CD46 (membrane cofactor protein) associates with multiple β1 integrins and tetraspans

European Journal of Immunology

Volumn 30, Issue 3, 2000, Pages 900-907

  Lozahic, Stéphanie ^a   Christiansen, Dale ^b   Manié, Serge ^b   Gerlier, Denis ^b   Billard, Martine ^a   Boucheix, Claude ^a   Rubinstein, Eric ^a  

^a HÔPITAL PAUL BROUSSE   (France)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

CD46; Integrin; Measles virus; Tetraspan

Indexed keywords

BETA1 INTEGRIN; CD9 ANTIGEN; MEMBRANE COFACTOR PROTEIN; MONOCLONAL ANTIBODY;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MEASLES VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; VIRUS ADSORPTION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, CD29; ANTIGENS, CD46; ANTIGENS, SURFACE; CELL LINE; CHO CELLS; CRICETINAE; CROSS-LINKING REAGENTS; HELA CELLS; HUMANS; INTEGRIN ALPHA6BETA4; INTEGRINS; MEASLES VIRUS; MEMBRANE FUSION; MEMBRANE GLYCOPROTEINS; MICE; PROTEIN BINDING;

EID: 0033994664     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200003)30:3<900::AID-IMMU900>3.0.CO;2-X     Document Type: Article

References (38)

