribonucleic acid from bacteria
24. Efficient transformation of the cephamycin C producer Nocardia lactamdurans and development of shuttle and promoter-probe cloning vectors
25. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
26. Streptomyces akiyoshiensis differs from other Gram-positive bacteria in the organization of a core biosynthetic pathway gene for aspartate family amino acids
27. Cloning and location of a gene governing lysine ε-aminotransferase, an enzyme initiating β-lactam biosynthesis in Streptomyces spp
28. Precursor flux control through targeted chromosomal insertion of the lysine epsilon-aminotransferase (lat) gene in cephamycin C biosynthesis
29. Effects of enhanced lysine epsilon-aminotransferase activity on cephamycin biosynthesis in Streptomyces clavuligerus
30. Clonación y caracterización molecular de los genes biosintéticos de treonina (thrC) y lisina de Brevibacterium lactofermentum
31. Molecular control mechanisms of lysine and threonine biosynthesis in amino acid-producing corynebacteria: Redirecting carbon flow
32. New aspects of genes and enzymes for β-lactam antibiotic biosynthesis
33. α-Aminoadipyl-cysteinyl-valine synthetases in β-lactam producing organisms. From Abraham's discoveries to novel concepts of non-ribosomal peptide synthesis
34. Secondary metabolites
35. Regulation of cephamycin C synthesis, aspartokinase, dihydrodipicolinic acid synthetase, and homoserine dehydrogenase by aspartic acid family amino acids in Streptomyces clavuligerus
36. The pcd gene encoding piperideine-6-carboxylate dehydrogenase involved in biosynthesis of α-amino-adipic acid is located in the cephamycin cluster of Streptomyces clavuligerus
37. Induction of L-lysine ε-aminotransferase by L-lysine in Streptomyces clavuligerus, producer of cephalosporins
38. DNA sequencing with chain-terminating inhibitors
39. Concerted inhibition and its reversal by end products of aspartate kinase in Brevibacterium flavum
40. Feedback inhibition and repression of aspartokinase activity in E. coli and Saccharomyces cerevisiae
41. Mapping of the structural genes of three aspartokinases and of the two homoserine dehydrogenases of Escherichia coli K12
42. Comparison of the three aspartokinase isozymes in Bacillus subtilis Marburg and 168
43. Sequence analysis and expression of the aspartokinase and aspartate semialdehyde dehydrogenase operon from rifamycin SV-producing Amycolatopsis mediterranei
44. Expression in Escherichia coli, purification and kinetic analysis of the aspartokinase and aspartate semialdehyde dehydrogenase from the rifamycin SV-producing Amycolatopsis mediterranei U32