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Volumn 29, Issue 2, 2001, Pages 135-139
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Predicting drug pharmacokinetics in humans from in vitro metabolism studies
a
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Author keywords
Cytochrome P450; Drug metabolism
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Indexed keywords
CYTOCHROME P450;
CYTOCHROME P450 1A2;
CYTOCHROME P450 2C19;
CYTOCHROME P450 2C9;
CYTOCHROME P450 2D6;
CYTOCHROME P450 3A4;
DEXTROMETHORPHAN;
DIAZEPAM;
DILTIAZEM;
ERYTHROMYCIN;
FURAFYLLINE;
IBUPROFEN;
KETOCONAZOLE;
METOPROLOL;
NAPROXEN;
OMEPRAZOLE;
PROPRANOLOL;
QUINIDINE;
RECOMBINANT ENZYME;
REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;
SULFAPHENAZOLE;
TESTOSTERONE;
TOLBUTAMIDE;
VERAPAMIL;
CONFERENCE PAPER;
CORRELATION FUNCTION;
DRUG CLEARANCE;
DRUG METABOLISM;
DRUG OXIDATION;
DRUG SAFETY;
ENZYME INHIBITION;
ENZYME KINETICS;
ESCHERICHIA COLI;
HUMAN;
IC 50;
IN VITRO STUDY;
LIPOPHILICITY;
LIVER MICROSOME;
PREDICTION;
PRIORITY JOURNAL;
PROTEIN EXPRESSION;
ESCHERICHIA COLI;
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EID: 0034956777
PISSN: 03005127
EISSN: None
Source Type: Journal
DOI: 10.1042/bst0290135 Document Type: Conference Paper |
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Times cited : (54)
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References (11)
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