1. Maecker, H. T., Todd, S. C. and Levy, S., The tetraspanin superfamily: molecular facilitators. FASEB J. 1997. 11: 428-442.
2. Hemler, M. E., Mannion, B. A. and Berditchevski, F., Association of TM4SF proteins with integrins: relevance to cancer. Biochim. Biophys. Acta 1996. 1287: 67-71.
3. Ikeyama, S., Koyama, M., Yamaoko, M., Sasada, R. and Miyake, M., Suppression of cell motility and metastasis by transfection with human motility-related protein (MRP-1/CD9) DNA. J. Exp. Med. 1993. 177: 1231-1237.
4. Radford, K. J., Thorne, R. F. and Hersey, P., Regulation of tumor cell motility and migration by CD63 in a human melanoma cell line. J. Immunol. 1997. 158: 3353-3358.
5. Dong, J. T., Suzuki, H., Pin, S. S., Bova, S., Schalken, J. A., Isaacs, W. B., Barrett, J. C. and Isaacs, J. T., Down-regulation of the KAII metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation of allelic loss. Cancer Res. 1996. 56: 4387-4390.
6. Miyake, M., Koyama, M., Seno, M. and Ikeyama, C., Identification of the mobility-related protein (MRP-1), recognized by monoclonal antibody M31-15, which inhibits cell motility. J. Exp. Med. 1991. 174: 1347-1354.
7. Rubinstein, E., Le Naour, F., Billard, M., Prenant, M. and Boucheix, C., CD9 antigen is an accessory subunit of the VLA integrin complexes. Eur. J. Immunol. 1994. 24: 3005-3013.
8. Lagaudrière-Gesbert, C., Le Naour, F., Lebel-Binay, S., Billard, M., Lemichez, E., Boucheix, C., Conjeaud, H. and Rubinstein, E., Functional analysis of four tetraspans, CD9, CD53, CD81, and CD82, suggests a common role in costimulation, cell adhesion, and migration: only CD9 upregulates HB-EGF activity. Cell, Immunol. 1997. 182: 105-112.
9. Yabez-Mo, M., Alfranca, A., Cabanas, C., Mazaruela, M., Tejedor, R., Ursa, M. A., Ashman, L. K., de Landazuri, M. O. and Sanchez-Madrid, F., Regulation of endothelial cell motility by complexes of tetraspan molecules CD81/TAPA-1 and CD151/PETA-3 with α3β1 integrin localized at endothelial lateral junctions. J. Cell Biol. 1998. 4: 791-804.
10. Sincock, P. M., Fitter, S., Parton, R. G., Berndt, M. C., Gamble, J. R. and Ashman, L. K., PETA-3/CD151, a member of the transmembrane 4 superfamily, is localised to the plasma membrane and endocytic system of endothelial cells, associates with multiple integrins and modulates cell function. J. Cell Sci. 1999. 112: 33-844.
11. Rubinstein, E., Le Naour, F., Lagaudrière, C., Billard, M., Conjeaud, H. and Boucheix, C., CD9, CD63, CD81 and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins. Eur. J. Immunol. 1996. 26: 2657-2665.
12. Berditchevski, F., Zutter, M. M. and Hemler, M. E., Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins). Mol. Biol. Cell 1996. 7: 193-207.
13. Radford, K. J., Thorne, R. F. and Hersey, P., CD63 associates with transmembrane 4 superfamily members, CD9 and CD81, and with β1 integrins in human melanoma. Biochem. Biophys. Res. Commun. 1996. 222: 13-18.
14. Angelisova, P., Hilgert, I. and Horejsi, V., Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/ C33) with MHC class II glycoproteins. Immunogenetics 1994. 39: 249-256.
15. Imai, T. and Yoshie, O., C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells. J. Immunol. 1993. 151: 6470-6481.
16. Horváth, G., Serru, V., Clay, D., Billard, M., Boucheix, C. and Rubinstein, E., CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82. J. Biol. Chem. 1998. 273: 30537-30543.
17. Yauch, R. L., Berditchevski, F., Harler, M. B., Reichner, J. and Hemler, M. E., Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration. Mol. Biol. Cell 1998. 9: 2751-2765.
18. Serru, V., Le Naour, F., Billard, M., Azorsa, D. O., Lanza, F., Boucheix, C. and Rubinstein, E., Selective Tetraspan/integrin complexes (CD81/α4β1, CD151/α3β1, CD151/α6β1) under conditions disrupting tetraspan interactions. Biochem. J. 1999. 340: 103-111.
19. Liszewski, M. K., Post, T. W. and Atkinson, J. P., Membrane cofactor protein (MCP or CD46): Newest member of the regulators of complement activation gene cluster. Annu. Rev. Immunol. 1991. 9: 431-455.
20. Dörig, R. E., Marcil, A., Chopra, A. and Richardson, C. D., The human CD46 molecule is a receptor for measles virus (Edmonston strain). Cell 1993. 75: 295-305.
21. Naniche, D., Varior-Krishnan, G., Cervoni, F., Wild, T. R, Rossi, B., Rabourdin-Combe, C. and Gerlier, D., Human membrane cofactor protein (CD46) acts as a cellular receptor for measles virus. J. Virol. 1993. 67: 6025-6032.
22. Shaw, S., Antibodies and molecules of the 5th International Workshop of Leukocyte Differentiation antigens. In Schlossman, S., Boumsell, L, Gilks, W., Harlan, J., Tedder, T. and Todd, R. (Eds.) Leukocyte typing V: white cell differentiation antigens. Oxford University Press, Oxford 1994.
23. Gerlier, D., Varior-Krishnan, V. and Devaux, P., CD46-mediated measles virus entry: a first key to host-range specificity. Trends Microbiol. 1995. 3: 338-345.
24. Imai, T., Fukudome, K., Takagi, S., Nagira, M., Furuse, M., Nishimura, M. and Yoshie, O., CD33 antigen recognized by monoclonal antibodies inhibitory to human T cell leukemia virus type 1-induced syncytium formation is a member of a new family of transmembrane proteins including CD9, CD37, CD53 and CD63. J. Immunol. 1992. 149: 2879-2886.
25. Willett, B. J., Flynn, J. N. and Hosie, M. J., FIV infection of the domestic cat: an animal model for AIDS, Immunol. Today 1997. 18: 182-189.
26. Löffler, S., Lottspeich, F., Lanza, F., Azorsa, D. O., ter Meulen, V. and Schneider-Schaulies, J., CD9, a tetraspan transmembrane protein renders cells susceptible to canine distemper virus. J. Virol. 1997. 71: 42-49.
27. Karp, C. L., Wysocka, M., Wahl, L. M., Ahearn, J. M., Cuomo, P. J., Sherry, B., Trinchieri, G. and Griffin, D. E., Mechanism of suppression of cell-mediated immunity by measles virus. Science 1996. 273: 288-231.
28. Hirano, A., Yang, Z., Katayama, Y., Korte-Sarfaty, J. and Wong, T. C., Human CD46 enhances nitric oxide production in mouse macrophages in response to measles virus infection in the presence of gamma interferon: dependence on the CD46 cytoplasmic domains. J. Virol. 1999. 73: 4776-4785.
29. Wong, T. C., Yant, S., Harder, B. J., Korte-Sarfaty, J. and Hirano, A., The cytoplasmic domains of complement regulatory protein CD46 interact with multiple kinases in macrophages. J. Leukoc. Biol. 1997. 62: 892-900.
30. Karp, C. L., Measles: immunosuppression, interleukin-12 and complement receptors, Immunol. Rev. 1999. 168: 91-101.
31. Azorsa, D. O., Moog, S., Cazenave, J. P. and Lanza, F, A general approach to the generation of monoclonal antibodies against members of the tetraspanin superfamily using recombinant GST fusion proteins. J. Immunol. Methods 1999. 229: 35-48.
32. Lebel-Binay, S., Lagaudrière, C., Fradelizi, D. and Conjeaud, H., CD82, member of the tetra-span-transmembrane protein family, as a costimulatory protein for T cell activation. J. Immunol. 1995. 155: 101-110.
33. Bartolazzi, A., Fraioli, P., Tarone, G. and Natali, P. G., Generation and characterization of the murine monoclonal antibody M-KID 2 to VLA-3 integrin. Hybridoma 1991. 10: 707-720.
34. Seya, T., Iwata, K., Hara, T., Matsumoto, M. and Nagasawa, S., CD46 Workshop: a panel of monoclonal antibodies against CD46 that block complement regulatory activity and measles virus receptor fusion of CD46. In Kishimoto, T., Kikutani, H., von dem Borne, A. E. G. K., Goyert, S. M., Mason, D. Y., Miyasaka, M., Moretta, L., Okumura, K., Shaw, S., Springer, T., Sugamura, K. and Zola, H. (Eds.) Leukocyte Typing VI, Garland Publishing, Inc, New York 1997, pp 507-509.
35. Giraudon, P. and Wild, T. F., Correlation between epitopes on hemagglutinin of measles virus and biological activities: passive protection by monoclonal antibodies is related to their hemagglutination inhibiting activity. Virology 1985. 144: 46-58.
36. Christiansen, D., Loveland, B., Kyriakou, P., Lanteri, M., Escoffier, C. and Gerlier, D., Interaction of CD46 with Measles Virus (MV): Accessory Role of CD46 SCR IV J. Gen. Virol. (in press).
37. Alkhatib, G., Broder, C. C. and Berger, E. A., Cell type-specific fusion cofactors determine human immunodeficiency virus type I tropism for T-cell lines versus primary macrophages. J. Virol. 1996. 70: 5487-5494.
38. Nussbaum, O., Broder, C. C. and Berger, E. A., Fusogenic mechanisma of enveloped-virus glycoproteins anlyzed by a novel recombinant vaccinia virus-based assay quantitating cell fusiondependent reporter gene activity. J. Virol. 1994. 68: 5411-5422.