Oral polymeric N-acetyl-D-glucosamine and osteoarthritis

Journal of the American Osteopathic Association

Volumn 101, Issue 6, 2001, Pages 339-344

  Rubin, B R ^a   Talent, J M ^a   Kongtawelert, P ^a   Pertusi, R M ^a   Forman, M D ^a   Gracy, R W ^a  

^a University of North Texas Health Science Center   (United States)

Author keywords

Glucosamine; Osteoarthritis

Indexed keywords

CHONDROITIN SULFATE; IBUPROFEN; MANGANESE DERIVATIVE; N ACETYLGLUCOSAMINE; POLYMER;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; RANDOMIZED CONTROLLED TRIAL; SYMPTOMATOLOGY;

ACETYLGLUCOSAMINE; ADMINISTRATION, ORAL; ADULT; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; GLUCOSAMINE; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS; PAIN MEASUREMENT; PILOT PROJECTS; RANGE OF MOTION, ARTICULAR; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME;

EID: 0034958074     PISSN: 00986151     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Epidemiology of hip and knee osteoarthritis
2. The dangerous divide: Alternative attitudes survey - What arthritis doctors and patients really think
3. Enhanced synovial production of hyaluronic acid may explain rapid clinical response for high dose glucosamine in osteoarthritis
4. Relevance of animal models to clinical disease. Glucosamine sulfate reduces the structural changes in dog experimental osteoarthritis: Beneficial effect through suppression of the expression of collagenase-1
5. The redox state in lymphocytes from patients with rheumatoid arthritis
6. Reactive oxygen species: The unavoidable environmental insult?
7. Antioxidant activity of synovial fluid, hyaluronic acid, and two sub-components of hyaluronic acid
8. Glucosamine sulfate for osteoarthritis
9. Glucosamine, chondroitin and manganese ascorbate for degenerative joint disease of the knee or low back: A randomized, double-blind placebo-controlled pilot study
10. Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis
11. Glucosamine
12. Absorption, distribution and excretion of radioactivity after a single intravenous or oral administration of [14C] glucosamine to the rat
13. Pharmacokinetics of glucosamine in the dog and in man
14. Pharmakokinetics of glucosamine in man
15. Pilot study of oral polymeric N-acetylglucosamine as a potential treatment for patients with osteoarthritis
16. Oral polymeric N-acetyl-D-glucosamine and osteoarthritis
17. Modulation of native chondroitin sulfate structure in tissue development and disease
18. Chitosan and its use as a pharmaceutical excipient
19. Chitosan: A unique polysaccharide for drug delivery
20. Human enzymatic activities related to the therapeutic administration of chitin derivatives